Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement

1.3K Views

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05:25 min

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July 21st, 2023

DOI :

10.3791/65613-v

July 21st, 2023

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Yuanqi Liu*¹^,²^,³^,⁴^,⁵, Siyuan Sun*¹^,²^,³^,⁴^,⁵, Ziyi Jiang*⁶, Xinyi Gong¹^,²^,³^,⁴^,⁵, Yiling Yang¹^,²^,³^,⁴^,⁵, Yanfei Zhu¹^,²^,³^,⁴^,⁵, Hongyuan Xu¹^,²^,³^,⁴^,⁵, Anting Jin¹^,²^,³^,⁴^,⁵, Xiangru Huang¹^,²^,³^,⁴^,⁵, Xin Gao¹^,²^,³^,⁴^,⁵, Tingwei Lu¹^,²^,³^,⁴^,⁵, Jingyi Liu¹^,²^,³^,⁴^,⁵, Xinyu Wang¹^,²^,³^,⁴^,⁵, Qinggang Dai²^,³^,⁴^,⁵^,⁷, Lingyong Jiang¹^,²^,³^,⁴^,⁵

¹Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, ²College of Stomatology, Shanghai Jiao Tong University, ³National Center for Stomatology, ⁴National Clinical Research Center for Oral Diseases, ⁵Shanghai Key Laboratory of Stomatology, ⁶Shanghai Starriver Bilingual School, ⁷The 2nd Dental Center, Ninth People’s Hospital, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine

Summary

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Inducible Knockout Mice

Alveolar Bone Remodeling

Orthodontic Tooth Movement

Micro computed Tomography

Histological Analysis

Mechanobiology

Chapters in this video

0:00

Introduction

1:58

Murine Orthodontic Tooth Movement (OTM) Model

3:43

Murine Alveolar Bone Specimen Collection

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