Alessandro Lugli

High-throughput tissue microarray analysis of G1-cyclin alterations in classical Hodgkin's lymphoma indicates overexpression of cyclin E1.

Calretinin expression in human normal and neoplastic tissues: a tissue microarray analysis on 5233 tissue samples.

Expression of B-cell markers in classical hodgkin lymphoma: a tissue microarray analysis of 330 cases.

Macrofollicular variant of papillary carcinoma of the thyroid: a histologic, cytologic, and immunohistochemical study of 3 cases and review of the literature.

Frequent EpCam protein expression in human carcinomas.

Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer.

Hepatocyte paraffin 1 expression in human normal and neoplastic tissues: tissue microarray analysis on 3,940 tissue samples.

Prevalence of KIT expression in human tumors.

Proposal of a morphologic bone marrow response score for imatinib mesylate treatment in chronic myelogenous leukemia.

Patterns of gene amplification in gastrointestinal stromal tumors (GIST).

EphB2 expression across 138 human tumor types in a tissue microarray: high levels of expression in gastrointestinal cancers.

Construction and validation of a bone marrow tissue microarray.

Scoring of p53, VEGF, Bcl-2 and APAF-1 immunohistochemistry and interobserver reliability in colorectal cancer.

Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancer.

Role of the mitogen-activated protein kinase and phosphoinositide 3-kinase/AKT pathways downstream molecules, phosphorylated extracellular signal-regulated kinase, and phosphorylated AKT in colorectal cancer-a tissue microarray-based approach.

Prognostic value of cell cycle and apoptosis regulatory proteins in mismatch repair-proficient colorectal cancer: a tissue microarray-based approach.

Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancer.

Napoleon Bonaparte's gastric cancer: a clinicopathologic approach to staging, pathogenesis, and etiology.

Differential significance of tumour infiltrating lymphocytes in sporadic mismatch repair deficient versus proficient colorectal cancers: a potential role for dysregulation of the transforming growth factor-beta pathway.

Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancer.

Loss of APAF-1 expression is associated with tumour progression and adverse prognosis in colorectal cancer.

Close association between HER-2 amplification and overexpression in human tumors of non-breast origin.

Loss of raf-1 kinase inhibitor protein expression is associated with tumor progression and metastasis in colorectal cancer.

Value of staining intensity in the interpretation of immunohistochemistry for tumor markers in colorectal cancer.

Multimarker phenotype predicts adverse survival in patients with lymph node-negative colorectal cancer.

Node-negative colorectal cancer at high risk of distant metastasis identified by combined analysis of lymph node status, vascular invasion, and Raf-1 kinase inhibitor protein expression.

Chromosomal instability in gastric mucosa-associated lymphoid tissue lymphomas: a fluorescent in situ hybridization study using a tissue microarray approach.

Local recurrence in mismatch repair-proficient colon cancer predicted by an infiltrative tumor border and lack of CD8+ tumor-infiltrating lymphocytes.

RHAMM, p21 combined phenotype identifies microsatellite instability-high colorectal cancers with a highly adverse prognosis.

Differential diagnostic and functional role of the multi-marker phenotype CDX2/CK20/CK7 in colorectal cancer stratified by mismatch repair status.

Is immunohistochemical epidermal growth factor receptor expression overestimated as a prognostic factor in head-neck squamous cell carcinoma? A retrospective analysis based on a tissue microarray of 365 carcinomas.

Tumor border configuration added to TNM staging better stratifies stage II colorectal cancer patients into prognostic subgroups.

Combined histomorphologic and immunohistochemical phenotype to predict the presence of vascular invasion in colon cancer.

Is the improved prognosis of p16 positive oropharyngeal squamous cell carcinoma dependent of the treatment modality?

Urokinase-type plasminogen activator is a marker of aggressive phenotype and an independent prognostic factor in mismatch repair-proficient colorectal cancer.

High frequency of tumor-infiltrating FOXP3(+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients.

Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis.

Systematic assessment of the prognostic impact of membranous CD44v6 protein expression in colorectal cancer.

Invasive front of colorectal cancer: dynamic interface of pro-/anti-tumor factors.

ABCG5-positivity in tumor buds is an indicator of poor prognosis in node-negative colorectal cancer patients.

Combined analysis of specific KRAS mutation, BRAF and microsatellite instability identifies prognostic subgroups of sporadic and hereditary colorectal cancer.

Role of the VEGF ligand to receptor ratio in the progression of mismatch repair-proficient colorectal cancer.

Archaeology dig into the duodenal biopsy.

The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients.

Role of tumor size in the pre-operative management of rectal cancer patients.

Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases.

Tumor infiltration by FcγRIII (CD16)+ myeloid cells is associated with improved survival in patients with colorectal carcinoma.

Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer.

Co-overexpression of p21 and Ki-67 in head and neck squamous cell carcinoma relative to a significantly poor prognosis.

Tumor budding predicts response to anti-EGFR therapies in metastatic colorectal cancer patients.

TIA-1 cytotoxic granule-associated RNA binding protein improves the prognostic performance of CD8 in mismatch repair-proficient colorectal cancer.

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: tumor budding as oncotarget.

The medical mystery of Napoleon Bonaparte: an interdisciplinary exposé.

Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features.

Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.

Intratumoral budding as a potential parameter of tumor progression in mismatch repair-proficient and mismatch repair-deficient colorectal cancer patients.

VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients.

Characterization of the immunological microenvironment of tumour buds and its impact on prognosis in mismatch repair-proficient and -deficient colorectal cancers.

Standardization of whole slide image morphologic assessment with definition of a new application: Digital slide dynamic morphometry.

Intra-tumoral budding in preoperative biopsy specimens predicts lymph node and distant metastasis in patients with colorectal cancer.

Stratification and Prognostic Relevance of Jass's Molecular Classification of Colorectal Cancer.

Metastases and primary tumors around dental implants: A literature review and case report of peri-implant pulmonary metastasis.

Diagnostic reproducibility of tumour budding in colorectal cancer: a multicentre, multinational study using virtual microscopy.

The impact of CpG island methylator phenotype and microsatellite instability on tumour budding in colorectal cancer.

Role of intra- and peritumoral budding in the interdisciplinary management of rectal cancer patients.

Characterization of CDKN2A(p16) methylation and impact in colorectal cancer: systematic analysis using pyrosequencing.

Proposal for a 10-high-power-fields scoring method for the assessment of tumor budding in colorectal cancer.

Cancer classification using the Immunoscore: a worldwide task force.

Tumor budding score based on 10 high-power fields is a promising basis for a standardized prognostic scoring system in stage II colorectal cancer.

The additional facet of immunoscore: immunoprofiling as a possible predictive tool for cancer treatment.

Clinical impact of programmed cell death ligand 1 expression in colorectal cancer.

Next-generation tissue microarray (ngTMA) increases the quality of biomarker studies: an example using CD3, CD8, and CD45RO in the tumor microenvironment of six different solid tumor types.

High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor.

The apoptotic and proliferation rate of tumour budding cells in colorectal cancer outlines a heterogeneous population of cells with various impacts on clinical outcome.

Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.

Loss of Cdx2 Expression in Primary Tumors and Lymph Node Metastases is Specific for Mismatch Repair-Deficiency in Colorectal Cancer.

Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency.

Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC).

HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker.

The tumor border configuration of colorectal cancer as a histomorphological prognostic indicator.

CD8/CD45RO T-cell infiltration in endoscopic biopsies of colorectal cancer predicts nodal metastasis and survival.

Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics.

Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients.

Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial.

Tumor budding in upper gastrointestinal carcinomas.