Laboratory of Neuromodulation,
Department of Physical Medicine & Rehabilitation,
Laboratory of Neuromodulation, Department of Physical Medicine & Rehabilitation
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Differential regulation of E2F1, DP1, and the E2F1/DP1 complex by ARF.
Molecular and cellular biology Dec, 2002 | Pubmed ID: 12446760
P19ARF inhibits the functions of the HPV16 E7 oncoprotein.
Oncogene Aug, 2003 | Pubmed ID: 12934109
Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor.
Genes & development Apr, 2004 | Pubmed ID: 15082532
Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc.
The Journal of biological chemistry Aug, 2004 | Pubmed ID: 15199070
ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF.
Molecular and cellular biology Sep, 2005 | Pubmed ID: 16135794
XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America May, 2006 | Pubmed ID: 16670198
Regulation of activation induced deaminase via phosphorylation.
Advances in experimental medicine and biology , 2007 | Pubmed ID: 17338181
Evolution of the immunoglobulin heavy chain class switch recombination mechanism.
Advances in immunology , 2007 | Pubmed ID: 17560275
In vitro modulation of endogenous rhythms by AC electric fields: Syncing with clinical brain stimulation.
The Journal of physiology Oct, 2007 | Pubmed ID: 17702811
Rational modulation of neuronal processing with applied electric fields.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2006 | Pubmed ID: 17946911
Transcranial current stimulation focality using disc and ring electrode configurations: FEM analysis.
Journal of neural engineering Jun, 2008 | Pubmed ID: 18441418
Transcranial direct current stimulation for major depression: a general system for quantifying transcranial electrotherapy dosage.
Current treatment options in neurology Sep, 2008 | Pubmed ID: 18782510
Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching.
The Journal of experimental medicine Dec, 2008 | Pubmed ID: 19064702
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2009 | Pubmed ID: 19196992
Establishing safety limits for transcranial direct current stimulation.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Jun, 2009 | Pubmed ID: 19394269
Bio-heat transfer model of transcranial DC stimulation: comparison of conventional pad versus ring electrode.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2009 | Pubmed ID: 19964238
One-dimensional representation of a neuron in a uniform electric field.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2009 | Pubmed ID: 19964438
Transcranial direct current stimulation in patients with skull defects and skull plates: high-resolution computational FEM study of factors altering cortical current flow.
NeuroImage Oct, 2010 | Pubmed ID: 20435146
Electrodes for high-definition transcutaneous DC stimulation for applications in drug delivery and electrotherapy, including tDCS.
Journal of neuroscience methods Jul, 2010 | Pubmed ID: 20488204
Gyri-precise head model of transcranial direct current stimulation: improved spatial focality using a ring electrode versus conventional rectangular pad.
Brain stimulation Oct, 2009 | Pubmed ID: 20648973
Electrode montages for tDCS and weak transcranial electrical stimulation: role of "return" electrode's position and size.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Dec, 2010 | Pubmed ID: 21035740
Cutaneous perception during tDCS: role of electrode shape and sponge salinity.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Apr, 2011 | Pubmed ID: 21075048
Transcranial DC stimulation in fibromyalgia: optimized cortical target supported by high-resolution computational models.
The journal of pain : official journal of the American Pain Society May, 2011 | Pubmed ID: 21497140
Optimized multi-electrode stimulation increases focality and intensity at target.
Journal of neural engineering Aug, 2011 | Pubmed ID: 21659696
Individualized model predicts brain current flow during transcranial direct-current stimulation treatment in responsive stroke patient.
Brain stimulation Jul, 2011 | Pubmed ID: 21777878
Guidelines for precise and accurate computational models of tDCS.
Brain stimulation Jul, 2011 | Pubmed ID: 21782547
A Pilot Study of the Tolerability and Effects of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Pain Perception.
The journal of pain : official journal of the American Pain Society Feb, 2012 | Pubmed ID: 22104190
Left lateralizing transcranial direct current stimulation improves reading efficiency.
Brain stimulation May, 2011 | Pubmed ID: 22305346
tDCS-induced analgesia and electrical fields in pain-related neural networks in chronic migraine.
Headache Sep, 2012 | Pubmed ID: 22512348
Temperature control at DBS electrodes using a heat sink: experimentally validated FEM model of DBS lead architecture.
Journal of neural engineering Aug, 2012 | Pubmed ID: 22764359
High-resolution modeling assisted design of customized and individualized transcranial direct current stimulation protocols.
Neuromodulation : journal of the International Neuromodulation Society Jul, 2012 | Pubmed ID: 22780230
Transcranial direct current stimulation accelerates allocentric target detection.
Brain stimulation May, 2013 | Pubmed ID: 22784444
Computational models of transcranial direct current stimulation.
Clinical EEG and neuroscience : official journal of the EEG and Clinical Neuroscience Society (ENCS) Jul, 2012 | Pubmed ID: 22956646
Cranial electrotherapy stimulation and transcranial pulsed current stimulation: a computer based high-resolution modeling study.
NeuroImage Jan, 2013 | Pubmed ID: 23041337
Inter-Individual Variation during Transcranial Direct Current Stimulation and Normalization of Dose Using MRI-Derived Computational Models.
Frontiers in psychiatry / Frontiers Research Foundation , 2012 | Pubmed ID: 23097644
Imaging artifacts induced by electrical stimulation during conventional fMRI of the brain.
NeuroImage Oct, 2012 | Pubmed ID: 23099102
Comparing Cortical Plasticity Induced by Conventional and High-Definition 4 × 1 Ring tDCS: A Neurophysiological Study.
Brain stimulation Jul, 2013 | Pubmed ID: 23149292
A pilot study on effects of 4×1 High-Definition tDCS on motor cortex excitability.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2012 | Pubmed ID: 23365997
An automated method for high-definition transcranial direct current stimulation modeling.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2012 | Pubmed ID: 23367144
On the role of electric field orientation in optimal design of transcranial current stimulation.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2012 | Pubmed ID: 23367400
Physiological and modeling evidence for focal transcranial electrical brain stimulation in humans: a basis for high-definition tDCS.
NeuroImage Jul, 2013 | Pubmed ID: 23370061
Focal modulation of the primary motor cortex in fibromyalgia using 4×1-ring high-definition transcranial direct current stimulation (HD-tDCS): immediate and delayed analgesic effects of cathodal and anodal stimulation.
The journal of pain : official journal of the American Pain Society Apr, 2013 | Pubmed ID: 23415877
Transcranial electrical stimulation accelerates human sleep homeostasis.
PLoS computational biology , 2013 | Pubmed ID: 23459152
Targeted transcranial direct current stimulation for rehabilitation after stroke.
NeuroImage Jul, 2013 | Pubmed ID: 23473936
Cellular effects of acute direct current stimulation: somatic and synaptic terminal effects.
The Journal of physiology May, 2013 | Pubmed ID: 23478132
Validation of finite element model of transcranial electrical stimulation using scalp potentials: implications for clinical dose.
Journal of neural engineering Jun, 2013 | Pubmed ID: 23649036
Noninvasive transcranial direct current stimulation over the left prefrontal cortex facilitates cognitive flexibility in tool use.
Cognitive neuroscience Jun, 2013 | Pubmed ID: 23894253
Automated MRI segmentation for individualized modeling of current flow in the human head.
Journal of neural engineering Dec, 2013 | Pubmed ID: 24099977
Clinician accessible tools for GUI computational models of transcranial electrical stimulation: BONSAI and SPHERES.
Brain stimulation Jul-Aug, 2014 | Pubmed ID: 24776786
Feasibility of using high-definition transcranial direct current stimulation (HD-tDCS) to enhance treatment outcomes in persons with aphasia.
NeuroRehabilitation , 2015 | Pubmed ID: 25547776
Remotely-supervised transcranial direct current stimulation (tDCS) for clinical trials: guidelines for technology and protocols.
Frontiers in systems neuroscience , 2015 | Pubmed ID: 25852494
On the Use of the Terms Anodal and Cathodal in High-Definition Transcranial Direct Current Stimulation: A Technical Note.
Neuromodulation : journal of the International Neuromodulation Society Jun, 2015 | Pubmed ID: 26076228
State-of-art neuroanatomical target analysis of high-definition and conventional tDCS montages used for migraine and pain control.
Frontiers in neuroanatomy , 2015 | Pubmed ID: 26236199
A Feasibility Study of Bilateral Anodal Stimulation of the Prefrontal Cortex Using High-Definition Electrodes in Healthy Participants.
The Yale journal of biology and medicine Sep, 2015 | Pubmed ID: 26339204
Clinically Effective Treatment of Fibromyalgia Pain With High-Definition Transcranial Direct Current Stimulation: Phase II Open-Label Dose Optimization.
The journal of pain : official journal of the American Pain Society Oct, 2015 | Pubmed ID: 26456677
Anti-CD25 monoclonal antibody Fc variants differentially impact regulatory T cells and immune homeostasis.
Immunology Jul, 2016 | Pubmed ID: 27012310
Transcranial Direct Current Stimulation Is Feasible for Remotely Supervised Home Delivery in Multiple Sclerosis.
Neuromodulation : journal of the International Neuromodulation Society Dec, 2016 | Pubmed ID: 27089545
Remotely Supervised Transcranial Direct Current Stimulation Increases the Benefit of At-Home Cognitive Training in Multiple Sclerosis.
Neuromodulation : journal of the International Neuromodulation Society Feb, 2017 | Pubmed ID: 28225155
On comparing in vivo intracranial recordings in non-human primates to predictions of optimized transcranial electrical stimulation.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference Aug, 2016 | Pubmed ID: 28268671
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis.
Science translational medicine Mar, 2017 | Pubmed ID: 28356511
Remotely supervised transcranial direct current stimulation for the treatment of fatigue in multiple sclerosis: Results from a randomized, sham-controlled trial.
Multiple sclerosis (Houndmills, Basingstoke, England) Sep, 2017 | Pubmed ID: 28937310
Transcranial Direct Current Stimulation Facilitates Associative Learning and Alters Functional Connectivity in the Primate Brain.
Current biology : CB Oct, 2017 | Pubmed ID: 29033331
Limited output transcranial electrical stimulation (LOTES-2017): Engineering principles, regulatory statutes, and industry standards for wellness, over-the-counter, or prescription devices with low risk.
Brain stimulation Jan - Feb, 2018 | Pubmed ID: 29122535
Automatic M1-SO Montage Headgear for Transcranial Direct Current Stimulation (TDCS) Suitable for Home and High-Throughput In-Clinic Applications.
Neuromodulation : journal of the International Neuromodulation Society May, 2018 | Pubmed ID: 29762886
Generalizing remotely supervised transcranial direct current stimulation (tDCS): feasibility and benefit in Parkinson's disease.
Journal of neuroengineering and rehabilitation 12, 2018 | Pubmed ID: 30522497
Prefronto-cerebellar neuromodulation affects appetite in obesity.
International journal of obesity (2005) 10, 2019 | Pubmed ID: 30538282
Long term at-home treatment with transcranial direct current stimulation (tDCS) improves symptoms of cerebellar ataxia: a case report.
Journal of neuroengineering and rehabilitation 03, 2019 | Pubmed ID: 30890162
Realistic volumetric-approach to simulate transcranial electric stimulation-ROAST-a fully automated open-source pipeline.
Journal of neural engineering 07, 2019 | Pubmed ID: 31071686
Cortico-spinal tDCS in ALS: A randomized, double-blind, sham-controlled trial.
Brain stimulation Sep - Oct, 2019 | Pubmed ID: 31204206
Transcranial electrical stimulation nomenclature.
Brain stimulation Jul, 2019 | Pubmed ID: 31358456
Safety Aspects, Tolerability and Modeling of Retinofugal Alternating Current Stimulation.
Frontiers in neuroscience , 2019 | Pubmed ID: 31440126
Remotely supervised transcranial direct current stimulation: A feasibility study for amyotrophic lateral sclerosis.
NeuroRehabilitation , 2019 | Pubmed ID: 31796701
Methodology for tDCS integration with fMRI.
Human brain mapping Dec, 2019 | Pubmed ID: 31872943
A Multimodal Stimulation Cell Culture Bioreactor for Tissue Engineering: A Numerical Modelling Approach.
Polymers Apr, 2020 | Pubmed ID: 32325660
Optimization of interferential stimulation of the human brain with electrode arrays.
Journal of neural engineering 06, 2020 | Pubmed ID: 32403096
Optimized Electrode Placements for Non-invasive Electrical Stimulation of the Olfactory Bulb and Olfactory Mucosa.
Frontiers in neuroscience , 2020 | Pubmed ID: 33262684
A double-blind sham-controlled phase 1 clinical trial of tDCS of the dorsolateral prefrontal cortex in cocaine inpatients: Craving, sleepiness, and contemplation to change.
The European journal of neuroscience 05, 2021 | Pubmed ID: 33662163
Exposure to gamma tACS in Alzheimer's disease: A randomized, double-blind, sham-controlled, crossover, pilot study.
Brain stimulation May-Jun, 2021 | Pubmed ID: 33762220
Motor and cognitive outcomes of cerebello-spinal stimulation in neurodegenerative ataxia.
Brain : a journal of neurology 09, 2021 | Pubmed ID: 33950222
A Systematic Review and Meta-Analysis on the Efficacy of Repeated Transcranial Direct Current Stimulation for Migraine.
Journal of pain research , 2021 | Pubmed ID: 33953607
High-resolution computational modeling of the current flow in the outer ear during transcutaneous auricular Vagus Nerve Stimulation (taVNS).
Brain stimulation Nov-Dec, 2021 | Pubmed ID: 34517143
Dataset of concurrent EEG, ECG, and behavior with multiple doses of transcranial electrical stimulation.
Scientific data 10, 2021 | Pubmed ID: 34707095
A checklist for assessing the methodological quality of concurrent tES-fMRI studies (ContES checklist): a consensus study and statement.
Nature protocols 03, 2022 | Pubmed ID: 35121855
Comparison of Transcranial Focused Ultrasound and Transcranial Pulse Stimulation for Neuromodulation: A Computational Study.
Neuromodulation : journal of the International Neuromodulation Society Jun, 2022 | Pubmed ID: 35125300
Determination of Current Flow Induced by Transcutaneous Electrical Nerve Stimulation for the Treatment of Migraine: Potential for Optimization.
Frontiers in pain research (Lausanne, Switzerland) , 2021 | Pubmed ID: 35295421
Case Report: Initial Evidence of Safety and Efficacy of High Definition-Transcranial Direct Current Stimulation in a Patient With Neuropathic Pain and Implanted Spinal Cord Stimulator.
Frontiers in pain research (Lausanne, Switzerland) , 2021 | Pubmed ID: 35295503
The Concept, Development, and Application of a Home-Based High-Definition tDCS for Bilateral Motor Cortex Modulation in Migraine and Pain.
Frontiers in pain research (Lausanne, Switzerland) , 2022 | Pubmed ID: 35295794
Tolerability and feasibility of at-home remotely supervised transcranial direct current stimulation (RS-tDCS): Single-center evidence from 6,779 sessions.
Brain stimulation May-Jun, 2022 | Pubmed ID: 35470019
Increasing Brain Gamma Activity Improves Episodic Memory and Restores Cholinergic Dysfunction in Alzheimer's Disease.
Annals of neurology 08, 2022 | Pubmed ID: 35607946
Dose-Response Transcranial Electrical Stimulation Study Design: A Well-Controlled Adaptive Seamless Bayesian Method to Illuminate Negative Valence Role in Tinnitus Perception.
Frontiers in human neuroscience , 2022 | Pubmed ID: 35677206
Efficacy of Galvanic Vestibular Stimulation as a Display Modality Dissociated from Self-Orientation.
Human factors Aug, 2022 | Pubmed ID: 35971664
Digitalized transcranial electrical stimulation: A consensus statement.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Nov, 2022 | Pubmed ID: 36115809
Cerebral metabolic rate of oxygen (CMRO) changes measured with simultaneous tDCS-MRI in healthy adults.
Brain research Dec, 2022 | Pubmed ID: 36150457
Non-invasive brain stimulation for fatigue in post-acute sequelae of SARS-CoV-2 (PASC).
Brain stimulation , 2023 | Pubmed ID: 36693536
A Scalable Framework for Closed-Loop Neuromodulation with Deep Learning.
bioRxiv : the preprint server for biology Jan, 2023 | Pubmed ID: 36712027
Impact of galvanic vestibular stimulation electrode current density on brain current flow patterns: Does electrode size matter?
PloS one , 2023 | Pubmed ID: 36735686
Limited output transcranial electrical stimulation 2023 (LOTES-2023): Updates on engineering principles, regulatory statutes, and industry standards for wellness, over-the-counter, or prescription devices with low risk.
Brain stimulation , 2023 | Pubmed ID: 37201865
Remotely supervised at-home tDCS for veterans with persistent post-traumatic headache: a double-blind, sham-controlled randomized pilot clinical trial.
Frontiers in neurology , 2023 | Pubmed ID: 37213913
Impact of modeled field of view in electroconvulsive therapy current flow simulations.
Frontiers in psychiatry , 2023 | Pubmed ID: 37275969
Contact dermatitis following an intensive transcranial direct current stimulation protocol for major depressive disorder.
Brain stimulation , 2023 | Pubmed ID: 37619893
Home-administered transcranial direct current stimulation is a feasible intervention for depression: an observational cohort study.
Frontiers in psychiatry , 2023 | Pubmed ID: 37674552
Remotely supervised at-home delivery of taVNS for autism spectrum disorder: feasibility and initial efficacy.
Frontiers in psychiatry , 2023 | Pubmed ID: 37840787
Optimized high-definition tDCS in patients with skull defects and skull plates.
Frontiers in human neuroscience , 2023 | Pubmed ID: 37929226
Cortico-spinal tDCS in amyotrophic lateral sclerosis: A randomized, double-blind, sham-controlled trial followed by an open-label phase.
Brain stimulation , 2023 | Pubmed ID: 37977335
Effect of non-invasive spinal cord stimulation in unmedicated adults with major depressive disorder: a pilot randomized controlled trial and induced current flow pattern.
Molecular psychiatry Dec, 2023 | Pubmed ID: 38123726
Amplitude-determined seizure-threshold, electric field modeling, and electroconvulsive therapy antidepressant and cognitive outcomes.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Mar, 2024 | Pubmed ID: 38212442
Mauricio F. Villamar1,2,
Magdalena Sarah Volz1,3,
Marom Bikson4,
Abhishek Datta1,4,
Alexandre F. DaSilva*,5,
Felipe Fregni*,1
1Laboratory of Neuromodulation, Department of Physical Medicine & Rehabilitation, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School,
2School of Medicine, Pontifical Catholic University of Ecuador,
3, Charité University Medicine Berlin,
4, The City College of The City University of New York,
5Headache & Orofacial Pain Effort (H.O.P.E.), Biologic & Materials Sciences, School of Dentistry, University of Michigan
Ingrid Rebello-Sanchez1,
Joao Parente1,
Kevin Pacheco-Barrios1,2,
Anna Marduy1,
Danielle Carolina Pimenta1,
Daniel Lima1,
Eric Slawka1,
Alejandra Cardenas-Rojas1,
Gleysson Rodrigues Rosa1,
Kamran Nazim3,
Abhishek Datta3,4,
Felipe Fregni1
1Neuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School,
2, Universidad de Investigación para la Generación y Síntesis de Evidencia en Salud, Universidad San Ignacio de Loyola,
3Research and Development, Soterix Medical,
4, City College of New York
Kevin Pacheco-Barrios*,1,2,
Daniela Martinez-Magallanes*,1,
Cristina Xicota Naqui1,3,
Marianna Daibes1,
Elly Pichardo1,
Alejandra Cardenas-Rojas1,
David Crandell4,
Anahita Dua5,
Abhishek Datta6,7,
Wolnei Caumo8,9,10,
Felipe Fregni1
1Neuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital, Massachusetts General Hospital, Harvard Medical School,
2Vicerrectorado de Investigación, Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola,
3Nursing Department, Universitat Internacional de Catalunya,
4Spaulding Rehabilitation Hospital, Harvard Medical School,
5Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Harvard Medical School,
6Research and Development, Soterix Medical,
7, City College of New York,
8Post-Graduate Program in Medical Sciences, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS),
9Laboratory of Pain & Neuromodulation, Hospital de Clinicas de Porto Alegre (HCPA),
10Pain and Palliative Care Service, Hospital de Clinicas de Porto Alegre (HCPA)