Tarjei S. Mikkelsen

What makes us human?

Improving genome annotations using phylogenetic profile anomaly detection.

A human-specific gene in microglia.

DNA sequence and analysis of human chromosome 18.

The case for selection at CCR5-Delta32.

Genome sequence, comparative analysis and haplotype structure of the domestic dog.

DNA sequence and analysis of human chromosome 8.

A bivalent chromatin structure marks key developmental genes in embryonic stem cells.

System-wide genomic and biochemical comparisons of sialic acid biology among primates and rodents: Evidence for two modes of rapid evolution.

A second fatty acid amide hydrolase with variable distribution among placental mammals.

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites.

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences.

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.

Dissecting direct reprogramming through integrative genomic analysis.

Genome-scale DNA methylation maps of pluripotent and differentiated cells.

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.

Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution.

Comparative epigenomic analysis of murine and human adipogenesis.

The NIH Roadmap Epigenomics Mapping Consortium.

Mapping and analysis of chromatin state dynamics in nine human cell types.

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay.

A unique regulatory phase of DNA methylation in the early mammalian embryo.

Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO.

Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica.

Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells.

Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay.

Cellular source and mechanisms of high transcriptome complexity in the mammalian testis.

microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN.

Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes.

High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis.

Genome-scale CRISPR-Cas9 knockout screening in human cells.

Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells.

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells.

ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells.

Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling.

The regulatory landscape of osteogenic differentiation.

Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes.

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5' Sites.