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The Generation of Closed Femoral Fractures in Mice: A Model to Study Bone Healing

DOI :

10.3791/58122-v

August 16th, 2018

August 16th, 2018

14,540 Views

1Department of Anatomy and Cell Biology, Indiana University School of Medicine

The murine closed femoral fracture model is a powerful platform to study fracture healing and novel therapeutic strategies to accelerate bone regeneration. The goal of this surgical protocol is to generate unilateral closed femoral fractures in mice using an intramedullary steel rod to stabilize the femur.

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