Anne Grapin-Botton

Development and diseases of the pancreas.

Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate.

Ductal cells of the pancreas.

Antero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesis.

Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development.

Pancreas development and cancer: Wnt/beta-catenin at issue...

FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo.

Evolution of the mechanisms and molecular control of endoderm formation.

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.

The genetic programme of pancreatic beta-cells: basic science for the development of beta-cell therapy. Workshop on programming pancreatic beta-cells.

Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis.

Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development.

Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia.

RNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factors.

COUP-TFII controls mouse pancreatic β-cell mass through GLP-1-β-catenin signaling pathways.

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.

Diabetes imaging-quantitative assessment of islets of Langerhans distribution in murine pancreas using extended-focus optical coherence microscopy.

Patterning and shaping the endoderm in vivo and in culture.

Dual lineage-specific expression of Sox17 during mouse embryogenesis.

生成转录的启动子部分替换 sentinels 不同信号传导通路在胚胎干细胞和老鼠。

Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.

Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment.

The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation.

Artificial three-dimensional niches deconstruct pancreas development in vitro.

The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube.