Kwok-Fai So

Laboratory of Neurodegenerative Diseases, The University of Hong Kong - HKU

Affiliated withThe University of Hong Kong - HKU The University of Hong Kong

Research Area

BiologyNeuroscience

Biography

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JoVE Journal Publications

ArticleTotal : 5	Year
Publication title	2007
Publication title	2007
Publication title	2007
Publication title	2008
Publication title	2012

Other Publications

Article	Year
Enhanced survival and regeneration of axotomized retinal ganglion cells by a mixture of herbal extracts. Journal of neurotrauma\| PubMed ID: 11939504	2002
Postnatal development of nicotinamide adenine dinucleotide phosphate-diaphorase-positive neurons in the retina of the golden hamster. The Journal of comparative neurology\| PubMed ID: 11954033	2002
Expression of trkA, trkB, and trkC in injured and regenerating retinal ganglion cells of adult rats. Investigative ophthalmology & visual science\| PubMed ID: 12037005	2002
Development of the regenerative capacity of postnatal axotomized rat spinal motoneurons. Neuroreport\| PubMed ID: 12060811	2002
Total retinal nitric oxide production is increased in intraocular pressure-elevated rats. Experimental eye research\| PubMed ID: 12387787	2002
Retinal nerve fiber layer measurement of the Hong Kong chinese population by optical coherence tomography. Journal of glaucoma\| PubMed ID: 12483090	2002
Axonal regeneration of retinal ganglion cells after optic nerve pre-lesions and attachment of normal or pre-degenerated peripheral nerve grafts. Visual neuroscience\| PubMed ID: 12507332	2002
Retinal nerve fiber layer measurement by optical coherence tomography in glaucoma suspects with short-wavelength perimetry abnormalities. Journal of glaucoma\| PubMed ID: 12567111	2003
Intraocular elevation of cyclic AMP potentiates ciliary neurotrophic factor-induced regeneration of adult rat retinal ganglion cell axons. Molecular and cellular neurosciences\| PubMed ID: 12595238	2003
Axotomy induces cytochrome c release in retinal ganglion cells. Neuroreport\| PubMed ID: 12598746	2003
A morphometric study of optic axons regenerated in a sciatic nerve graft of adult rats. Restorative neurology and neuroscience\| PubMed ID: 12671213	2000
Inhibition of caspases promotes long-term survival and reinnervation by axotomized spinal motoneurons of denervated muscle in newborn rats. Experimental neurology\| PubMed ID: 12781992	2003
Retinal nerve fiber loss pattern in high-tension glaucoma by optical coherence tomography. Journal of glaucoma\| PubMed ID: 12782845	2003
Axonal regeneration of Clarke's neurons beyond the spinal cord injury scar after treatment with chondroitinase ABC. Experimental neurology\| PubMed ID: 12821386	2003
Inflammatory response associated with axonal injury to spinal motoneurons in newborn rats. Developmental neuroscience\| PubMed ID: 12876433	2003
Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity. The Journal of biological chemistry\| PubMed ID: 12975376	2003
c-Jun expression in surviving and regenerating retinal ganglion cells: effects of intravitreal neurotrophic supply. Investigative ophthalmology & visual science\| PubMed ID: 14638736	2003
Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity. Journal of neurochemistry\| PubMed ID: 14713297	2003
CNTF promotes survival of retinal ganglion cells after induction of ocular hypertension in rats: the possible involvement of STAT3 pathway. The European journal of neuroscience\| PubMed ID: 14725620	2004
Regulation of caspase activation in axotomized retinal ganglion cells. Molecular and cellular neurosciences\| PubMed ID: 15033167	2004
Modulation of calcium/calmodulin kinase-II provides partial neuroprotection against beta-amyloid peptide toxicity. The European journal of neuroscience\| PubMed ID: 15090032	2004
Increasing scans per examination improves the reproducibility on retinal nerve fiber layer measurements by optical coherence tomography. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 15097769	2004
Synergistic effect of Nogo-neutralizing antibody IN-1 and ciliary neurotrophic factor on axonal regeneration in adult rodent visual systems. Journal of neurotrauma\| PubMed ID: 15165369	2004
Retinal nerve fiber loss in high- and normal-tension glaucoma by optical coherence tomography. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 15181362	2004
Lithium chloride reinforces the regeneration-promoting effect of chondroitinase ABC on rubrospinal neurons after spinal cord injury. Journal of neurotrauma\| PubMed ID: 15307905	2004
Intravitreal transplants of Schwann cells and fibroblasts promote the survival of axotomized retinal ganglion cells in rats. Brain research\| PubMed ID: 15533316	2004
Involvement of cAMP in neuronal survival and axonal regeneration. Anatomical science international\| PubMed ID: 15633459	2004
CNTF and BDNF have similar effects on retinal ganglion cell survival but differential effects on nitric oxide synthase expression soon after optic nerve injury. Investigative ophthalmology & visual science\| PubMed ID: 15790921	2005
Electroacupuncture provides a new approach to neuroprotection in rats with induced glaucoma. Journal of alternative and complementary medicine (New York, N.Y.)\| PubMed ID: 15865499	2005
Different optic nerve injury sites result in different responses of retinal ganglion cells to brain-derived neurotrophic factor but not neurotrophin-4/5. Brain research\| PubMed ID: 15904902	2005
Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity. Experimental gerontology\| PubMed ID: 16139464	2005
Transgenic mice expressing Cre-recombinase specifically in retinal rod bipolar neurons. Investigative ophthalmology & visual science\| PubMed ID: 16186328	2005
Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice. Diabetes\| PubMed ID: 16249434	2005
Developmental changes of nitric oxide synthase expression in the rat hypothalamoneurohypophyseal system. The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology\| PubMed ID: 16342209	2006
Light delays synaptic deafferentation and potentiates the survival of axotomized retinal ganglion cells. Neuroscience letters\| PubMed ID: 16352397	2006
Beta-amyloid peptides induces neuronal apoptosis via a mechanism independent of unfolded protein responses. Apoptosis : an international journal on programmed cell death\| PubMed ID: 16532272	2006
Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16549776	2006
Age-related reexpression of p75 in axotomized motoneurons. Neuroreport\| PubMed ID: 16641674	2006
Cytoprotective effects of Lycium barbarum against reducing stress on endoplasmic reticulum. International journal of molecular medicine\| PubMed ID: 16685430	2006
Characterization and localization of the supraorbital and frontal exits of the supraorbital nerve in Chinese: an anatomic study. Ophthalmic plastic and reconstructive surgery\| PubMed ID: 16714932	2006
Melanopsin-expressing retinal ganglion cells are more injury-resistant in a chronic ocular hypertension model. Investigative ophthalmology & visual science\| PubMed ID: 16799038	2006
Graded ephrin-A2 expression in the developing hamster superior colliculus. Experimental brain research. Experimentelle Hirnforschung. ExpÃ©rimentation cÃ©rÃ©brale\| PubMed ID: 16850319	2006
Expression of nicotinamide adenine dinucleotide phosphate-diaphorase in the retina of postnatal golden hamsters deprived of light stimulation. Neuroscience letters\| PubMed ID: 16854523	2006
Changes of retinal functions following the induction of ocular hypertension in rats using argon laser photocoagulation. Clinical & experimental ophthalmology\| PubMed ID: 16925706	2006
The response of magnocellular neurons of the hypothalamo-neurohyphyseal system to hypophysectomy, nitric oxide synthase expression as well as survival and regeneration in developing vs. adul... Brain research\| PubMed ID: 16949057	2006
A suprachiasmatic nucleus projecting retinal ganglion cell exhibits an unusually large dendritic field in the hamster. Neuroreport\| PubMed ID: 16957590	2006
LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury. Molecular and cellular neurosciences\| PubMed ID: 17011208	2006
Neuroprotective effects of Lycium barbarum Lynn on protecting retinal ganglion cells in an ocular hypertension model of glaucoma. Experimental neurology\| PubMed ID: 17045262	2007
Nano hemostat solution: immediate hemostasis at the nanoscale. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 17292144	2006
Corticosteroid decreases subventricular zone cell proliferation, which could be reversed by paroxetine. Restorative neurology and neuroscience\| PubMed ID: 17473392	2007
New polysaccharide from Nerium indicum protects neurons via stress kinase signaling pathway. Brain research\| PubMed ID: 17475226	2007
Up-regulated endogenous erythropoietin/erythropoietin receptor system and exogenous erythropoietin rescue retinal ganglion cells after chronic ocular hypertension. Cellular and molecular neurobiology\| PubMed ID: 17554621	2008
Characterizing the neuroprotective effects of alkaline extract of Lycium barbarum on beta-amyloid peptide neurotoxicity. Brain research\| PubMed ID: 17568570	2007
A subpopulation of reactive astrocytes at affected neuronal perikarya after hypophysectomy in adult rats. Brain research\| PubMed ID: 17573051	2007
Characterization of the effects of anti-aging medicine Fructus lycii on beta-amyloid peptide neurotoxicity. International journal of molecular medicine\| PubMed ID: 17611646	2007
Modulation of the suppressive effect of corticosterone on adult rat hippocampal cell proliferation by paroxetine. Neuroscience bulletin\| PubMed ID: 17612590	2007
Differential activation of c-fos immunoreactivity after hypophysectomy in developing and adult rats. Anatomical record (Hoboken, N.J. : 2007)\| PubMed ID: 17661378	2007
Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far? Cellular and molecular neurobiology\| PubMed ID: 17710531	2008
A neuroprotective herbal mixture inhibits caspase-3-independent apoptosis in retinal ganglion cells. Cellular and molecular neurobiology\| PubMed ID: 17710535	2008
Chemotactic effect of ciliary neurotrophic factor on macrophages in retinal ganglion cell survival and axonal regeneration. Investigative ophthalmology & visual science\| PubMed ID: 17724215	2007
Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury. Experimental eye research\| PubMed ID: 17727843	2007
LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. Nature medicine\| PubMed ID: 17906634	2007
Reknitting the injured spinal cord by self-assembling peptide nanofiber scaffold. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 17964861	2007
Evaluation of the visual system in a rat model of chronic glaucoma using manganese-enhanced magnetic resonance imaging. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 18001890	2007
Diffusion tensor MR study of optic nerve degeneration in glaucoma. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 18002956	2007
Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum. Brain research\| PubMed ID: 18083148	2008
Molecular cloning and characterization of the zebrafish (Danio rerio) telomerase catalytic subunit (telomerase reverse transcriptase, TERT). Journal of molecular neuroscience : MN\| PubMed ID: 18157659	2008
Evaluation of the retina and optic nerve in a rat model of chronic glaucoma using in vivo manganese-enhanced magnetic resonance imaging. NeuroImage\| PubMed ID: 18272401	2008
Blocking LINGO-1 function promotes retinal ganglion cell survival following ocular hypertension and optic nerve transection. Investigative ophthalmology & visual science\| PubMed ID: 18326721	2008
Surgical anatomy of the Chinese orbit. Ophthalmic plastic and reconstructive surgery\| PubMed ID: 18356720	2008
Enhanced survival of melanopsin-expressing retinal ganglion cells after injury is associated with the PI3 K/Akt pathway. Cellular and molecular neurobiology\| PubMed ID: 18512147	2008
GD-DTPA enhanced MRI of ocular transport in a rat model of chronic glaucoma. Experimental eye research\| PubMed ID: 18639546	2008
Effect of lutein on retinal neurons and oxidative stress in a model of acute retinal ischemia/reperfusion. Investigative ophthalmology & visual science\| PubMed ID: 18936152	2009
Proton magnetic resonance spectroscopy revealed choline reduction in the visual cortex in an experimental model of chronic glaucoma. Experimental eye research\| PubMed ID: 18992243	2009
Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research. Neurotoxicology\| PubMed ID: 19056420	2009
Dynamic contrast-enhanced MRI of ocular biotransport in normal and hypertensive eyes. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 19162786	2008
Synaptic degeneration of retinal ganglion cells in a rat ocular hypertension glaucoma model. Cellular and molecular neurobiology\| PubMed ID: 19172389	2009
Intracerebroventricular infusion of cytosine-arabinoside causes prepulse inhibition disruption. Neuroreport\| PubMed ID: 19218868	2009
Post pressure response of skin blood flowmotions in anesthetized rats with spinal cord injury. Microvascular research\| PubMed ID: 19328816	2009
Low molecular weight Abeta induces collapse of endoplasmic reticulum. Molecular and cellular neurosciences\| PubMed ID: 19386229	2009
The selective vulnerability of retinal ganglion cells in rat chronic ocular hypertension model at early phase. Cellular and molecular neurobiology\| PubMed ID: 19396539	2009
Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons. Cellular and molecular neurobiology\| PubMed ID: 19499323	2009
Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model. Journal of ocular biology, diseases, and informatics\| PubMed ID: 19672466	2009
Visual response properties of Y cells in the detached feline retina. Investigative ophthalmology & visual science\| PubMed ID: 19797207	2010
Anti-aging herbal medicine--how and why can they be used in aging-associated neurodegenerative diseases? Ageing research reviews\| PubMed ID: 19833234	2010
GAP-43 expression correlates with spinal motoneuron regeneration following root avulsion. Journal of brachial plexus and peripheral nerve injury\| PubMed ID: 19852861	2009
Modulation of neuroimmune responses on glia in the central nervous system: implication in therapeutic intervention against neuroinflammation. Cellular & molecular immunology\| PubMed ID: 19887044	2009
Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight Î²-amyloid peptide. Journal of cellular and molecular medicine\| PubMed ID: 20015199	2011
Erratum: Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model. Journal of ocular biology, diseases, and informatics\| PubMed ID: 20046845	2009
Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma. Cellular & molecular immunology\| PubMed ID: 20081877	2010
Induction of c-Jun phosphorylation in spinal motoneurons in neonatal and adult rats following axonal injury. Brain research\| PubMed ID: 20096669	2010
Dietary restriction and brain health. Neuroscience bulletin\| PubMed ID: 20101273	2010
Generation of human induced pluripotent stem cells from umbilical cord matrix and amniotic membrane mesenchymal cells. The Journal of biological chemistry\| PubMed ID: 20139068	2010
Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons. Journal of Alzheimer's disease : JAD\| PubMed ID: 20157238	2010
Up-regulation of crystallins is involved in the neuroprotective effect of wolfberry on survival of retinal ganglion cells in rat ocular hypertension model. Journal of cellular biochemistry\| PubMed ID: 20336662	2010
LINGO-1 negatively regulates TrkB phosphorylation after ocular hypertension. The European journal of neuroscience\| PubMed ID: 20377621	2010
Roles of paroxetine and corticosterone on adult mammalian ciliary body cell proliferation. Chinese medical journal\| PubMed ID: 20529586	2010
In vivo retinotopic mapping of superior colliculus using manganese-enhanced magnetic resonance imaging. NeuroImage\| PubMed ID: 20633657	2011
Co-expression of GAP-43 and nNOS in avulsed motoneurons and their potential role for motoneuron regeneration. Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society\| PubMed ID: 20667480	2010
Adiponectin protects rat hippocampal neurons against excitotoxicity. Age (Dordrecht, Netherlands)\| PubMed ID: 20842535	2011
Reproduction: a new venue for studying function of adult neurogenesis? Cell transplantation\| PubMed ID: 20887675	2011
Adult hippocampal neurogenesis: a possible way how physical exercise counteracts stress. Cell transplantation\| PubMed ID: 20887683	2011
Effect of corticosterone and paroxetine on masculine mating behavior: possible involvement of neurogenesis. The journal of sexual medicine\| PubMed ID: 20955318	2011
Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal mongolian gerbil (Meriones unguiculatus). Cell transplantation\| PubMed ID: 21054936	2011
In vivo MRI study of the visual system in normal, developing and injured rodent brains. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 21097319	2010
Long-term in vivo imaging and measurement of dendritic shrinkage of retinal ganglion cells. Investigative ophthalmology & visual science\| PubMed ID: 21245394	2011
Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury. PloS one\| PubMed ID: 21298100	2011
Caveolin-1 promote astroglial differentiation of neural stem/progenitor cells through modulating Notch1/NICD and Hes1 expressions. Biochemical and biophysical research communications\| PubMed ID: 21414292	2011
Learning new color names produces rapid increase in gray matter in the intact adult human cortex. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21464316	2011
Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia. Chinese medicine\| PubMed ID: 21513513	2011
Y-like retinal ganglion cells innervate the dorsal raphe nucleus in the Mongolian gerbil (Meriones unguiculatus). PloS one\| PubMed ID: 21552551	2011
Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina? Age (Dordrecht, Netherlands)\| PubMed ID: 21559868	2011
The expression patterns of Nogo-A, myelin associated glycoprotein and oligodendrocyte myelin glycoprotein in the retina after ocular hypertension: the expression of myelin proteins in the re... Neurochemical research\| PubMed ID: 21643729	2011
Caveolin-1 inhibits oligodendroglial differentiation of neural stem/progenitor cells through modulating Î²-catenin expression. Neurochemistry international\| PubMed ID: 21693146	2011
Soluble NgR fusion protein modulates the proliferation of neural progenitor cells via the Notch pathway. Neurochemical research\| PubMed ID: 21822922	2011
Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway. PloS one\| PubMed ID: 21826216	2011
Effect of inner retinal dysfunction on slow double-stimulation multifocal electroretinogram. The British journal of ophthalmology\| PubMed ID: 21849350	2011
Luminance-modulated adaptation in the global flash mfERG: a preliminary study of early retinal functional changes in high-risk glaucoma patients. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fÃ¼r klinische und experimentelle Ophthalmologie\| PubMed ID: 21881844	2012
Hippocampal neurogenesis and dendritic plasticity support running-improved spatial learning and depression-like behaviour in stressed rats. PloS one\| PubMed ID: 21935393	2011
Soluble Nogo-66 receptor prevents synaptic dysfunction and rescues retinal ganglion cell loss in chronic glaucoma. Investigative ophthalmology & visual science\| PubMed ID: 21948553	2011
Elevated blood pressure aggravates intracerebral hemorrhage-induced brain injury. Journal of neurotrauma\| PubMed ID: 21988112	2011
Endoplasmic Reticulum Stress Induces Tau Pathology and Forms a Vicious Cycle: Implication in Alzheimer's Disease Pathogenesis. Journal of Alzheimer's disease : JAD\| PubMed ID: 22101233	2011
Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation. Journal of ethnopharmacology\| PubMed ID: 22138659	2012
Neuroprotection provided by dietary restriction in rats is further enhanced by reducing glucocortocoids. Neurobiology of aging\| PubMed ID: 22226488	2012
Decreased c-Jun expression correlates with impaired spinal motoneuron regeneration in aged mice following sciatic nerve crush. Experimental gerontology\| PubMed ID: 22382134	2012