Lakshmi Santhanam

Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols.

Structural diversity of peroxidase-catalyzed oxidation products of o-methoxyphenols.

Rac1 leads to phosphorylation-dependent increase in stability of the p66shc adaptor protein: role in Rac1-induced oxidative stress.

Sos-mediated activation of rac1 by p66shc.

Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism.

Single exposure gamma-irradiation amplifies xanthine oxidase activity and induces endothelial dysfunction in rat aorta.

Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction.

Endothelial arginase II: a novel target for the treatment of atherosclerosis.

Selective fluorescent labeling of S-nitrosothiols (S-FLOS): a novel method for studying S-nitrosation.

Arginase and vascular aging.

Cyclohexanone contamination from extracorporeal circuits impairs cardiovascular function.

Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.

Dietary inhibition of xanthine oxidase attenuates radiation-induced endothelial dysfunction in rat aorta.

Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness.

Oral atorvastatin therapy restores cutaneous microvascular function by decreasing arginase activity in hypercholesterolaemic humans.

S-nitrosation of arginase 1 requires direct interaction with inducible nitric oxide synthase.

Upregulation of inducible nitric oxide synthase contributes to attenuated cutaneous vasodilation in essential hypertensive humans.

Nitric oxide regulates tissue transglutaminase localization and function in the vasculature.

Nitric oxide regulates non-classical secretion of tissue transglutaminase.

Upregulation of arginase-II contributes to decreased age-related myocardial contractile reserve.

Hydrogen sulfide decreases reactive oxygen in a model of lung transplantation.

Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin.

Inhaled hydrogen sulfide improves graft function in an experimental model of lung transplantation.

A physiologic and biochemical profile of clinically rejected lungs on a normothermic ex vivo lung perfusion platform.

Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans.

Nitroprusside inhibits calcium-induced impairment of red blood cell deformability.

Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice.

Arterial stiffening precedes systolic hypertension in diet-induced obesity.

Contribution of arginase activation to vascular dysfunction in cigarette smoking.

Exercise, vascular stiffness, and tissue transglutaminase.

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.

Melanopsin mediates light-dependent relaxation in blood vessels.