Department of Surgery,
Department of Physiology & Biomedical Engineering,
Physiology & Biomedical Engineering,
Surgery
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Cardiorespiratory effects of inelastic chest wall restriction.
Journal of applied physiology (Bethesda, Md. : 1985) Jun, 2002 | Pubmed ID: 12015356
Biventricular adaptation to volume overload in mice with aortic regurgitation.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance , 2009 | Pubmed ID: 19671155
MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure.
American journal of physiology. Heart and circulatory physiology May, 2010 | Pubmed ID: 20304815
Evidence for active regulation of pro-osteogenic signaling in advanced aortic valve disease.
Arteriosclerosis, thrombosis, and vascular biology Dec, 2010 | Pubmed ID: 20864669
Calcific aortic valve stenosis: methods, models, and mechanisms.
Circulation research May, 2011 | Pubmed ID: 21617136
Vascular function during prolonged progression and regression of atherosclerosis in mice.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2013 | Pubmed ID: 23307875
TGF-β signalling and reactive oxygen species drive fibrosis and matrix remodelling in myxomatous mitral valves.
Cardiovascular research Jul, 2013 | Pubmed ID: 23554457
Fibrocalcific aortic valve disease: opportunity to understand disease mechanisms using mouse models.
Circulation research Jul, 2013 | Pubmed ID: 23833295
Transcriptional and phenotypic changes in aorta and aortic valve with aging and MnSOD deficiency in mice.
American journal of physiology. Heart and circulatory physiology Nov, 2013 | Pubmed ID: 23997094
Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.
Circulation Apr, 2014 | Pubmed ID: 24519927
Impact of aortic valve calcification, as measured by MDCT, on survival in patients with aortic stenosis: results of an international registry study.
Journal of the American College of Cardiology Sep, 2014 | Pubmed ID: 25236511
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Aging cell Aug, 2015 | Pubmed ID: 25754370
Reward and Toxicity of Cocaine Metabolites Generated by Cocaine Hydrolase.
Cellular and molecular neurobiology Aug, 2015 | Pubmed ID: 25814464
Nonbiased Molecular Screening Identifies Novel Molecular Regulators of Fibrogenic and Proliferative Signaling in Myxomatous Mitral Valve Disease.
Circulation. Cardiovascular genetics Jun, 2015 | Pubmed ID: 25814644
Molecular Determinants of Calpain-dependent Cleavage of Junctophilin-2 Protein in Cardiomyocytes.
The Journal of biological chemistry Jul, 2015 | Pubmed ID: 26063807
Sex-related differences in calcific aortic stenosis: correlating clinical and echocardiographic characteristics and computed tomography aortic valve calcium score to excised aortic valve weight.
European heart journal Feb, 2016 | Pubmed ID: 26508159
17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.
The journals of gerontology. Series A, Biological sciences and medical sciences Jan, 2017 | Pubmed ID: 26809497
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Nature Feb, 2016 | Pubmed ID: 26840489
Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.
Aging cell Oct, 2016 | Pubmed ID: 26864908
Arterial calcification: Conscripted by collagen.
Nature materials Mar, 2016 | Pubmed ID: 26906958
Bidirectional Translation in Cardiovascular Calcification.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2016 | Pubmed ID: 26912744
Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.
Diabetes Jun, 2016 | Pubmed ID: 26983960
Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease.
Cell metabolism Jun, 2016 | Pubmed ID: 27304512
Left ventricular dysfunction after degenerative mitral valve repair: A question of better molecular targets or better surgical timing?
The Journal of thoracic and cardiovascular surgery Oct, 2016 | Pubmed ID: 27523402
Frameworks for Proof-of-Concept Clinical Trials of Interventions That Target Fundamental Aging Processes.
The journals of gerontology. Series A, Biological sciences and medical sciences Nov, 2016 | Pubmed ID: 27535966
Cellular senescence: Implications for metabolic disease.
Molecular and cellular endocrinology Aug, 2016 | Pubmed ID: 27591120
High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver.
Epigenetics Jan, 2017 | Pubmed ID: 27858497
The Impact of Frailty on Patient-Centered Outcomes Following Aortic Valve Replacement.
The journals of gerontology. Series A, Biological sciences and medical sciences Jul, 2017 | Pubmed ID: 28329140
Sirt6 deficiency results in progression of glomerular injury in the kidney.
Aging 03, 2017 | Pubmed ID: 28351995
Pathophysiology of Aortic Valve Stenosis: Is It Both Fibrocalcific and Sex Specific?
Physiology (Bethesda, Md.) 05, 2017 | Pubmed ID: 28404735
TRPC6 and TRPC4 Heteromultimerization Mediates Store Depletion-Activated NCX1 Reversal in Proliferative Vascular Smooth Muscle Cells.
Channels (Austin, Tex.) 01, 2018 | Pubmed ID: 29560783
Ca Entry Through Reverse Mode Na/Ca Exchanger Contributes to Store Operated Channel-Mediated Neointima Formation After Arterial Injury.
The Canadian journal of cardiology 06, 2018 | Pubmed ID: 29705161
A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD Decline.
Cell metabolism May, 2018 | Pubmed ID: 29719225
Senolytics improve physical function and increase lifespan in old age.
Nature medicine 08, 2018 | Pubmed ID: 29988130
Sirt6 deficiency impairs corneal epithelial wound healing.
Aging Aug, 2018 | Pubmed ID: 30070973
Smooth muscle brain-derived neurotrophic factor contributes to airway hyperreactivity in a mouse model of allergic asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 02, 2019 | Pubmed ID: 30351991
Network Tomography for Understanding Phenotypic Presentations in Aortic Stenosis.
JACC. Cardiovascular imaging 02, 2019 | Pubmed ID: 30732719
Length-independent telomere damage drives post-mitotic cardiomyocyte senescence.
The EMBO journal 03, 2019 | Pubmed ID: 30737259
Targeting senescent cells alleviates obesity-induced metabolic dysfunction.
Aging cell 06, 2019 | Pubmed ID: 30907060
Late-life time-restricted feeding and exercise differentially alter healthspan in obesity.
Aging cell 08, 2019 | Pubmed ID: 31111669
Influences of Sex and Estrogen in Arterial and Valvular Calcification.
Frontiers in endocrinology , 2019 | Pubmed ID: 31620082
The Use of Virtual Reality to Reduce Preoperative Anxiety in First-Time Sternotomy Patients: A Randomized Controlled Pilot Trial.
Mayo Clinic proceedings 06, 2020 | Pubmed ID: 32498771
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span.
Annual review of pharmacology and toxicology 01, 2021 | Pubmed ID: 32997601
MnSOD protects against vascular calcification independent of changes in vascular function in hypercholesterolemic mice.
Atherosclerosis Jun, 2021 | Pubmed ID: 34147244
Effects of Altering Mitochondrial Antioxidant Capacity on Molecular and Phenotypic Drivers of Fibrocalcific Aortic Valve Stenosis.
Frontiers in cardiovascular medicine , 2021 | Pubmed ID: 34250048
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