Pesquisa
Educação
Soluções
Entrar
PT
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
TR - Turkish
JA - Japanese
Department of Molecular and Biomedical Pharmacology,
Sanders-Brown Center on Aging
Christopher M. Norris has not added Biography.
If you are Christopher M. Norris and would like to personalize this page please email our Author Liaison for assistance.
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2005 | Pubmed ID: 15872113
The Ca(V) 1.2 Ca(2+) channel is expressed in sarcolemma of type I and IIa myofibers of adult skeletal muscle.
Muscle & nerve Oct, 2007 | Pubmed ID: 17636479
Hippocampal 'zipper' slice studies reveal a necessary role for calcineurin in the increased activity of L-type Ca(2+) channels with aging.
Neurobiology of aging Feb, 2010 | Pubmed ID: 18471936
Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity.
The Journal of biological chemistry Aug, 2008 | Pubmed ID: 18541537
Recovery of afferent function and synaptic strength in hippocampal CA1 following traumatic brain injury.
Journal of neurotrauma Dec, 2009 | Pubmed ID: 19604098
Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2009 | Pubmed ID: 19828810
Disparate effects of serum on basal and evoked NFAT activity in primary astrocyte cultures.
Neuroscience letters Jan, 2010 | Pubmed ID: 20026181
NFATs and Alzheimer's Disease.
Molecular and cellular pharmacology Jan, 2010 | Pubmed ID: 20401186
Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture.
Aging cell Feb, 2011 | Pubmed ID: 20969723
Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2011 | Pubmed ID: 21289178
Reduction in neuronal L-type calcium channel activity in a double knock-in mouse model of Alzheimer's disease.
Biochimica et biophysica acta Jan, 2012 | Pubmed ID: 22265986
University of Kentucky College of Medicine
Diana M. Mathis1,
Jennifer L. Furman2,
Christopher M. Norris2,3
1Graduate Center for Gerontology, University of Kentucky College of Public Health,
2Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine,
3Sanders-Brown Center on Aging, University of Kentucky College of Medicine
Privacidade
Termos de uso
Políticas
Entre em contato
recomende à biblioteca
Newsletter
JoVE Journal
Coleções de métodos
JoVE Encyclopedia of Experiments
Arquivo
JoVE Core
JoVE Business
JoVE Science Education
JoVE Lab Manual
Centro de Recursos para Docentes
Autores
Bibliotecários
Acesso
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados