Anca M. Segall

Genomic analysis of uncultured marine viral communities.

Marine phage genomics.

Novel antibiotics: macrocyclic peptides designed to trap Holliday junctions.

Mechanism of inhibition of site-specific recombination by the Holliday junction-trapping peptide WKHYNY: insights into phage lambda integrase-mediated strand exchange.

Mutations at residues 282, 286, and 293 of phage lambda integrase exert pathway-specific effects on synapsis and catalysis in recombination.

Genome sequences of two closely related Vibrio parahaemolyticus phages, VP16T and VP16C.

Reversible inhibitors of lambda integrase-mediated recombination efficiently trap Holliday junction intermediates and form the basis of a novel assay for junction resolution.

Unequal access of chromosomal regions to each other in Salmonella: probing chromosome structure with phage lambda integrase-mediated long-range rearrangements.

New views of the bacterial chromosome.

Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.

Holliday junction-binding peptides inhibit distinct junction-processing enzymes.

Complete genome sequence of phiHSIC, a pseudotemperate marine phage of Listonella pelagia.

New wrinkles and folds in site-specific recombination.

DNA repair, a novel antibacterial target: Holliday junction-trapping peptides induce DNA damage and chromosome segregation defects.

New peptide inhibitors of type IB topoisomerases: similarities and differences vis-a-vis inhibitors of tyrosine recombinases.

Spermidine biases the resolution of Holliday junctions by phage lambda integrase.

Probing nucleoid structure in bacteria using phage lambda integrase-mediated chromosome rearrangements.

The temperate marine phage PhiHAP-1 of Halomonas aquamarina possesses a linear plasmid-like prophage genome.

Interactions between branched DNAs and peptide inhibitors of DNA repair.

Peptide wrwycr inhibits the excision of several prophages and traps holliday junctions inside bacteria.

Staphylococcus aureus SarA is a regulatory protein responsive to redox and pH that can support bacteriophage lambda integrase-mediated excision/recombination.

Lysogeny and sporulation in Bacillus isolates from the Gulf of Mexico.

Control of directionality in the DNA strand-exchange reaction catalysed by the tyrosine recombinase TnpI.

An antimicrobial peptide that targets DNA repair intermediates in vitro inhibits Salmonella growth within murine macrophages.

Small molecule functional analogs of peptides that inhibit lambda site-specific recombination and bind Holliday junctions.

Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes.

Escherichia coli enterobactin synthesis and uptake mutants are hypersensitive to an antimicrobial peptide that limits the availability of iron in addition to blocking Holliday junction resolution.

Artificial neural networks trained to detect viral and phage structural proteins.

Similarities between exogenously- and endogenously-induced envelope stress: the effects of a new antibacterial molecule, TPI1609-10.

wrwyrggrywrw is a single-chain functional analog of the Holliday junction-binding homodimer, (wrwycr)2.

Structure and function of a cyanophage-encoded peptide deformylase.

Tumor cell death mediated by peptides that recognize branched intermediates of DNA replication and repair.

Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers.

Replication fork integrity and intra-S phase checkpoint suppress gene amplification.