Mengsu Yang

Kinetic study of various binding modes between human DNA polymerase beta and different DNA substrates by surface-plasmon-resonance biosensor.

Study of substrate-enzyme interaction between immobilized pyridoxamine and recombinant porcine pyridoxal kinase using surface plasmon resonance biosensor.

Syntheses of ruthenium(II) quinonediimine complexes of cyclam and characterization of their DNA-binding activities and cytotoxicity.

Impedance analysis of an electrode-separated piezoelectric sensor as a surface monitoring technique for surfactant adsorption on quartz surface.

Cell docking and on-chip monitoring of cellular reactions with a controlled concentration gradient on a microfluidic device.

Synthesis and biological activity of a platinum(II) 6-phenyl-2,2'-bipyridine complex and its dimeric analogue.

Pyranocoumarins isolated from Peucedanum praeruptorum as differentiation inducers in human leukemic HL-60 cells.

cDNA microarray analysis of gene expression profiles in human fibroblast cells irradiated with red light.

Electrochemical properties of DNA-intercalating doxorubicin and methylene blue on n-hexadecyl mercaptan-doped 5'-thiol-labeled DNA-modified gold electrodes.

Inhibitory actions of genistein in human breast cancer (MCF-7) cells.

Bis-intercalative dinuclear platinum(II) 6-phenyl-2,2'-bipyridine complexes exhibit enhanced DNA affinity but similar cytotoxicity compared to the mononuclear unit.

PDMS-based microfluidic device with multi-height structures fabricated by single-step photolithography using printed circuit board as masters.

Effects of DNA mismatches on binding affinity and kinetics of polymerase-DNA complexes as revealed by surface plasmon resonance biosensor.

Association of Vimentin overexpression and hepatocellular carcinoma metastasis.

Interaction between pyridoxal kinase and pyridoxal-5-phosphate-dependent enzymes.

Hydrodynamic simulation of cell docking in microfluidic channels with different dam structures.

Surface plasmon resonance study of the molecular recognition between polymerase and DNA containing various mismatches and conformational changes of DNA-protein complexes.

Cluster analysis of gene expression data based on self-splitting and merging competitive learning.

Generation of concentration gradient by controlled flow distribution and diffusive mixing in a microfluidic chip.

Trichosanthin's interfacial interactions with phospholipids: a monolayer study.

Impedance analysis of an electrode-separated piezoelectric sensor as a surface-monitoring technique for gelatin adsorption on quartz surface.

Cytotoxicity of three cycloartane triterpenoids from Cimicifuga dahurica.

Water soluble luminescent platinum terpyridine complexes with glycosylated acetylide and arylacetylide ligands: photoluminescent properties and cytotoxicities.

Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation.

Classification of short human exons and introns based on statistical features.

Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-deficient HL-60 cells.

The cytotoxicity of naturally occurring styryl lactones.

Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in HepG2 liver cancer cells.

Effect of WeiJia on carbon tetrachloride induced chronic liver injury.

Anti-cancer activity and mechanisms of 25-anhydrocimigenol-3-O-beta-D-xylopyranoside isolated from Souliea vaginata on hepatomas.

Optical and electrochemical detection techniques for cell-based microfluidic systems.

A low temperature bonding of quartz microfluidic chip for serum lipoproteins analysis.

Dose-dependent cell-based assays in V-shaped microfluidic channels.

Cytotoxic cycloartane triterpene saponins from Actaea asiatica.

Effects of rhDecorin on TGF-beta1 induced human hepatic stellate cells LX-2 activation.

Hypoxia induces the activation of human hepatic stellate cells LX-2 through TGF-beta signaling pathway.

Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.

DNA binding and cytotoxicity of ruthenium(II) and rhenium(I) complexes of 2-amino-4-phenylamino-6-(2-pyridyl)-1,3,5-triazine.

1,25-dihydroxyvitamin D3 induces biphasic NF-kappaB responses during HL-60 leukemia cells differentiation through protein induction and PI3K/Akt-dependent phosphorylation/degradation of IkappaB.

Effect of hypoxia on RAW264.7 macrophages apoptosis and signaling.

Cytotoxic activity of schisandrolic and isoschisandrolic acids involves induction of apoptosis.

Dexamethasone protects RAW264.7 macrophages from growth arrest and apoptosis induced by H2O2 through alteration of gene expression patterns and inhibition of nuclear factor-kappa B (NF-kappaB) activity.

Effects of silicon nanowires on HepG2 cell adhesion and spreading.

Inhibition of biochemical reactions by silicon nanowires through modulating enzyme activities.

Synthesis, cytotoxicity and DNA binding levels of tri-functional mononuclear platinum(II) complexes.

New furostanol saponins from the bulbs of Allium macrostemon Bunge and their cytotoxic activity.

Generation of linear and non-linear concentration gradients along microfluidic channel by microtunnel controlled stepwise addition of sample solution.

Deep proteome profiling of sera from never-smoked lung cancer patients.

Colorimetric oligonucleotide array for genotyping of hepatitis C virus based on the 5' non-coding region.

3-D streamline steering by nodes arrayed in an entangled microfluidic network.

Effective statistical features for coding and non-coding DNA sequence classification for yeast, C. elegans and human.

cDNA microarray analysis of the differentially expressed genes involved in murine pre-osteoclast RAW264.7 cells proliferation stimulated by dexamethasone.

1p31, 7q21 and 18q21 chromosomal aberrations and candidate genes in acquired vinblastine resistance of human cervical carcinoma KB cells.

Synthesis, characterization and antitumor activity of new type binuclear platinum(II) complexes.

Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways.

COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis.

Editorial - analytical science in China.

Gene expression analysis of human promyelocytic leukemia HL-60 cell differentiation and cytotoxicity induced by natural and synthetic retinoids.

Transcriptional analysis of doxorubicin-induced cytotoxicity and resistance in human hepatocellular carcinoma cell lines.

Microfluidic formation of single cell array for parallel analysis of Ca2+ release-activated Ca2+ (CRAC) channel activation and inhibition.

beta2- and beta3-, but not beta1-adrenergic receptors are involved in osteogenesis of mouse mesenchymal stem cells via cAMP/PKA signaling.

Linkage of angiotensinogen gene polymorphisms with hypertension in a sibling study of Hong Kong Chinese.

Inhibition of proliferation and differentiation of mesenchymal stem cells by carboxylated carbon nanotubes.

Cell adhesion and spreading behavior on vertically aligned silicon nanowire arrays.

Beta-adrenergic signals regulate adipogenesis of mouse mesenchymal stem cells via cAMP/PKA pathway.

Covalent conjugation of multi-walled carbon nanotubes with proteins.

Covalently linked deoxyribonucleic acid with multi-walled carbon nanotubes: synthesis and characterization.

Effects of carbon nanotubes on the proliferation and differentiation of primary osteoblasts.

Effect of carbon nanotubes on HepG2 adhesion and spreading.

A microfluidic device with microbead array for sensitive virus detection and genotyping using quantum dots as fluorescence labels.

Patterned growth of vertically aligned silicon nanowire arrays for label-free DNA detection using surface-enhanced Raman spectroscopy.

Real-time monitoring of suspension cell-cell communication using an integrated microfluidics.

DNA expression profiles of non-small cell lung cancer.

Prevalence and genotype distribution of cervical human papillomavirus infection in Macao.

Gold nanoparticles promote osteogenic differentiation of mesenchymal stem cells through p38 MAPK pathway.

The structure and function of ribonuclease A upon interacting with carbon nanotubes.

Integrated sieving microstructures on microchannels for biological cell trapping and droplet formation.

Multienzyme-nanoparticles amplification for sensitive virus genotyping in microfluidic microbeads array using Au nanoparticle probes and quantum dots as labels.

Danshen-Gegen decoction exerts proliferative effect on rat cardiac myoblasts H9c2 via MAPK and insulin pathways.

Transcriptional profiling of human skin fibroblast cell line Hs27 induced by herbal formula Astragali Radix and Rehmanniae Radix.

The effects of Ce on the proliferation, osteogenic differentiation and mineralization function of MC3T3-E1 cells in vitro.

Imipramine inhibits adipogenic differentiation in both 3T3-L1 preadipocytes and mouse marrow stromal cells.

Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosis.

The dual-effects of LaCl₃ on the proliferation, osteogenic differentiation, and mineralization of MC3T3-E1 cells.

Herbal formula Astragali Radix and Rehmanniae Radix exerted wound healing effect on human skin fibroblast cell line Hs27 via the activation of transformation growth factor (TGF-β) pathway and promoting extracellular matrix (ECM) deposition.

Screen printing of solder resist as master substrates for fabrication of multi-level microfluidic channels and flask-shaped microstructures for cell-based applications.

Microfluidics study of intracellular calcium response to mechanical stimulation on single suspension cells.

Detection of cancer biomarkers by piezoelectric biosensor using PZT ceramic resonator as the transducer.

Peptide-bridged assembly of hybrid nanomaterial and its application for caspase-3 detection.

Coupling gold nanoparticles to silica nanoparticles through disulfide bonds for glutathione detection.

On-site formation of emulsions by controlled air plugs.

Nanoparticle-based signal generation and amplification in microfluidic devices for bioanalysis.

Label-free detection of endocrine disrupting chemicals by integrating a competitive binding assay with a piezoelectric ceramic resonator.

Single layer linear array of microbeads for multiplexed analysis of DNA and proteins.

Reorganization of cytoskeleton and transient activation of Ca2+ channels in mesenchymal stem cells cultured on silicon nanowire arrays.

A dual-mode nanosensor based on carbon quantum dots and gold nanoparticles for discriminative detection of glutathione in human plasma.

Activation of multiple signaling pathways during the differentiation of mesenchymal stem cells cultured in a silicon nanowire microenvironment.

Gold nanoparticles stimulate differentiation and mineralization of primary osteoblasts through the ERK/MAPK signaling pathway.

A microfluidic linear node array for the study of protein-ligand interactions.

Synthesis, characterization and biomedical application of multifunctional luminomagnetic core-shell nanoparticles.

Microfluidic Platform for Studying Chemotaxis of Adhesive Cells Revealed a Gradient-Dependent Migration and Acceleration of Cancer Stem Cells.

Gene expression analysis of human promyelocytic leukemia HL-60 cell differentiation and cytotoxicity induced by natural and synthetic retinoids.

Flavonoids of Herba Epimedii stimulate osteogenic differentiation and suppress adipogenic differentiation of primary mesenchymal stem cells via estrogen receptor pathway.

Two chiroptical modes of silver nanospirals.

Au Nanoparticles Decorated TiO2 Nanotube Arrays as a Recyclable Sensor for Photoenhanced Electrochemical Detection of Bisphenol A.

Monitoring the intracellular calcium response to a dynamic hypertonic environment.

Icariin Stimulates Differentiation and Suppresses Adipocytic Transdifferentiation of Primary Osteoblasts Through Estrogen Receptor-Mediated Pathway.

High sensitivity plasmonic biosensor based on nanoimprinted quasi 3D nanosquares for cell detection.

Cell migration microfluidics for electrotaxis-based heterogeneity study of lung cancer cells.

Chemoresistant lung cancer stem cells display high DNA repair capability to remove cisplatin-induced DNA damage.

Effects of direct current electric fields on lung cancer cell electrotaxis in a PMMA-based microfluidic device.