Jordan D. Miller

Cardiorespiratory effects of inelastic chest wall restriction.

Biventricular adaptation to volume overload in mice with aortic regurgitation.

MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure.

Evidence for active regulation of pro-osteogenic signaling in advanced aortic valve disease.

Calcific aortic valve stenosis: methods, models, and mechanisms.

Vascular function during prolonged progression and regression of atherosclerosis in mice.

TGF-β signalling and reactive oxygen species drive fibrosis and matrix remodelling in myxomatous mitral valves.

Fibrocalcific aortic valve disease: opportunity to understand disease mechanisms using mouse models.

Transcriptional and phenotypic changes in aorta and aortic valve with aging and MnSOD deficiency in mice.

Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.

Impact of aortic valve calcification, as measured by MDCT, on survival in patients with aortic stenosis: results of an international registry study.

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

Reward and Toxicity of Cocaine Metabolites Generated by Cocaine Hydrolase.

Nonbiased Molecular Screening Identifies Novel Molecular Regulators of Fibrogenic and Proliferative Signaling in Myxomatous Mitral Valve Disease.

Molecular Determinants of Calpain-dependent Cleavage of Junctophilin-2 Protein in Cardiomyocytes.

Sex-related differences in calcific aortic stenosis: correlating clinical and echocardiographic characteristics and computed tomography aortic valve calcium score to excised aortic valve weight.

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.

Arterial calcification: Conscripted by collagen.

Bidirectional Translation in Cardiovascular Calcification.

Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.

Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease.

Left ventricular dysfunction after degenerative mitral valve repair: A question of better molecular targets or better surgical timing?

Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes.

Cellular senescence: Implications for metabolic disease.

High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver.

The Impact of Frailty on Patient-Centered Outcomes Following Aortic Valve Replacement.

Sirt6 deficiency results in progression of glomerular injury in the kidney.

Pathophysiology of Aortic Valve Stenosis: Is It Both Fibrocalcific and Sex Specific?

TRPC6 and TRPC4 Heteromultimerization Mediates Store Depletion-Activated NCX1 Reversal in Proliferative Vascular Smooth Muscle Cells.

Ca Entry Through Reverse Mode Na/Ca Exchanger Contributes to Store Operated Channel-Mediated Neointima Formation After Arterial Injury.

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD Decline.

Senolytics improve physical function and increase lifespan in old age.

Sirt6 deficiency impairs corneal epithelial wound healing.

Smooth muscle brain-derived neurotrophic factor contributes to airway hyperreactivity in a mouse model of allergic asthma.

Network Tomography for Understanding Phenotypic Presentations in Aortic Stenosis.

Length-independent telomere damage drives post-mitotic cardiomyocyte senescence.

Targeting senescent cells alleviates obesity-induced metabolic dysfunction.

Late-life time-restricted feeding and exercise differentially alter healthspan in obesity.

Influences of Sex and Estrogen in Arterial and Valvular Calcification.

The Use of Virtual Reality to Reduce Preoperative Anxiety in First-Time Sternotomy Patients: A Randomized Controlled Pilot Trial.

Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span.

MnSOD protects against vascular calcification independent of changes in vascular function in hypercholesterolemic mice.

Effects of Altering Mitochondrial Antioxidant Capacity on Molecular and Phenotypic Drivers of Fibrocalcific Aortic Valve Stenosis.