Department of Horticulture and Landscape Architecture
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Identification of a novel, orally bioavailable histamine H(3) receptor antagonist based on the 4-benzyl-(1H-imidazol-4-yl) template.
Bioorganic & medicinal chemistry letters Mar, 2002 | Pubmed ID: 11958998
The bifunctional LKR/SDH locus of plants also encodes a highly active monofunctional lysine-ketoglutarate reductase using a polyadenylation signal located within an intron.
Plant physiology Sep, 2002 | Pubmed ID: 12226495
Impact of preimmunization on adenoviral vector expression and toxicity in a subcutaneous mouse cancer model.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2002 | Pubmed ID: 12231170
The activity of the Arabidopsis bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase enzyme of lysine catabolism is regulated by functional interaction between its two enzyme domains.
The Journal of biological chemistry Dec, 2002 | Pubmed ID: 12393892
Renal principal cell-specific expression of green fluorescent protein in transgenic mice.
American journal of physiology. Renal physiology Dec, 2002 | Pubmed ID: 12426236
Increased lysine synthesis coupled with a knockout of its catabolism synergistically boosts lysine content and also transregulates the metabolism of other amino acids in Arabidopsis seeds.
The Plant cell Apr, 2003 | Pubmed ID: 12671081
Effects on telomerase activity and associated-protein of hRPE cells by TGF-beta 1.
Yan ke xue bao = Eye science / "Yan ke xue bao" bian ji bu Mar, 2003 | Pubmed ID: 12852090
Lysine metabolism is concurrently regulated by synthesis and catabolism in both reproductive and vegetative tissues.
Plant physiology May, 2004 | Pubmed ID: 15122025
Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2005 | Pubmed ID: 15951419
Open-chest 31P magnetic resonance spectroscopy of mouse heart at 4.7 Tesla.
Journal of magnetic resonance imaging : JMRI Dec, 2006 | Pubmed ID: 17096395
Application of tetrahydrofuran dispersant in microemulsion for fabricating titania mesoporous thin film.
Journal of colloid and interface science Oct, 2007 | Pubmed ID: 17632120
Discovery of a highly potent series of oxazole-based phosphodiesterase 4 inhibitors.
Bioorganic & medicinal chemistry letters Sep, 2007 | Pubmed ID: 17683932
Novel nitrite sensing using a palladium-polyphenosafranine nano-composite.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry Aug, 2007 | Pubmed ID: 17690432
Multiple condylomata lata: a case report.
International journal of dermatology Jan, 2008 | Pubmed ID: 18173604
Virus-induced gene silencing as a tool to identify host genes affecting viral pathogenicity.
Methods in molecular biology (Clifton, N.J.) , 2008 | Pubmed ID: 18370286
Benzimidazole-substituted (3-phenoxypropyl)amines as histamine H3 receptor ligands.
Bioorganic & medicinal chemistry letters Sep, 2008 | Pubmed ID: 18752952
Isolation, structural determination, synthesis and quantitative determination of impurities in Intron-A, leached from a silicone tubing.
Journal of pharmaceutical and biomedical analysis Feb, 2009 | Pubmed ID: 19150187
Structural determinants for histamine H(1) affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs.
Bioorganic & medicinal chemistry letters Sep, 2009 | Pubmed ID: 19660947
Deciphering transcriptional and metabolic networks associated with lysine metabolism during Arabidopsis seed development.
Plant physiology Dec, 2009 | Pubmed ID: 19783646
Induced ER chaperones regulate a receptor-like kinase to mediate antiviral innate immune response in plants.
Cell host & microbe Nov, 2009 | Pubmed ID: 19917500
Function of endoplasmic reticulum calcium ATPase in innate immunity-mediated programmed cell death.
The EMBO journal Mar, 2010 | Pubmed ID: 20075858
Virus-induced gene silencing offers a functional genomics platform for studying plant cell wall formation.
Molecular plant Sep, 2010 | Pubmed ID: 20522525
SGT1 positively regulates the process of plant cell death during both compatible and incompatible plant-pathogen interactions.
Molecular plant pathology Sep, 2010 | Pubmed ID: 20695999
ATP production rate via creatine kinase or ATP synthase in vivo: a novel superfast magnetization saturation transfer method.
Circulation research Mar, 2011 | Pubmed ID: 21293002
Cyclic hydroxyamidines as amide isosteres: discovery of oxadiazolines and oxadiazines as potent and highly efficacious γ-secretase modulators in vivo.
Journal of medicinal chemistry Jan, 2012 | Pubmed ID: 22098494
A three-step protocol for lead optimization: quick identification of key conformational features and functional groups in the SAR studies of non-ATP competitive MK2 (MAPKAPK2) inhibitors.
Bioorganic & medicinal chemistry letters Jan, 2012 | Pubmed ID: 22169260
SAR studies of C2 ethers of 2H-pyrano[2,3-d]pyrimidine-2,4,7(1H,3H)-triones as nicotinic acid receptor (NAR) agonist.
Bioorganic & medicinal chemistry letters Jan, 2012 | Pubmed ID: 22209457
Co-effect of insulin resistance and biomarkers of inflammation and endothelial dysfunction on hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension May, 2012 | Pubmed ID: 22278626
Nebulizing conditions of pneumatic electrospray ionization significantly influence electrolyte effects on compound measurement.
Journal of mass spectrometry : JMS Mar, 2012 | Pubmed ID: 22431465
A histone acetyltransferase regulates active DNA demethylation in Arabidopsis.
Science (New York, N.Y.) Jun, 2012 | Pubmed ID: 22700931
The formation of percolative composites with a high dielectric constant and high conductivity.
Angewandte Chemie (International ed. in English) Sep, 2012 | Pubmed ID: 22887953
Myocardin-like protein 2 regulates TGFβ signaling in embryonic stem cells and the developing vasculature.
Development (Cambridge, England) Oct, 2012 | Pubmed ID: 22899851
Myocardin regulates BMP10 expression and is required for heart development.
The Journal of clinical investigation Oct, 2012 | Pubmed ID: 22996691
Aequorin-based luminescence imaging reveals stimulus- and tissue-specific Ca2+ dynamics in Arabidopsis plants.
Molecular plant Mar, 2013 | Pubmed ID: 23371933
[Histological study of dual factor inducing axial vascularization in double-layered scaffold].
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology Apr, 2013 | Pubmed ID: 23662568
Double repression in jasmonate-mediated plant defense.
Molecular cell May, 2013 | Pubmed ID: 23706816
Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties.
Bioorganic & medicinal chemistry letters Mar, 2014 | Pubmed ID: 24556380
An Rrp6-like protein positively regulates noncoding RNA levels and DNA methylation in Arabidopsis.
Molecular cell May, 2014 | Pubmed ID: 24726328
A novel molecularly imprinted material based on magnetic halloysite nanotubes for rapid enrichment of 2,4-dichlorophenoxyacetic acid in water.
Journal of hazardous materials Jul, 2014 | Pubmed ID: 24862469
The ABA receptor PYL8 promotes lateral root growth by enhancing MYB77-dependent transcription of auxin-responsive genes.
Science signaling Jun, 2014 | Pubmed ID: 24894996
The Discovery of Pyridone and Pyridazone Heterocycles as γ-Secretase Modulators.
ACS medicinal chemistry letters Jul, 2010 | Pubmed ID: 24900193
Discovery of a potent nicotinic Acid receptor agonist for the treatment of dyslipidemia.
ACS medicinal chemistry letters Feb, 2011 | Pubmed ID: 24900295
Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia.
ACS medicinal chemistry letters Jan, 2012 | Pubmed ID: 24900372
Synthesis and SAR Studies of Fused Oxadiazines as γ-Secretase Modulators for Treatment of Alzheimer's Disease.
ACS medicinal chemistry letters Nov, 2012 | Pubmed ID: 24900409
Discovery of a novel series of potent MK2 non-ATP competitive inhibitors using 1,2-substituted azoles as cis-amide isosteres.
Bioorganic & medicinal chemistry letters Aug, 2014 | Pubmed ID: 24913714
Regulation of Active DNA Demethylation by an α-Crystallin Domain Protein in Arabidopsis.
Molecular cell Aug, 2014 | Pubmed ID: 25002145
Xiaohong Zhu1,
Aaron Taylor2,
Shenyu Zhang1,
Dayong Zhang1,3,
Ying Feng1,4,
Gaimei Liang1,5,
Jian-Kang Zhu1,6
1Department of Horticulture and Landscape Architecture, Purdue University,
2Bindley Bioscience Center, Purdue University,
3Institute of Biotechnology, Jiangsu Academy of Agricultural Sciences,
4College of Environmental & Resource Science, Zhejiang University,
5Dryland Agriculture Research Centre, Shanxi Academy of Agricultural Sciences,
6Shanghai Center for Plant Stress Biology, Chinese Academy of Sciences