Caroline A. Owen

The club cell and its protein, CC16: time to shine.

ADAM-33 surfaces as an asthma gene.

Inducible expression of tissue inhibitor of metalloproteinases-resistant matrix metalloproteinase-9 on the cell surface of neutrophils.

Neutrophil elastase in human atherosclerotic plaques: production by macrophages.

Membrane-bound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinase.

Proteinases and oxidants as targets in the treatment of chronic obstructive pulmonary disease.

Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells.

The sulfate groups of chondroitin sulfate- and heparan sulfate-containing proteoglycans in neutrophil plasma membranes are novel binding sites for human leukocyte elastase and cathepsin G.

CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice.

Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization.

Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease.

ADAM8: a new therapeutic target for asthma.

Matrix metalloproteinase-8 inactivates macrophage inflammatory protein-1 alpha to reduce acute lung inflammation and injury in mice.

Matrix metalloproteinases: all the RAGE in the acute respiratory distress syndrome.

Polymorphonuclear neutrophils move into the fast lane in chronic obstructive pulmonary disease.

Genetically Manipulated Mouse Models of Lung Disease: Potential and Pitfalls.

Interleukin-18: the master regulator driving destructive and remodeling processes in the lungs of patients with chronic obstructive pulmonary disease?

Inflammation in COPD: implications for management.

Selenoprotein N deficiency in mice is associated with abnormal lung development.

The role of systemic inflammatory biomarkers to predict mortality in chronic obstructive pulmonary disease.

Profibrotic activities for matrix metalloproteinase-8 during bleomycin-mediated lung injury.

Adipose-derived stem cells weigh in as novel therapeutics for acute lung injury.

Adam8 limits the development of allergic airway inflammation in mice.

Rapid lung function decline in smokers is a risk factor for COPD and is attenuated by angiotensin-converting enzyme inhibitor use.

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.

Comparison of arterial and venous blood biomarker levels in chronic obstructive pulmonary disease.

Functional characterization of polymorphisms in the peptidase inhibitor 3 (elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome.

Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis.

Idiopathic pulmonary fibrosis and coronary artery disease.

Effects of sex hormones on bronchial reactivity during the menstrual cycle.

ADAM9 is a novel product of polymorphonuclear neutrophils: regulation of expression and contributions to extracellular matrix protein degradation during acute lung injury.

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD.

Folliculin regulates cell-cell adhesion, AMPK, and mTORC1 in a cell-type-specific manner in lung-derived cells.

A Novel Nonhuman Primate Model of Cigarette Smoke-Induced Airway Disease.