Laboratory of Neurodegenerative Diseases,
Department of Anatomy,
LKS Faculty of Medicine,
Laboratory of Neurodegenerative Diseases, Department of Anatomy, LKS Faculty of Medicine
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Enhanced survival and regeneration of axotomized retinal ganglion cells by a mixture of herbal extracts.
Journal of neurotrauma Mar, 2002 | Pubmed ID: 11939504
Postnatal development of nicotinamide adenine dinucleotide phosphate-diaphorase-positive neurons in the retina of the golden hamster.
The Journal of comparative neurology May, 2002 | Pubmed ID: 11954033
Expression of trkA, trkB, and trkC in injured and regenerating retinal ganglion cells of adult rats.
Investigative ophthalmology & visual science Jun, 2002 | Pubmed ID: 12037005
Development of the regenerative capacity of postnatal axotomized rat spinal motoneurons.
Neuroreport Jun, 2002 | Pubmed ID: 12060811
Total retinal nitric oxide production is increased in intraocular pressure-elevated rats.
Experimental eye research Oct, 2002 | Pubmed ID: 12387787
Retinal nerve fiber layer measurement of the Hong Kong chinese population by optical coherence tomography.
Journal of glaucoma Dec, 2002 | Pubmed ID: 12483090
Axonal regeneration of retinal ganglion cells after optic nerve pre-lesions and attachment of normal or pre-degenerated peripheral nerve grafts.
Visual neuroscience Sep-Oct, 2002 | Pubmed ID: 12507332
Retinal nerve fiber layer measurement by optical coherence tomography in glaucoma suspects with short-wavelength perimetry abnormalities.
Journal of glaucoma Feb, 2003 | Pubmed ID: 12567111
Intraocular elevation of cyclic AMP potentiates ciliary neurotrophic factor-induced regeneration of adult rat retinal ganglion cell axons.
Molecular and cellular neurosciences Jan, 2003 | Pubmed ID: 12595238
Axotomy induces cytochrome c release in retinal ganglion cells.
Neuroreport Feb, 2003 | Pubmed ID: 12598746
A morphometric study of optic axons regenerated in a sciatic nerve graft of adult rats.
Restorative neurology and neuroscience , 2000 | Pubmed ID: 12671213
Inhibition of caspases promotes long-term survival and reinnervation by axotomized spinal motoneurons of denervated muscle in newborn rats.
Experimental neurology Jun, 2003 | Pubmed ID: 12781992
Retinal nerve fiber loss pattern in high-tension glaucoma by optical coherence tomography.
Journal of glaucoma Jun, 2003 | Pubmed ID: 12782845
Axonal regeneration of Clarke's neurons beyond the spinal cord injury scar after treatment with chondroitinase ABC.
Experimental neurology Jul, 2003 | Pubmed ID: 12821386
Inflammatory response associated with axonal injury to spinal motoneurons in newborn rats.
Developmental neuroscience Jan-Feb, 2003 | Pubmed ID: 12876433
Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity.
The Journal of biological chemistry Dec, 2003 | Pubmed ID: 12975376
c-Jun expression in surviving and regenerating retinal ganglion cells: effects of intravitreal neurotrophic supply.
Investigative ophthalmology & visual science Dec, 2003 | Pubmed ID: 14638736
Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity.
Journal of neurochemistry Dec, 2003 | Pubmed ID: 14713297
CNTF promotes survival of retinal ganglion cells after induction of ocular hypertension in rats: the possible involvement of STAT3 pathway.
The European journal of neuroscience Jan, 2004 | Pubmed ID: 14725620
Regulation of caspase activation in axotomized retinal ganglion cells.
Molecular and cellular neurosciences Mar, 2004 | Pubmed ID: 15033167
Modulation of calcium/calmodulin kinase-II provides partial neuroprotection against beta-amyloid peptide toxicity.
The European journal of neuroscience Apr, 2004 | Pubmed ID: 15090032
Increasing scans per examination improves the reproducibility on retinal nerve fiber layer measurements by optical coherence tomography.
Optometry and vision science : official publication of the American Academy of Optometry Apr, 2004 | Pubmed ID: 15097769
Synergistic effect of Nogo-neutralizing antibody IN-1 and ciliary neurotrophic factor on axonal regeneration in adult rodent visual systems.
Journal of neurotrauma May, 2004 | Pubmed ID: 15165369
Retinal nerve fiber loss in high- and normal-tension glaucoma by optical coherence tomography.
Optometry and vision science : official publication of the American Academy of Optometry May, 2004 | Pubmed ID: 15181362
Lithium chloride reinforces the regeneration-promoting effect of chondroitinase ABC on rubrospinal neurons after spinal cord injury.
Journal of neurotrauma Jul, 2004 | Pubmed ID: 15307905
Intravitreal transplants of Schwann cells and fibroblasts promote the survival of axotomized retinal ganglion cells in rats.
Brain research Dec, 2004 | Pubmed ID: 15533316
Involvement of cAMP in neuronal survival and axonal regeneration.
Anatomical science international Dec, 2004 | Pubmed ID: 15633459
CNTF and BDNF have similar effects on retinal ganglion cell survival but differential effects on nitric oxide synthase expression soon after optic nerve injury.
Investigative ophthalmology & visual science Apr, 2005 | Pubmed ID: 15790921
Electroacupuncture provides a new approach to neuroprotection in rats with induced glaucoma.
Journal of alternative and complementary medicine (New York, N.Y.) Apr, 2005 | Pubmed ID: 15865499
Different optic nerve injury sites result in different responses of retinal ganglion cells to brain-derived neurotrophic factor but not neurotrophin-4/5.
Brain research Jun, 2005 | Pubmed ID: 15904902
Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity.
Experimental gerontology Aug-Sep, 2005 | Pubmed ID: 16139464
Transgenic mice expressing Cre-recombinase specifically in retinal rod bipolar neurons.
Investigative ophthalmology & visual science Oct, 2005 | Pubmed ID: 16186328
Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice.
Diabetes Nov, 2005 | Pubmed ID: 16249434
Developmental changes of nitric oxide synthase expression in the rat hypothalamoneurohypophyseal system.
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology Jan, 2006 | Pubmed ID: 16342209
Light delays synaptic deafferentation and potentiates the survival of axotomized retinal ganglion cells.
Neuroscience letters Mar, 2006 | Pubmed ID: 16352397
Beta-amyloid peptides induces neuronal apoptosis via a mechanism independent of unfolded protein responses.
Apoptosis : an international journal on programmed cell death May, 2006 | Pubmed ID: 16532272
Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2006 | Pubmed ID: 16549776
Age-related reexpression of p75 in axotomized motoneurons.
Neuroreport May, 2006 | Pubmed ID: 16641674
Cytoprotective effects of Lycium barbarum against reducing stress on endoplasmic reticulum.
International journal of molecular medicine Jun, 2006 | Pubmed ID: 16685430
Characterization and localization of the supraorbital and frontal exits of the supraorbital nerve in Chinese: an anatomic study.
Ophthalmic plastic and reconstructive surgery May-Jun, 2006 | Pubmed ID: 16714932
Melanopsin-expressing retinal ganglion cells are more injury-resistant in a chronic ocular hypertension model.
Investigative ophthalmology & visual science Jul, 2006 | Pubmed ID: 16799038
Graded ephrin-A2 expression in the developing hamster superior colliculus.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale Aug, 2006 | Pubmed ID: 16850319
Expression of nicotinamide adenine dinucleotide phosphate-diaphorase in the retina of postnatal golden hamsters deprived of light stimulation.
Neuroscience letters Sep, 2006 | Pubmed ID: 16854523
Changes of retinal functions following the induction of ocular hypertension in rats using argon laser photocoagulation.
Clinical & experimental ophthalmology Aug, 2006 | Pubmed ID: 16925706
The response of magnocellular neurons of the hypothalamo-neurohyphyseal system to hypophysectomy, nitric oxide synthase expression as well as survival and regeneration in developing vs. adult rats.
Brain research Oct, 2006 | Pubmed ID: 16949057
A suprachiasmatic nucleus projecting retinal ganglion cell exhibits an unusually large dendritic field in the hamster.
Neuroreport Oct, 2006 | Pubmed ID: 16957590
LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury.
Molecular and cellular neurosciences Nov, 2006 | Pubmed ID: 17011208
Neuroprotective effects of Lycium barbarum Lynn on protecting retinal ganglion cells in an ocular hypertension model of glaucoma.
Experimental neurology Jan, 2007 | Pubmed ID: 17045262
Nano hemostat solution: immediate hemostasis at the nanoscale.
Nanomedicine : nanotechnology, biology, and medicine Dec, 2006 | Pubmed ID: 17292144
Corticosteroid decreases subventricular zone cell proliferation, which could be reversed by paroxetine.
Restorative neurology and neuroscience , 2007 | Pubmed ID: 17473392
New polysaccharide from Nerium indicum protects neurons via stress kinase signaling pathway.
Brain research Jun, 2007 | Pubmed ID: 17475226
Up-regulated endogenous erythropoietin/erythropoietin receptor system and exogenous erythropoietin rescue retinal ganglion cells after chronic ocular hypertension.
Cellular and molecular neurobiology Feb, 2008 | Pubmed ID: 17554621
Characterizing the neuroprotective effects of alkaline extract of Lycium barbarum on beta-amyloid peptide neurotoxicity.
Brain research Jul, 2007 | Pubmed ID: 17568570
A subpopulation of reactive astrocytes at affected neuronal perikarya after hypophysectomy in adult rats.
Brain research Jul, 2007 | Pubmed ID: 17573051
Characterization of the effects of anti-aging medicine Fructus lycii on beta-amyloid peptide neurotoxicity.
International journal of molecular medicine Aug, 2007 | Pubmed ID: 17611646
Modulation of the suppressive effect of corticosterone on adult rat hippocampal cell proliferation by paroxetine.
Neuroscience bulletin May, 2007 | Pubmed ID: 17612590
Differential activation of c-fos immunoreactivity after hypophysectomy in developing and adult rats.
Anatomical record (Hoboken, N.J. : 2007) Sep, 2007 | Pubmed ID: 17661378
Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far?
Cellular and molecular neurobiology Aug, 2008 | Pubmed ID: 17710531
A neuroprotective herbal mixture inhibits caspase-3-independent apoptosis in retinal ganglion cells.
Cellular and molecular neurobiology Jan, 2008 | Pubmed ID: 17710535
Chemotactic effect of ciliary neurotrophic factor on macrophages in retinal ganglion cell survival and axonal regeneration.
Investigative ophthalmology & visual science Sep, 2007 | Pubmed ID: 17724215
Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury.
Experimental eye research Nov, 2007 | Pubmed ID: 17727843
LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis.
Nature medicine Oct, 2007 | Pubmed ID: 17906634
Reknitting the injured spinal cord by self-assembling peptide nanofiber scaffold.
Nanomedicine : nanotechnology, biology, and medicine Dec, 2007 | Pubmed ID: 17964861
Evaluation of the visual system in a rat model of chronic glaucoma using manganese-enhanced magnetic resonance imaging.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2007 | Pubmed ID: 18001890
Diffusion tensor MR study of optic nerve degeneration in glaucoma.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2007 | Pubmed ID: 18002956
Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum.
Brain research Jan, 2008 | Pubmed ID: 18083148
Molecular cloning and characterization of the zebrafish (Danio rerio) telomerase catalytic subunit (telomerase reverse transcriptase, TERT).
Journal of molecular neuroscience : MN , 2008 | Pubmed ID: 18157659
Evaluation of the retina and optic nerve in a rat model of chronic glaucoma using in vivo manganese-enhanced magnetic resonance imaging.
NeuroImage Apr, 2008 | Pubmed ID: 18272401
Blocking LINGO-1 function promotes retinal ganglion cell survival following ocular hypertension and optic nerve transection.
Investigative ophthalmology & visual science Mar, 2008 | Pubmed ID: 18326721
Surgical anatomy of the Chinese orbit.
Ophthalmic plastic and reconstructive surgery Mar-Apr, 2008 | Pubmed ID: 18356720
Enhanced survival of melanopsin-expressing retinal ganglion cells after injury is associated with the PI3 K/Akt pathway.
Cellular and molecular neurobiology Dec, 2008 | Pubmed ID: 18512147
GD-DTPA enhanced MRI of ocular transport in a rat model of chronic glaucoma.
Experimental eye research Oct, 2008 | Pubmed ID: 18639546
Effect of lutein on retinal neurons and oxidative stress in a model of acute retinal ischemia/reperfusion.
Investigative ophthalmology & visual science Feb, 2009 | Pubmed ID: 18936152
Proton magnetic resonance spectroscopy revealed choline reduction in the visual cortex in an experimental model of chronic glaucoma.
Experimental eye research Jan, 2009 | Pubmed ID: 18992243
Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research.
Neurotoxicology Jan, 2009 | Pubmed ID: 19056420
Dynamic contrast-enhanced MRI of ocular biotransport in normal and hypertensive eyes.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2008 | Pubmed ID: 19162786
Synaptic degeneration of retinal ganglion cells in a rat ocular hypertension glaucoma model.
Cellular and molecular neurobiology Jun, 2009 | Pubmed ID: 19172389
Intracerebroventricular infusion of cytosine-arabinoside causes prepulse inhibition disruption.
Neuroreport Mar, 2009 | Pubmed ID: 19218868
Post pressure response of skin blood flowmotions in anesthetized rats with spinal cord injury.
Microvascular research Jun, 2009 | Pubmed ID: 19328816
Low molecular weight Abeta induces collapse of endoplasmic reticulum.
Molecular and cellular neurosciences May, 2009 | Pubmed ID: 19386229
The selective vulnerability of retinal ganglion cells in rat chronic ocular hypertension model at early phase.
Cellular and molecular neurobiology Dec, 2009 | Pubmed ID: 19396539
Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons.
Cellular and molecular neurobiology Dec, 2009 | Pubmed ID: 19499323
Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model.
Journal of ocular biology, diseases, and informatics Jun, 2009 | Pubmed ID: 19672466
Visual response properties of Y cells in the detached feline retina.
Investigative ophthalmology & visual science Feb, 2010 | Pubmed ID: 19797207
Anti-aging herbal medicine--how and why can they be used in aging-associated neurodegenerative diseases?
Ageing research reviews Jul, 2010 | Pubmed ID: 19833234
GAP-43 expression correlates with spinal motoneuron regeneration following root avulsion.
Journal of brachial plexus and peripheral nerve injury , 2009 | Pubmed ID: 19852861
Modulation of neuroimmune responses on glia in the central nervous system: implication in therapeutic intervention against neuroinflammation.
Cellular & molecular immunology Oct, 2009 | Pubmed ID: 19887044
Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight β-amyloid peptide.
Journal of cellular and molecular medicine Feb, 2011 | Pubmed ID: 20015199
Erratum: Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model.
Journal of ocular biology, diseases, and informatics Sep, 2009 | Pubmed ID: 20046845
Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma.
Cellular & molecular immunology Jan, 2010 | Pubmed ID: 20081877
Induction of c-Jun phosphorylation in spinal motoneurons in neonatal and adult rats following axonal injury.
Brain research Mar, 2010 | Pubmed ID: 20096669
Dietary restriction and brain health.
Neuroscience bulletin Feb, 2010 | Pubmed ID: 20101273
Generation of human induced pluripotent stem cells from umbilical cord matrix and amniotic membrane mesenchymal cells.
The Journal of biological chemistry Apr, 2010 | Pubmed ID: 20139068
Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons.
Journal of Alzheimer's disease : JAD , 2010 | Pubmed ID: 20157238
Up-regulation of crystallins is involved in the neuroprotective effect of wolfberry on survival of retinal ganglion cells in rat ocular hypertension model.
Journal of cellular biochemistry May, 2010 | Pubmed ID: 20336662
LINGO-1 negatively regulates TrkB phosphorylation after ocular hypertension.
The European journal of neuroscience Mar, 2010 | Pubmed ID: 20377621
Roles of paroxetine and corticosterone on adult mammalian ciliary body cell proliferation.
Chinese medical journal May, 2010 | Pubmed ID: 20529586
In vivo retinotopic mapping of superior colliculus using manganese-enhanced magnetic resonance imaging.
NeuroImage Jan, 2011 | Pubmed ID: 20633657
Co-expression of GAP-43 and nNOS in avulsed motoneurons and their potential role for motoneuron regeneration.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society Dec, 2010 | Pubmed ID: 20667480
Adiponectin protects rat hippocampal neurons against excitotoxicity.
Age (Dordrecht, Netherlands) Jun, 2011 | Pubmed ID: 20842535
Reproduction: a new venue for studying function of adult neurogenesis?
Cell transplantation , 2011 | Pubmed ID: 20887675
Adult hippocampal neurogenesis: a possible way how physical exercise counteracts stress.
Cell transplantation , 2011 | Pubmed ID: 20887683
Effect of corticosterone and paroxetine on masculine mating behavior: possible involvement of neurogenesis.
The journal of sexual medicine May, 2011 | Pubmed ID: 20955318
Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal mongolian gerbil (Meriones unguiculatus).
Cell transplantation , 2011 | Pubmed ID: 21054936
In vivo MRI study of the visual system in normal, developing and injured rodent brains.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2010 | Pubmed ID: 21097319
Long-term in vivo imaging and measurement of dendritic shrinkage of retinal ganglion cells.
Investigative ophthalmology & visual science Mar, 2011 | Pubmed ID: 21245394
Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury.
PloS one , 2011 | Pubmed ID: 21298100
Caveolin-1 promote astroglial differentiation of neural stem/progenitor cells through modulating Notch1/NICD and Hes1 expressions.
Biochemical and biophysical research communications Apr, 2011 | Pubmed ID: 21414292
Learning new color names produces rapid increase in gray matter in the intact adult human cortex.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2011 | Pubmed ID: 21464316
Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia.
Chinese medicine , 2011 | Pubmed ID: 21513513
Y-like retinal ganglion cells innervate the dorsal raphe nucleus in the Mongolian gerbil (Meriones unguiculatus).
PloS one , 2011 | Pubmed ID: 21552551
Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina?
Age (Dordrecht, Netherlands) May, 2011 | Pubmed ID: 21559868
The expression patterns of Nogo-A, myelin associated glycoprotein and oligodendrocyte myelin glycoprotein in the retina after ocular hypertension: the expression of myelin proteins in the retina in glaucoma.
Neurochemical research Nov, 2011 | Pubmed ID: 21643729
Caveolin-1 inhibits oligodendroglial differentiation of neural stem/progenitor cells through modulating β-catenin expression.
Neurochemistry international Aug, 2011 | Pubmed ID: 21693146
Soluble NgR fusion protein modulates the proliferation of neural progenitor cells via the Notch pathway.
Neurochemical research Dec, 2011 | Pubmed ID: 21822922
Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway.
PloS one , 2011 | Pubmed ID: 21826216
Effect of inner retinal dysfunction on slow double-stimulation multifocal electroretinogram.
The British journal of ophthalmology Nov, 2011 | Pubmed ID: 21849350
Luminance-modulated adaptation in the global flash mfERG: a preliminary study of early retinal functional changes in high-risk glaucoma patients.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Feb, 2012 | Pubmed ID: 21881844
Hippocampal neurogenesis and dendritic plasticity support running-improved spatial learning and depression-like behaviour in stressed rats.
PloS one , 2011 | Pubmed ID: 21935393
Soluble Nogo-66 receptor prevents synaptic dysfunction and rescues retinal ganglion cell loss in chronic glaucoma.
Investigative ophthalmology & visual science Oct, 2011 | Pubmed ID: 21948553
Elevated blood pressure aggravates intracerebral hemorrhage-induced brain injury.
Journal of neurotrauma Dec, 2011 | Pubmed ID: 21988112
Endoplasmic Reticulum Stress Induces Tau Pathology and Forms a Vicious Cycle: Implication in Alzheimer's Disease Pathogenesis.
Journal of Alzheimer's disease : JAD Nov, 2011 | Pubmed ID: 22101233
Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation.
Journal of ethnopharmacology Jan, 2012 | Pubmed ID: 22138659
Neuroprotection provided by dietary restriction in rats is further enhanced by reducing glucocortocoids.
Neurobiology of aging Jan, 2012 | Pubmed ID: 22226488
Decreased c-Jun expression correlates with impaired spinal motoneuron regeneration in aged mice following sciatic nerve crush.
Experimental gerontology Feb, 2012 | Pubmed ID: 22382134
Tin Fung Chan1,
Kin Chiu1,
Carmen Ka Ming Lok1,
Wing Lau Ho1,
Kwok-Fai So1,2,3,
Raymond Chuen-Chung Chang1,2,3
1Laboratory of Neurodegenerative Diseases, Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong,
2Research Centre of Heart, Brain, Hormone and Healthy Aging, LKS Faculty of Medicine, The University of Hong Kong,
3State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong