Michael Shaw

Mining the Plasmodium genome database to define organellar function: what does the apicoplast do?

Actin filament turnover removes bundles from Drosophila bristle cells.

Cysteine and serine protease inhibitors block intracellular development and disrupt the secretory pathway of Toxoplasma gondii.

Recurrent bleeding from peptic ulcer associated with adherent clot: a randomized study comparing endoscopic treatment with medical therapy.

Introduction of Aedes albopictus (Skuse) in southern California and potential for its establishment.

Identifying patients with gastroesophageal reflux disease: validation of a practical screening tool.

Isolation and characterization of TgVP1, a type I vacuolar H+-translocating pyrophosphatase from Toxoplasma gondii. The dynamics of its subcellular localization and the cellular effects of a diphosphonate inhibitor.

Reappearance and global spread of variants of influenza B/Victoria/2/87 lineage viruses in the 2000-2001 and 2001-2002 seasons.

Cell invasion by Theileria sporozoites.

Azadirachtin disrupts formation of organised microtubule arrays during microgametogenesis of Plasmodium berghei.

Clinical effectiveness of laparoscopic fundoplication in a U.S. community.

A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity.

Improving health-related quality of life in gastro-oesophageal reflux disease.

Hybridization between Brassica napus and B. rapa on a national scale in the United Kingdom.

Has Aedes albopictus established in California?

Screening for Barrett's esophagus in colonoscopy patients with and without heartburn.

Self-selection and use patterns of over-the-counter omeprazole for frequent heartburn.

Coalignment of plasma membrane channels and protrusions (fibripositors) specifies the parallelism of tendon.

Reassortment and evolution of current human influenza A and B viruses.

The role of lithium clinics in the treatment of bipolar disorder.

Phosphorylated BRCA1 is predominantly located in the nucleus and mitochondria.

Preparation of kinase-biased compounds in the search for lead inhibitors of kinase targets.

Isolation and characterization of avian influenza viruses, including highly pathogenic H5N1, from poultry in live bird markets in Hanoi, Vietnam, in 2001.

Wheat archive links long-term fungal pathogen population dynamics to air pollution.

Ventilator-associated pneumonia.

The presence of valine at residue 129 in human prion protein accelerates amyloid formation.

Influenza A (H3N2) outbreak, Nepal.

Rab9 GTPase is required for replication of human immunodeficiency virus type 1, filoviruses, and measles virus.

The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis.

Detecting hyperprolactinaemia in mental health patients.

Synthesis and characterization of ruthenacarborane complexes incorporating chelating N-donor ligands: unexpected luminescence from the complex [3-CO-3,3-kappa2-Me2N(CH2)2NMe2]-closo-3,1,2-RuC2B9H11].

A vitellogenic-like carboxypeptidase expressed by human macrophages is localized in endoplasmic reticulum and membrane ruffles.

Adoptive transfer of myelin basic protein-induced experimental autoimmune encephalomyelitis between SJL and B10.S mice: correlation of priming milieus with susceptibility and resistance phenotypes.

Fiber-optic infrared reflectance spectroelectrochemical studies of osmium and ruthenium nitrosyl porphyrins containing alkoxide and thiolate ligands.

Genetic analysis of host resistance to intracellular pathogens: lessons from studies of Toxoplasma gondii infection.

Flagellar motility is required for the viability of the bloodstream trypanosome.

Fiber-optic infrared spectroelectrochemical studies of six-coordinate manganese nitrosyl porphyrins in nonaqueous media.

Prevalence of Barrett's Esophagus.

Design of treatment trials for functional gastrointestinal disorders.

Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation.

Expert clinical rules automate steps in delivering evidence-based care in the electronic health record.

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages.

Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation.

Characterization of the epidemic influenza B viruses isolated during 2004-2005 season in Taiwan.

Diagnostic microarray for influenza B viruses.

Unrecognized GERD symptoms are associated with excessive daytime sleepiness in patients undergoing sleep studies.

Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast.

TNF-alpha suppresses alpha-smooth muscle actin expression in human dermal fibroblasts: an implication for abnormal wound healing.

Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide.

Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells.

Prevalence of hyperprolactinaemia in a naturalistic cohort of schizophrenia and bipolar outpatients during treatment with typical and atypical antipsychotics.

An essential quality control mechanism at the eukaryotic basal body prior to intraflagellar transport.

Heterologous amyloid seeding: revisiting the role of acetylcholinesterase in Alzheimer's disease.

The population genetic structure of clonal organisms generated by exponentially bounded and fat-tailed dispersal.

The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules.

High cell surface expression of CD4 allows distinction of CD4(+)CD25(+) antigen-specific effector T cells from CD4(+)CD25(+) regulatory T cells in murine experimental autoimmune encephalomyelitis.

Intracellular NOD-like receptors in innate immunity, infection and disease.

Chalcogenides as organocatalysts.

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands.

Anti-biotin antibodies offer superior organelle-specific labelling of mitochondria over avidin or streptavidin.

Structural elements regulating amyloidogenesis: a cholinesterase model system.

Isolation and characterization of a neutral imino-semiquinone radical.

The global circulation of seasonal influenza A (H3N2) viruses.

The Reflux Disease Questionnaire: a measure for assessment of treatment response in clinical trials.

Cardiovascular high-risk patients--treat to protect, but whom?

No HOPE without proof: do ARBs meet the standard for cardiovascular protection?

Cardiac and vascular protection: the potential of ONTARGET.

Targeting cardiovascular protection: the concept of dual renin-angiotensin system control.

Prospects for renovascular protection by more aggressive renin-angiotensin system control.

A new dawn in cardio and vascular protection v. cardiovascular high-risk patients: treat to protect.

Treating to protect: current cardiovascular treatment approaches and remaining needs.

Array-based goniospectroradiometer for measurement of spectral radiant intensity and spectral total flux of light sources.

A review of the association between antipsychotic use and hyperprolactinaemia.

Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3.

NOD-like receptors (NLRs): bona fide intracellular microbial sensors.

NOD-like receptors: role in innate immunity and inflammatory disease.

The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis.

Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses.

Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography.

Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei.

Comparison of precipitation chemistry measurements obtained by the Canadian Air and Precipitation Monitoring Network and National Atmospheric Deposition Program for the period 1995-2004.

Emergence of a novel swine-origin influenza A (H1N1) virus in humans.

Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides.

Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans.

Localisation of DivIVA by targeting to negatively curved membranes.

Pirfenidone is renoprotective in diabetic kidney disease.

Genetic analysis of avian influenza A viruses isolated from domestic waterfowl in live-bird markets of Hanoi, Vietnam, preceding fatal H5N1 human infections in 2004.

Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation.

Cell morphogenesis of Trypanosoma brucei requires the paralogous, differentially expressed calpain-related proteins CAP5.5 and CAP5.5V.

Competing discrete interfacial effects are critical for amyloidogenesis.

T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii.

Genomic events underlying the changes in adamantane resistance among influenza A(H3N2) viruses during 2006-2008.

Host cell selection of influenza neuraminidase variants: implications for drug resistance monitoring in A(H1N1) viruses.

Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome.

A protocol for patients with cardiovascular implantable devices undergoing magnetic resonance imaging (MRI): should defibrillation threshold testing be performed post-(MRI).

Validation of a method for preparing influenza H5N1 simulated samples.

Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans.

Characterization of deformable mirrors for spherical aberration correction in optical sectioning microscopy.

Bioanalysis of N-acetyl-aspartyl-glutamate as a marker of glutamate carboxypeptidase II inhibition.

Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection.

Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei.

Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation.

T cells that trigger acute experimental autoimmune encephalomyelitis also mediate subsequent disease relapses and predominantly produce IL-17.

Facile determination of the spectra of unstable electrode products using simultaneous fiber-optic chronoabsorptometry and chronoamperometry.

2009 H1N1 swine flu: the 2010 perspective.

Evaluating clinical decision support rules as an intervention in clinician workflows with technology.

Comprehensive assessment of 2009 pandemic influenza A (H1N1) virus drug susceptibility in vitro.

Randomized controlled trial of toothbrushing to reduce ventilator-associated pneumonia pathogens and dental plaque in a critical care unit.

The ever-expanding function of NOD2: autophagy, viral recognition, and T cell activation.

Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division.

A novel role for BRCA1 in regulating breast cancer cell spreading and motility.

Transcriptional and cellular responses to defective mitochondrial proteolysis in fission yeast.

Differential levels of resistance to disease induction and development of relapsing experimental autoimmune encephalomyelitis in two H-2b-restricted mouse strains.

The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes.

Preparing for the availability of a partially effective HIV vaccine: some lessons from other licensed vaccines.

Cutting edge: Crohn's disease-associated Nod2 mutation limits production of proinflammatory cytokines to protect the host from Enterococcus faecalis-induced lethality.

Hedgehog signaling regulates nociceptive sensitization.

Retooling manganese(III) porphyrin-based peroxynitrite decomposition catalysts for selectivity and oral activity: a potential new strategy for treating chronic pain.

Arbitrary self-assembly of peptide extracellular microscopic matrices.

Both exogenous commensal and endogenous self antigens stimulate T cell proliferation under lymphopenic conditions.

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine.

Analysis of influenza viruses from patients clinically suspected of infection with an oseltamivir resistant virus during the 2009 pandemic in the United States.

The formation and positioning of cilia in Ciona intestinalis embryos in relation to the generation and evolution of chordate left-right asymmetry.

Inhibition of influenza A virus replication by antagonism of a PI3K-AKT-mTOR pathway member identified by gene-trap insertional mutagenesis.

Heavyweight science.

Identification of cellular proteins required for replication of human immunodeficiency virus type 1.

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense.

Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes.

Three-dimensional cell morphometry for the quantification of cell-substrate interactions.

A case of internal ophthalmoplegia associated with varicella zoster.

Evolution of GOLDEN2-LIKE gene function in C(3) and C (4) plants.

Combined effects of agitation, macromolecular crowding, and interfaces on amyloidogenesis.

Ultralow-loss silicon ring resonators.

"Register and Roll": A Novel Initiative to Improve First Door-to-Balloon Time in ST Elevation Myocardial Infarction.

Polarization effects on contrast in structured illumination microscopy.

Stable ruthenium nitrosyl porphyrins with axial O-bonded ligands; preparation and redox behavior.

Synthesis and electrochemical reactivity of molybdenum dicarbonyl supported by a redox-active α-diimine ligand.

Detection and molecular characterisation of Pyrenopeziza brassicae isolates resistant to methyl benzimidazole carbamates.

Calmodulin is required for paraflagellar rod assembly and flagellum-cell body attachment in trypanosomes.

Investigation of the confocal wavefront sensor and its application to biological microscopy.

Urine catalytic iron and neutrophil gelatinase-associated lipocalin as companion early markers of acute kidney injury after cardiac surgery: a prospective pilot study.

R292K substitution and drug susceptibility of influenza A(H7N9) viruses.

Outbreak of variant influenza A(H3N2) virus in the United States.

Alterations in the predicted regulatory and coding regions of the sterol 14α-demethylase gene (CYP51) confer decreased azole sensitivity in the oilseed rape pathogen Pyrenopeziza brassicae.

Paralog re-emergence: a novel, historically contingent mechanism in the evolution of antimicrobial resistance.

Botrytis species: relentless necrotrophic thugs or endophytes gone rogue?

Lessons learned from studies of natural resistance in murine experimental autoimmune encephalomyelitis.

Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells.

Optimized approaches for optical sectioning and resolution enhancement in 2D structured illumination microscopy.

Adaptation of international guidelines for metastatic colorectal cancer: an asian consensus.

Differences in influenza seasonality by latitude, northern India.

A randomized controlled trial comparing a low-residue diet versus clear liquids for colonoscopy preparation: impact on tolerance, procedure time, and adenoma detection rate.

Thermochromic and photoresponsive cyanometalate Fe/Co squares: toward control of the electron transfer temperature.

Measurement of refractive index by nanoparticle tracking analysis reveals heterogeneity in extracellular vesicles.

Filming protein fibrillogenesis in real time.

High speed structured illumination microscopy in optically thick samples.

Investigation of an Outbreak of Variant Influenza A(H3N2) Virus Infection Associated With an Agricultural Fair-Ohio, August 2012.

Amniotic fluid LPCAT1 mRNA correlates with the lamellar body count.

Clonidine withdrawal induced sympathetic surge.

Evaluation of Salivary Transcriptome Markers for the Early Detection of Oral Squamous Cell Cancer in a Prospective Blinded Trial.

Determination of Predominance of Influenza Virus Strains in the Americas.

Evaluation of the King-Devick test as a concussion screening tool in high school football players.

The effect of succinate dehydrogenase inhibitor/azole mixtures on selection of Zymoseptoria tritici isolates with reduced sensitivity.

Transient Microgeographic Clines during B Chromosome Invasion.