Results: Fibular Nerve Injury is a Reliable Assay for Identifying Neuromuscular Junction Repair Factors
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Conclusion
Transcripción
The overall goal of this peripheral nerve injury method is to reliably examine regenerating neuromuscular junctions in mice. This method will help us identify the molecular, cellular, and functional changes associated with regenerating neuromuscul
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We have developed a nerve injury method to reliably examine muscle reinnervation, and thus regeneration of neuromuscular junctions in mice. This technique involves injuring the common fibular nerve via a simple and highly reproducible surgery. Muscle reinnervation in then assessed by whole-mounting the extensor digitorum longus muscle.