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East China University of Science and Technology

2 ARTICLES PUBLISHED IN JoVE

Chemistry

A Closed-Type Wireless Nanopore Electrode for Analyzing Single Nanoparticles

Rui Gao^*1, Ling-Fei Cui^*1, Lin-Qi Ruan¹, Yi-Lun Ying¹, Yi-Tao Long¹

¹Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering, East China University of Science and Technology

Here, we present a protocol for fabrication of a closed-type wireless nanopore electrode and subsequent electrochemical measurement of single nanoparticle collisions.

Bioengineering

In Vivo Osteo-organoid Approach for Harvesting Therapeutic Hematopoietic Stem/Progenitor Cells

Wenchao Zhang^1,2, Xue Wei^1,2, Qingliang Wang^1,2, Kai Dai^1,2,3, Jing Wang^1,2,4, Changsheng Liu^2,3,4

¹State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, ²Engineering Research Center for Biomedical Materials of the Ministry of Education, East China University of Science and Technology, ³Key Laboratory for Ultrafine Materials of the Ministry of Education, East China University of Science and Technology, ⁴Frontiers Science Center for Materiobiology and Dynamic Chemistry, East China University of Science and Technology

Here, we established in vivo osteo-organoids triggered by bone morphogenetic protein-2-loaded gelatin scaffolds to harvest therapeutic hematopoietic stem/progenitor cells for the reconstruction of a damaged hematopoietic and immune system. Overall, this approach can provide a promising cell source for cell therapies.