Carol Box

The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma of the head and neck.

Cell migration/invasion assays and their application in cancer drug discovery.

Syk tyrosine kinase is linked to cell motility and progression in squamous cell carcinomas of the head and neck.

Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck.

Tumour-microenvironmental interactions: paths to progression and targets for treatment.

MAPK and PI3K signalling differentially regulate angiogenic and lymphangiogenic cytokine secretion in squamous cell carcinoma of the head and neck.

Angiogenic functions of voltage-gated Na+ Channels in human endothelial cells: modulation of vascular endothelial growth factor (VEGF) signaling.

Flexible targeting of ErbB dimers that drive tumorigenesis by using genetically engineered T cells.

Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling.

Molecular markers of response and resistance to EGFR inhibitors in head and neck cancers.

Two-dimensional vs. three-dimensional in vitro tumor migration and invasion assays.

Tumor spheroid-based migration assays for evaluation of therapeutic agents.

A novel serum protein signature associated with resistance to epidermal growth factor receptor tyrosine kinase inhibitors in head and neck squamous cell carcinoma.