MRC/ARUK Centre for Musculoskeletal Ageing Research
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Activation of Ras and the mitogen-activated protein kinase pathway promotes protein degradation in muscle cells of Caenorhabditis elegans.
Molecular and cellular biology Jun, 2002 | Pubmed ID: 12024031
Activated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans.
The EMBO journal Oct, 2003 | Pubmed ID: 14517244
Chemically defined medium and Caenorhabditis elegans.
BMC biotechnology Oct, 2003 | Pubmed ID: 14580264
Surviving atmospheric spacecraft breakup.
Wilderness & environmental medicine , 2005 | Pubmed ID: 15813144
Signal-transduction networks and the regulation of muscle protein degradation.
The international journal of biochemistry & cell biology Oct, 2005 | Pubmed ID: 16125109
Caenorhabditis elegans survives atmospheric breakup of STS-107, space shuttle Columbia.
Astrobiology Dec, 2005 | Pubmed ID: 16379525
Decreased expression of myogenic transcription factors and myosin heavy chains in Caenorhabditis elegans muscles developed during spaceflight.
The Journal of experimental biology Aug, 2006 | Pubmed ID: 16888068
Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction.
The Journal of experimental biology Oct, 2006 | Pubmed ID: 17023606
Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans.
The EMBO journal Feb, 2007 | Pubmed ID: 17290229
unc-94 encodes a tropomodulin in Caenorhabditis elegans.
Journal of molecular biology Dec, 2007 | Pubmed ID: 17976644
Genomic response of the nematode Caenorhabditis elegans to spaceflight.
Advances in space research : the official journal of the Committee on Space Research (COSPAR) , 2008 | Pubmed ID: 18392117
Biochemical and Molecular Biological Analyses of space-flown nematodes in Japan, the First International Caenorhabditis elegans Experiment (ICE-First).
Microgravity science and technology Sep, 2007 | Pubmed ID: 19513185
The glutaredoxin GLRX-21 functions to prevent selenium-induced oxidative stress in Caenorhabditis elegans.
Toxicological sciences : an official journal of the Society of Toxicology Dec, 2010 | Pubmed ID: 20833709
The effectiveness of RNAi in Caenorhabditis elegans is maintained during spaceflight.
PloS one , 2011 | Pubmed ID: 21673804
Identification and functional clustering of genes regulating muscle protein degradation from amongst the known C. elegans muscle mutants.
PloS one , 2011 | Pubmed ID: 21980350
Remote automated multi-generational growth and observation of an animal in low Earth orbit.
Journal of the Royal Society, Interface / the Royal Society Mar, 2012 | Pubmed ID: 22130552
Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans.
PLoS genetics Jan, 2012 | Pubmed ID: 22253611
The next phase of life-sciences spaceflight research: Harnessing the power of functional genomics.
Communicative & integrative biology Nov, 2011 | Pubmed ID: 22446523
Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans.
Neurotoxicology Apr, 2012 | Pubmed ID: 22560997
Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans.
Scientific reports , 2012 | Pubmed ID: 22768380
Using Multiple Phenotype Assays and Epistasis Testing to Enhance the Reliability of RNAi Screening and Identify Regulators of Muscle Protein Degradation.
Genes , 2012 | Pubmed ID: 23152949
Integrated control of protein degradation in C. elegans muscle.
Worm Jul, 2012 | Pubmed ID: 23457662
Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases.
Antioxidants & redox signaling Jan, 2014 | Pubmed ID: 23641861
Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway.
American journal of physiology. Endocrinology and metabolism Jul, 2013 | Pubmed ID: 23695213
Evaluation of the Fluids Mixing Enclosure System for Life Science Experiments During a Commercial Caenorhabditis elegans Spaceflight Experiment.
Advances in space research : the official journal of the Committee on Space Research (COSPAR) Jun, 2013 | Pubmed ID: 23794777
Knockdown of the C. elegans kinome identifies kinases required for normal protein homeostasis, mitochondrial network structure, and sarcomere structure in muscle.
Cell communication and signaling : CCS , 2013 | Pubmed ID: 24060339
Spaceflight and ageing: reflecting on Caenorhabditis elegans in space.
Gerontology , 2014 | Pubmed ID: 24217152
A validation of the application of D(2)O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans.
American journal of physiology. Endocrinology and metabolism Mar, 2014 | Pubmed ID: 24381002
The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans.
Neurotoxicology Mar, 2014 | Pubmed ID: 24406377