Christopher D. Kane

Proteomic analysis of calcium/calmodulin-dependent protein kinase I and IV in vitro substrates reveals distinct catalytic preferences.

Differential regulation of the cynomolgus, human, and rat acyl-CoA oxidase promoters by PPARalpha.

Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies.

The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding.

Molecular characterization of novel and selective peroxisome proliferator-activated receptor alpha agonists with robust hypolipidemic activity in vivo.

Synthesis and evaluation of novel alpha-heteroaryl-phenylpropanoic acid derivatives as PPARalpha/gamma dual agonists.

Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis.

Recent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discovery.

Recent Advances in Botulinum Neurotoxin Inhibitor Development.