Christopher M. Norris

Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models.

The Ca(V) 1.2 Ca(2+) channel is expressed in sarcolemma of type I and IIa myofibers of adult skeletal muscle.

Hippocampal 'zipper' slice studies reveal a necessary role for calcineurin in the increased activity of L-type Ca(2+) channels with aging.

Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity.

Recovery of afferent function and synaptic strength in hippocampal CA1 following traumatic brain injury.

Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.

Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures.

NFATs and Alzheimer's Disease.

Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture.

Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.

Reduction in neuronal L-type calcium channel activity in a double knock-in mouse model of Alzheimer's disease.