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Division of Gastroenterology,
Hepatology and Nutrition,
Division of Gastroenterology, Hepatology and Nutrition
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Expression of cyclooxygenase-2 and pro-inflammatory cytokines induced by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) in human mast cells requires NF-kappa B activation.
Biological & pharmaceutical bulletin Sep, 2002 | Pubmed ID: 12230110
Tryptase precursors are preferentially and spontaneously released, whereas mature tryptase is retained by HMC-1 cells, Mono-Mac-6 cells, and human skin-derived mast cells.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2003 | Pubmed ID: 12759448
Degranulation and cytokine expression in human cord blood-derived mast cells cultured in serum-free medium with recombinant human stem cell factor.
Molecules and cells Oct, 2003 | Pubmed ID: 14651255
Recombinant human (rh) stem cell factor and rhIL-4 stimulate differentiation and proliferation of CD3+ cells from umbilical cord blood and CD3+ cells enhance FcepsilonR1 expression on fetal liver-derived mast cells in the presence of rhIL-4.
Cellular immunology Nov, 2003 | Pubmed ID: 14746805
Expression of alpha-tryptase and beta-tryptase by human basophils.
The Journal of allergy and clinical immunology Jun, 2004 | Pubmed ID: 15208589
Effect of sex and haplotype on plasma tryptase levels in healthy adults.
The Journal of allergy and clinical immunology Jul, 2004 | Pubmed ID: 15241343
Surface CD88 functionally distinguishes the MCTC from the MCT type of human lung mast cell.
The Journal of allergy and clinical immunology Jun, 2005 | Pubmed ID: 15940129
Potential of proteomics towards the investigation of the IGF-independent actions of IGFBP-3.
Expert review of proteomics Jan, 2005 | Pubmed ID: 15966854
The plasma lipidomic signature of nonalcoholic steatohepatitis.
Hepatology (Baltimore, Md.) Dec, 2009 | Pubmed ID: 19937697
Promiscuous processing of human alphabeta-protryptases by cathepsins L, B, and C.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2011 | Pubmed ID: 21562164
Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease.
Cell metabolism May, 2012 | Pubmed ID: 22560219
5-cholesten-3β,25-diol 3-sulfate decreases lipid accumulation in diet-induced nonalcoholic fatty liver disease mouse model.
Molecular pharmacology Mar, 2013 | Pubmed ID: 23258548
Metabolic profiling reveals that PNPLA3 induces widespread effects on metabolism beyond triacylglycerol remodeling in Huh-7 hepatoma cells.
American journal of physiology. Gastrointestinal and liver physiology Jul, 2014 | Pubmed ID: 24763554
Identification of novel regulatory cholesterol metabolite, 5-cholesten, 3β,25-diol, disulfate.
PloS one , 2014 | Pubmed ID: 25072708
A simple, sensitive and safe method to determine the human α/β-tryptase genotype.
PloS one , 2014 | Pubmed ID: 25545679
Activation of the GP130-STAT3 axis and its potential implications in nonalcoholic fatty liver disease.
American journal of physiology. Gastrointestinal and liver physiology May, 2015 | Pubmed ID: 25747354
Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease.
PloS one , 2015 | Pubmed ID: 26322888
Alcohol produces distinct hepatic lipidome and eicosanoid signature in lean and obese.
Journal of lipid research Jun, 2016 | Pubmed ID: 27020313
A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer.
Journal of hepatology May, 2016 | Pubmed ID: 27261415
Virginia Commonwealth University
Mulugeta Seneshaw1,
Faridoddin Mirshahi1,
Hae-Ki Min1,
Amon Asgharpour1,
Shervin Mirshahi1,
Kalyani Daita1,
Sherry Boyett1,
Prasanna K. Santhekadur2,
Michael Fuchs1,
Arun J. Sanyal1
1Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University,
2McGuire Veterans Affairs Medical Center, Research BC-101
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