Department of Biology
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Genomic analysis of uncultured marine viral communities.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2002 | Pubmed ID: 12384570
Marine phage genomics.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology Dec, 2002 | Pubmed ID: 12470812
Novel antibiotics: macrocyclic peptides designed to trap Holliday junctions.
Organic letters Jan, 2003 | Pubmed ID: 12529117
Mechanism of inhibition of site-specific recombination by the Holliday junction-trapping peptide WKHYNY: insights into phage lambda integrase-mediated strand exchange.
Journal of molecular biology Mar, 2003 | Pubmed ID: 12628247
Mutations at residues 282, 286, and 293 of phage lambda integrase exert pathway-specific effects on synapsis and catalysis in recombination.
Journal of bacteriology Apr, 2003 | Pubmed ID: 12670991
Genome sequences of two closely related Vibrio parahaemolyticus phages, VP16T and VP16C.
Journal of bacteriology Nov, 2003 | Pubmed ID: 14563879
Reversible inhibitors of lambda integrase-mediated recombination efficiently trap Holliday junction intermediates and form the basis of a novel assay for junction resolution.
The Journal of biological chemistry Jan, 2004 | Pubmed ID: 14625310
Unequal access of chromosomal regions to each other in Salmonella: probing chromosome structure with phage lambda integrase-mediated long-range rearrangements.
Molecular microbiology Apr, 2004 | Pubmed ID: 15066024
New views of the bacterial chromosome.
EMBO reports Sep, 2004 | Pubmed ID: 15319779
Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.
The Journal of biological chemistry Mar, 2005 | Pubmed ID: 15591069
Holliday junction-binding peptides inhibit distinct junction-processing enzymes.
Proceedings of the National Academy of Sciences of the United States of America May, 2005 | Pubmed ID: 15867153
Complete genome sequence of phiHSIC, a pseudotemperate marine phage of Listonella pelagia.
Applied and environmental microbiology Jun, 2005 | Pubmed ID: 15933034
New wrinkles and folds in site-specific recombination.
Molecular cell Aug, 2005 | Pubmed ID: 16109368
DNA repair, a novel antibacterial target: Holliday junction-trapping peptides induce DNA damage and chromosome segregation defects.
Molecular microbiology Feb, 2006 | Pubmed ID: 16430689
New peptide inhibitors of type IB topoisomerases: similarities and differences vis-a-vis inhibitors of tyrosine recombinases.
Journal of molecular biology Nov, 2006 | Pubmed ID: 16996084
Spermidine biases the resolution of Holliday junctions by phage lambda integrase.
Nucleic acids research , 2007 | Pubmed ID: 17182631
Probing nucleoid structure in bacteria using phage lambda integrase-mediated chromosome rearrangements.
Methods in enzymology , 2007 | Pubmed ID: 17352925
The temperate marine phage PhiHAP-1 of Halomonas aquamarina possesses a linear plasmid-like prophage genome.
Journal of virology Jul, 2008 | Pubmed ID: 18448537
Interactions between branched DNAs and peptide inhibitors of DNA repair.
Nucleic acids research Sep, 2008 | Pubmed ID: 18689438
Peptide wrwycr inhibits the excision of several prophages and traps holliday junctions inside bacteria.
Journal of bacteriology Apr, 2009 | Pubmed ID: 19181810
Staphylococcus aureus SarA is a regulatory protein responsive to redox and pH that can support bacteriophage lambda integrase-mediated excision/recombination.
Molecular microbiology Dec, 2009 | Pubmed ID: 19919677
Lysogeny and sporulation in Bacillus isolates from the Gulf of Mexico.
Applied and environmental microbiology Feb, 2010 | Pubmed ID: 20008174
Control of directionality in the DNA strand-exchange reaction catalysed by the tyrosine recombinase TnpI.
Nucleic acids research Apr, 2010 | Pubmed ID: 20044348
An antimicrobial peptide that targets DNA repair intermediates in vitro inhibits Salmonella growth within murine macrophages.
Antimicrobial agents and chemotherapy May, 2010 | Pubmed ID: 20176906
Small molecule functional analogs of peptides that inhibit lambda site-specific recombination and bind Holliday junctions.
Bioorganic & medicinal chemistry letters Aug, 2010 | Pubmed ID: 20598532
Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes.
Molecular diversity Nov, 2011 | Pubmed ID: 21938393
Escherichia coli enterobactin synthesis and uptake mutants are hypersensitive to an antimicrobial peptide that limits the availability of iron in addition to blocking Holliday junction resolution.
Microbiology (Reading, England) Feb, 2012 | Pubmed ID: 22096151
Artificial neural networks trained to detect viral and phage structural proteins.
PLoS computational biology , 2012 | Pubmed ID: 22927809
Similarities between exogenously- and endogenously-induced envelope stress: the effects of a new antibacterial molecule, TPI1609-10.
PloS one , 2012 | Pubmed ID: 23071502
wrwyrggrywrw is a single-chain functional analog of the Holliday junction-binding homodimer, (wrwycr)2.
Peptides Feb, 2013 | Pubmed ID: 23291222
Structure and function of a cyanophage-encoded peptide deformylase.
The ISME journal Jun, 2013 | Pubmed ID: 23407310
Tumor cell death mediated by peptides that recognize branched intermediates of DNA replication and repair.
PloS one , 2013 | Pubmed ID: 24244353
Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers.
PLoS pathogens Apr, 2014 | Pubmed ID: 24722773
Replication fork integrity and intra-S phase checkpoint suppress gene amplification.
Nucleic acids research Mar, 2015 | Pubmed ID: 25672394
Savannah E. Sanchez1,
Daniel A. Cuevas2,
Jason E. Rostron1,
Tiffany Y. Liang3,
Cullen G. Pivaroff1,
Matthew R. Haynes1,
Jim Nulton4,
Ben Felts4,
Barbara A. Bailey4,
Peter Salamon4,
Robert A. Edwards1,5,6,
Alex B. Burgin7,
Anca M. Segall1,
Forest Rohwer1
1Department of Biology, San Diego State University,
2Computational Science Research Center, San Diego State University,
3Bioinformatics and Medical Informatics Research Center, San Diego State University,
4Department of Mathematics and Statistics, San Diego State University,
5Department of Computer Science, San Diego State University,
6Mathematics and Computer Science Division, Argonne National Laboratory,
7SPARC Committee, Broad Institute