Sally Temple

Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts.

LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal.

Creating asymmetric cell divisions by skewing endocytosis.

Embryonic stem cell self-renewal, analyzed.

Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis.

Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells.

Asymmetric distribution of EGFR receptor during mitosis generates diverse CNS progenitor cells.

Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.

Automated cell lineage construction: a rapid method to analyze clonal development established with murine neural progenitor cells.

LeX is expressed by principle progenitor cells in the embryonic nervous system, is secreted into their environment and binds Wnt-1.

PEDF: bridging neurovascular interactions in the stem cell niche.

The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells.

Making human neurons from stem cells after spinal cord injury.

Human retinal pigment epithelium cell changes and expression of alphaB-crystallin: a biomarker for retinal pigment epithelium cell change in age-related macular degeneration.

High-throughput screening of gene function in stem cells using clonal microarrays.

Taking neural crest stem cells to new heights.

Multipotent embryonic spinal cord stem cells expanded by endothelial factors and Shh/RA promote functional recovery after spinal cord injury.

shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development.

Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions.

Cell lineage tree models of neurogenesis.

The incredible elastic brain: how neural stem cells expand our minds.

Identifying the perpetrator in medulloblastoma: Dorian Gray versus Benjamin Button.

Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain.

Fine control: microRNA regulation of adult neurogenesis.

Cell types to order: temporal specification of CNS stem cells.

Automatic summarization of changes in biological image sequences using algorithmic information theory.

Baby got brain: Fgf10 sets rostral cortical size.

Sense and serendipity aid RPE generation.

Spred1, a negative regulator of Ras-MAPK-ERK, is enriched in CNS germinal zones, dampens NSC proliferation, and maintains ventricular zone structure.

Joanna Wysocka wins ISSCR Outstanding Young Investigator Award.

Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling.

Translating stem cell studies to the clinic for CNS repair: current state of the art and the need for a Rosetta stone.

Stem cells for retinal replacement therapy.

Vertebrate neural stem cell segmentation, tracking and lineaging with validation and editing.

Adult human RPE can be activated into a multipotent stem cell that produces mesenchymal derivatives.

The effect of long-term release of Shh from implanted biodegradable microspheres on recovery from spinal cord injury in mice.

Molecular characterisation of transport mechanisms at the developing mouse blood-CSF interface: a transcriptome approach.

VCAM1 is essential to maintain the structure of the SVZ niche and acts as an environmental sensor to regulate SVZ lineage progression.

Asymmetric Segregation of the Double-Stranded RNA Binding Protein Staufen2 during Mammalian Neural Stem Cell Divisions Promotes Lineage Progression.

The niche factor syndecan-1 regulates the maintenance and proliferation of neural progenitor cells during mammalian cortical development.

The culture and maintenance of functional retinal pigment epithelial monolayers from adult human eye.

Ophthalmologic stem cell transplantation therapies.

Chronic oxidative stress upregulates Drusen-related protein expression in adult human RPE stem cell-derived RPE cells: a novel culture model for dry AMD.

Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA.

Sustained levels of FGF2 maintain undifferentiated stem cell cultures with biweekly feeding.

Neural stem cells: generating and regenerating the brain.

Human RPE stem cells grown into polarized RPE monolayers on a polyester matrix are maintained after grafting into rabbit subretinal space.

Stem cells for retinal repair.

A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.

CORTECON: a temporal transcriptome analysis of in vitro human cerebral cortex development from human embryonic stem cells.

Visualization and correction of automated segmentation, tracking and lineaging from 5-D stem cell image sequences.

Interaction of amyloid inhibitor proteins with amyloid beta peptides: insight from molecular dynamics simulations.

Multisensory interface for 5D stem cell image volumes.

Slow progression of exudative age related macular degeneration associated with hypertrophy of the retinal pigment epithelium.

It takes a village: constructing the neurogenic niche.

Retinal pigment epithelial cell proliferation.

Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells.

Computational Image Analysis Reveals Intrinsic Multigenerational Differences between Anterior and Posterior Cerebral Cortex Neural Progenitor Cells.

Regenerative Medicine: Solution in Sight.

Human Retinal Pigment Epithelium Stem Cell (RPESC).

Attomole quantification and global profile of RNA modifications: Epitranscriptome of human neural stem cells.

Human Adult Retinal Pigment Epithelial Stem Cell-Derived RPE Monolayers Exhibit Key Physiological Characteristics of Native Tissue.

A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity.

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.

Human RPE Stem Cell-Derived RPE Preserves Photoreceptors in the Royal College of Surgeons Rat: Method for Quantifying the Area of Photoreceptor Sparing.

Automated Measurement of Cobblestone Morphology for Characterizing Stem Cell Derived Retinal Pigment Epithelial Cell Cultures.

In Pursuit of Authenticity: Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Clinical Applications.

LEVER: software tools for segmentation, tracking and lineaging of proliferating cells.

Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.

Making the Most from Changes in Life.

Measuring Process Dynamics and Nuclear Migration for Clones of Neural Progenitor Cells.

Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration.

Lessons Learned from Pioneering Neural Stem Cell Studies.

Stem cell therapies for retinal diseases: recapitulating development to replace degenerated cells.

Factors Released from Endothelial Cells Exposed to Flow Impact Adhesion, Proliferation, and Fate Choice in the Adult Neural Stem Cell Lineage.

Cultivating a Robust Stem Cell Field.

The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue.

Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells.