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Department of Medicine,
Solna and CMM,
Respiratory Medicine Unit,
Department of Medicine, Solna and CMM, Respiratory Medicine Unit
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Decreased serum and bronchoalveolar lavage levels of Clara cell secretory protein (CC16) is associated with bronchiolitis obliterans syndrome and airway neutrophilia in lung transplant recipients.
Transplantation Apr, 2002 | Pubmed ID: 11981419
Glucocorticoids regulate the CCSP and CYP2B1 promoters via C/EBPbeta and delta in lung cells.
Biochemical and biophysical research communications May, 2002 | Pubmed ID: 12051744
Synergistic transactivation of the differentiation-dependent lung gene Clara cell secretory protein (secretoglobin 1a1) by the basic region leucine zipper factor CCAAT/enhancer-binding protein alpha and the homeodomain factor Nkx2.1/thyroid transcription factor-1.
The Journal of biological chemistry Oct, 2002 | Pubmed ID: 12161423
Characterization of human thioredoxin-like 2. A novel microtubule-binding thioredoxin expressed predominantly in the cilia of lung airway epithelium and spermatid manchette and axoneme.
The Journal of biological chemistry Apr, 2003 | Pubmed ID: 12569107
C/EBP transcription factors in the lung epithelium.
American journal of physiology. Lung cellular and molecular physiology Oct, 2003 | Pubmed ID: 12959923
Regulation of postnatal lung development and homeostasis by estrogen receptor beta.
Molecular and cellular biology Dec, 2003 | Pubmed ID: 14612399
Differential regulation of estrogen receptor (ER)alpha and ERbeta in primate mammary gland.
The Journal of clinical endocrinology and metabolism Jan, 2005 | Pubmed ID: 15507513
Decreased CCAAT/enhancer binding protein transcription factor activity in chronic bronchitis and COPD.
Chest Apr, 2005 | Pubmed ID: 15821213
Decreased serum levels of clara cell secretory protein (CC16) are associated with bronchiolitis obliterans and may permit early diagnosis in patients after allogeneic stem-cell transplantation.
Transplantation May, 2005 | Pubmed ID: 15912112
Glucocorticoids increase C/EBPbeta activity in the lung epithelium via phosphorylation.
Biochemical and biophysical research communications Aug, 2005 | Pubmed ID: 16009338
Ectopic expression of C/EBPalpha in the lung epithelium disrupts late lung development.
American journal of physiology. Lung cellular and molecular physiology Oct, 2006 | Pubmed ID: 16698852
Gene expression analysis after prenatal tracheal ligation in fetal rat as a model of stimulated lung growth.
Journal of pediatric surgery Apr, 2009 | Pubmed ID: 19361631
Gene expression analysis in hypoplastic lungs in the nitrofen model of congenital diaphragmatic hernia.
Journal of pediatric surgery Jul, 2010 | Pubmed ID: 20638522
Connective tissue growth factor expression pattern in lung development.
Experimental lung research Oct, 2010 | Pubmed ID: 20939759
Increased pulmonary Wnt (wingless/integrated)-signaling in patients with sarcoidosis.
Respiratory medicine Feb, 2011 | Pubmed ID: 21146388
Chronic respiratory aeroallergen exposure in mice induces epithelial-mesenchymal transition in the large airways.
PloS one , 2011 | Pubmed ID: 21283768
Lung epithelial CCAAT/enhancer-binding protein-β is necessary for the integrity of inflammatory responses to cigarette smoke.
American journal of respiratory and critical care medicine Jul, 2011 | Pubmed ID: 21562127
The emerging role of C/EBPs in glucocorticoid signaling: lessons from the lung.
The Journal of endocrinology Mar, 2012 | Pubmed ID: 22045755
Airway epithelial cell differentiation during lung organogenesis requires C/EBPα and C/EBPβ.
Developmental dynamics : an official publication of the American Association of Anatomists May, 2012 | Pubmed ID: 22411169
Lung epithelial-C/EBPβ contributes to LPS-induced inflammation and its suppression by formoterol.
Biochemical and biophysical research communications Jun, 2012 | Pubmed ID: 22634316
A Relationship between Epithelial Maturation, Bronchopulmonary Dysplasia, and Chronic Obstructive Pulmonary Disease.
Pulmonary medicine , 2012 | Pubmed ID: 23320163
Activity of neutrophil elastase reflects the progression of acute pancreatitis.
Scandinavian journal of clinical and laboratory investigation Sep, 2013 | Pubmed ID: 23819644
Elevated exhaled nitric oxide in allergen-provoked asthma is associated with airway epithelial iNOS.
PloS one , 2014 | Pubmed ID: 24587191
Karolinska Institutet
AstraZeneca Global Medicines Development
Abraham B. Roos1,
Tove Berg1,
Kerstin M. Ahlgren1,
Johan Grunewald1,
Magnus Nord1,2
1Department of Medicine, Solna and CMM, Respiratory Medicine Unit, Karolinska Institutet,
2Safety Science, Global Regulator Affairs & Patient Safety, AstraZeneca Global Medicines Development
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