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Department of Surgical Oncology
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Polyfunctionality of a DKK1 self-antigen-specific CD8(+) T lymphocyte clone in lung cancer.
Cancer immunology, immunotherapy : CII Aug, 2011 | Pubmed ID: 21681374
Stimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotype.
PloS one , 2012 | Pubmed ID: 22859966
The WT hemochromatosis protein HFE inhibits CD8⁺ T-lymphocyte activation.
European journal of immunology Jun, 2014 | Pubmed ID: 24643698
Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma.
Cancer biology & medicine Dec, 2014 | Pubmed ID: 25610709
T lymphocyte-derived TNF and IFN-γ repress HFE expression in cancer cells.
Molecular immunology Jun, 2015 | Pubmed ID: 25700349
Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma.
Oncoimmunology Oct, 2014 | Pubmed ID: 25941608
Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research Jul, 2015 | Pubmed ID: 26025561
Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy.
Seminars in oncology Aug, 2015 | Pubmed ID: 26320064
Raising the bar: optimizing combinations of targeted therapy and immunotherapy.
Annals of translational medicine Oct, 2015 | Pubmed ID: 26605318
University of Texas MD Anderson Cancer Center
Alexandre Reuben*,1,
Vancheswaran Gopalakrishnan*,1,
Heidi E. Wagner3,
Christine N. Spencer2,
Jacob Austin-Breneman1,
Hong Jiang1,
Zachary A. Cooper1,
Jennifer A. Wargo1
1Department of Surgical Oncology, University of Texas MD Anderson Cancer Center,
2Department of Genomic Medicine, University of Texas MD Anderson Cancer Center,
3Department of Pathology and Institutional Tissue Bank, University of Texas MD Anderson Cancer Center
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