Department of Biomedical Sciences,
Key Laboratory of Biochip Technology,
Biotech and Health Centre,
Department of Biomedical Sciences, Key Laboratory of Biochip Technology, Biotech and Health Centre
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Kinetic study of various binding modes between human DNA polymerase beta and different DNA substrates by surface-plasmon-resonance biosensor.
The Biochemical journal Jan, 2002 | Pubmed ID: 11772403
Study of substrate-enzyme interaction between immobilized pyridoxamine and recombinant porcine pyridoxal kinase using surface plasmon resonance biosensor.
Biochimica et biophysica acta Apr, 2002 | Pubmed ID: 11983425
Syntheses of ruthenium(II) quinonediimine complexes of cyclam and characterization of their DNA-binding activities and cytotoxicity.
Inorganic chemistry Jun, 2002 | Pubmed ID: 12054995
Impedance analysis of an electrode-separated piezoelectric sensor as a surface monitoring technique for surfactant adsorption on quartz surface.
The Analyst Jul, 2002 | Pubmed ID: 12173654
Cell docking and on-chip monitoring of cellular reactions with a controlled concentration gradient on a microfluidic device.
Analytical chemistry Aug, 2002 | Pubmed ID: 12199565
Synthesis and biological activity of a platinum(II) 6-phenyl-2,2'-bipyridine complex and its dimeric analogue.
Chembiochem : a European journal of chemical biology Jan, 2003 | Pubmed ID: 12512077
Pyranocoumarins isolated from Peucedanum praeruptorum as differentiation inducers in human leukemic HL-60 cells.
Planta medica Mar, 2003 | Pubmed ID: 12677525
cDNA microarray analysis of gene expression profiles in human fibroblast cells irradiated with red light.
The Journal of investigative dermatology May, 2003 | Pubmed ID: 12713592
Electrochemical properties of DNA-intercalating doxorubicin and methylene blue on n-hexadecyl mercaptan-doped 5'-thiol-labeled DNA-modified gold electrodes.
Biosensors & bioelectronics Jul, 2003 | Pubmed ID: 12713910
Inhibitory actions of genistein in human breast cancer (MCF-7) cells.
Biochimica et biophysica acta Jul, 2003 | Pubmed ID: 12853125
Bis-intercalative dinuclear platinum(II) 6-phenyl-2,2'-bipyridine complexes exhibit enhanced DNA affinity but similar cytotoxicity compared to the mononuclear unit.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Sep, 2003 | Pubmed ID: 12884091
PDMS-based microfluidic device with multi-height structures fabricated by single-step photolithography using printed circuit board as masters.
The Analyst Sep, 2003 | Pubmed ID: 14529020
Effects of DNA mismatches on binding affinity and kinetics of polymerase-DNA complexes as revealed by surface plasmon resonance biosensor.
The Analyst Sep, 2003 | Pubmed ID: 14529025
Association of Vimentin overexpression and hepatocellular carcinoma metastasis.
Oncogene Jan, 2004 | Pubmed ID: 14647434
Interaction between pyridoxal kinase and pyridoxal-5-phosphate-dependent enzymes.
Journal of biochemistry Nov, 2003 | Pubmed ID: 14688239
Hydrodynamic simulation of cell docking in microfluidic channels with different dam structures.
Lab on a chip Feb, 2004 | Pubmed ID: 15007441
Surface plasmon resonance study of the molecular recognition between polymerase and DNA containing various mismatches and conformational changes of DNA-protein complexes.
Biosensors & bioelectronics May, 2004 | Pubmed ID: 15046752
Cluster analysis of gene expression data based on self-splitting and merging competitive learning.
IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society Mar, 2004 | Pubmed ID: 15055797
Generation of concentration gradient by controlled flow distribution and diffusive mixing in a microfluidic chip.
Lab on a chip Aug, 2002 | Pubmed ID: 15100827
Trichosanthin's interfacial interactions with phospholipids: a monolayer study.
Colloids and surfaces. B, Biointerfaces Dec, 2004 | Pubmed ID: 15556338
Impedance analysis of an electrode-separated piezoelectric sensor as a surface-monitoring technique for gelatin adsorption on quartz surface.
Journal of colloid and interface science Jan, 2005 | Pubmed ID: 15571695
Cytotoxicity of three cycloartane triterpenoids from Cimicifuga dahurica.
Cancer letters Aug, 2005 | Pubmed ID: 16004933
Water soluble luminescent platinum terpyridine complexes with glycosylated acetylide and arylacetylide ligands: photoluminescent properties and cytotoxicities.
Chemical communications (Cambridge, England) Oct, 2005 | Pubmed ID: 16175289
Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation.
Biochemical pharmacology Nov, 2005 | Pubmed ID: 16181613
Classification of short human exons and introns based on statistical features.
Physical review. E, Statistical, nonlinear, and soft matter physics Jun, 2003 | Pubmed ID: 16241270
Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-deficient HL-60 cells.
Cancer letters Sep, 2006 | Pubmed ID: 16316721
The cytotoxicity of naturally occurring styryl lactones.
Phytomedicine : international journal of phytotherapy and phytopharmacology Feb, 2006 | Pubmed ID: 16428026
Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in HepG2 liver cancer cells.
Cancer letters Sep, 2006 | Pubmed ID: 16458429
Effect of WeiJia on carbon tetrachloride induced chronic liver injury.
World journal of gastroenterology Mar, 2006 | Pubmed ID: 16609998
Anti-cancer activity and mechanisms of 25-anhydrocimigenol-3-O-beta-D-xylopyranoside isolated from Souliea vaginata on hepatomas.
Anti-cancer drugs Jun, 2006 | Pubmed ID: 16702811
Optical and electrochemical detection techniques for cell-based microfluidic systems.
Analytical and bioanalytical chemistry Mar, 2006 | Pubmed ID: 16795144
A low temperature bonding of quartz microfluidic chip for serum lipoproteins analysis.
Biomedical microdevices Sep, 2006 | Pubmed ID: 16799750
Dose-dependent cell-based assays in V-shaped microfluidic channels.
Lab on a chip Jul, 2006 | Pubmed ID: 16804597
Cytotoxic cycloartane triterpene saponins from Actaea asiatica.
Journal of natural products Oct, 2006 | Pubmed ID: 17067171
Effects of rhDecorin on TGF-beta1 induced human hepatic stellate cells LX-2 activation.
Biochimica et biophysica acta Nov, 2006 | Pubmed ID: 17067743
Hypoxia induces the activation of human hepatic stellate cells LX-2 through TGF-beta signaling pathway.
FEBS letters Jan, 2007 | Pubmed ID: 17187782
Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.
Molecular immunology Apr, 2007 | Pubmed ID: 17240450
DNA binding and cytotoxicity of ruthenium(II) and rhenium(I) complexes of 2-amino-4-phenylamino-6-(2-pyridyl)-1,3,5-triazine.
Inorganic chemistry Feb, 2007 | Pubmed ID: 17257015
1,25-dihydroxyvitamin D3 induces biphasic NF-kappaB responses during HL-60 leukemia cells differentiation through protein induction and PI3K/Akt-dependent phosphorylation/degradation of IkappaB.
Experimental cell research May, 2007 | Pubmed ID: 17397830
Effect of hypoxia on RAW264.7 macrophages apoptosis and signaling.
Toxicology Jun, 2007 | Pubmed ID: 17416447
Cytotoxic activity of schisandrolic and isoschisandrolic acids involves induction of apoptosis.
Chemotherapy , 2007 | Pubmed ID: 17496413
Dexamethasone protects RAW264.7 macrophages from growth arrest and apoptosis induced by H2O2 through alteration of gene expression patterns and inhibition of nuclear factor-kappa B (NF-kappaB) activity.
Toxicology Jul, 2007 | Pubmed ID: 17499901
Effects of silicon nanowires on HepG2 cell adhesion and spreading.
Chembiochem : a European journal of chemical biology Jul, 2007 | Pubmed ID: 17525918
Inhibition of biochemical reactions by silicon nanowires through modulating enzyme activities.
Chembiochem : a European journal of chemical biology Jul, 2007 | Pubmed ID: 17566125
Synthesis, cytotoxicity and DNA binding levels of tri-functional mononuclear platinum(II) complexes.
European journal of medicinal chemistry Feb, 2008 | Pubmed ID: 17587465
New furostanol saponins from the bulbs of Allium macrostemon Bunge and their cytotoxic activity.
Die Pharmazie Jul, 2007 | Pubmed ID: 17718198
Generation of linear and non-linear concentration gradients along microfluidic channel by microtunnel controlled stepwise addition of sample solution.
Lab on a chip Oct, 2007 | Pubmed ID: 17896024
Deep proteome profiling of sera from never-smoked lung cancer patients.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Oct, 2007 | Pubmed ID: 17913442
Colorimetric oligonucleotide array for genotyping of hepatitis C virus based on the 5' non-coding region.
Clinica chimica acta; international journal of clinical chemistry Feb, 2008 | Pubmed ID: 17976565
3-D streamline steering by nodes arrayed in an entangled microfluidic network.
Lab on a chip Dec, 2007 | Pubmed ID: 18030391
Effective statistical features for coding and non-coding DNA sequence classification for yeast, C. elegans and human.
International journal of bioinformatics research and applications , 2005 | Pubmed ID: 18048129
cDNA microarray analysis of the differentially expressed genes involved in murine pre-osteoclast RAW264.7 cells proliferation stimulated by dexamethasone.
Life sciences Jan, 2008 | Pubmed ID: 18083200
1p31, 7q21 and 18q21 chromosomal aberrations and candidate genes in acquired vinblastine resistance of human cervical carcinoma KB cells.
Oncology reports May, 2008 | Pubmed ID: 18425371
Synthesis, characterization and antitumor activity of new type binuclear platinum(II) complexes.
European journal of medicinal chemistry May, 2009 | Pubmed ID: 18524422
Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways.
Proteomics Aug, 2008 | Pubmed ID: 18615425
COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2008 | Pubmed ID: 18698024
Editorial - analytical science in China.
The Analyst Sep, 2008 | Pubmed ID: 18709184
Gene expression analysis of human promyelocytic leukemia HL-60 cell differentiation and cytotoxicity induced by natural and synthetic retinoids.
Life sciences Apr, 2009 | Pubmed ID: 19302803
Transcriptional analysis of doxorubicin-induced cytotoxicity and resistance in human hepatocellular carcinoma cell lines.
Liver international : official journal of the International Association for the Study of the Liver Oct, 2009 | Pubmed ID: 19627484
Microfluidic formation of single cell array for parallel analysis of Ca2+ release-activated Ca2+ (CRAC) channel activation and inhibition.
Analytical biochemistry Jan, 2010 | Pubmed ID: 19751694
beta2- and beta3-, but not beta1-adrenergic receptors are involved in osteogenesis of mouse mesenchymal stem cells via cAMP/PKA signaling.
Archives of biochemistry and biophysics Apr, 2010 | Pubmed ID: 20138019
Linkage of angiotensinogen gene polymorphisms with hypertension in a sibling study of Hong Kong Chinese.
Journal of hypertension Jun, 2010 | Pubmed ID: 20216084
Inhibition of proliferation and differentiation of mesenchymal stem cells by carboxylated carbon nanotubes.
ACS nano Apr, 2010 | Pubmed ID: 20218664
Cell adhesion and spreading behavior on vertically aligned silicon nanowire arrays.
ACS applied materials & interfaces Jan, 2009 | Pubmed ID: 20355748
Beta-adrenergic signals regulate adipogenesis of mouse mesenchymal stem cells via cAMP/PKA pathway.
Molecular and cellular endocrinology Jul, 2010 | Pubmed ID: 20363288
Covalent conjugation of multi-walled carbon nanotubes with proteins.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20422377
Covalently linked deoxyribonucleic acid with multi-walled carbon nanotubes: synthesis and characterization.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20422378
Effects of carbon nanotubes on the proliferation and differentiation of primary osteoblasts.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20422380
Effect of carbon nanotubes on HepG2 adhesion and spreading.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20422390
A microfluidic device with microbead array for sensitive virus detection and genotyping using quantum dots as fluorescence labels.
Biosensors & bioelectronics Jul, 2010 | Pubmed ID: 20483585
Patterned growth of vertically aligned silicon nanowire arrays for label-free DNA detection using surface-enhanced Raman spectroscopy.
Analytical and bioanalytical chemistry Aug, 2010 | Pubmed ID: 20563793
Real-time monitoring of suspension cell-cell communication using an integrated microfluidics.
Lab on a chip Sep, 2010 | Pubmed ID: 20614062
DNA expression profiles of non-small cell lung cancer.
Zhongguo fei ai za zhi = Chinese journal of lung cancer Jan, 2009 | Pubmed ID: 20712950
Prevalence and genotype distribution of cervical human papillomavirus infection in Macao.
Journal of medical virology Oct, 2010 | Pubmed ID: 20827770
Gold nanoparticles promote osteogenic differentiation of mesenchymal stem cells through p38 MAPK pathway.
ACS nano Nov, 2010 | Pubmed ID: 21028783
The structure and function of ribonuclease A upon interacting with carbon nanotubes.
Nanotechnology Mar, 2008 | Pubmed ID: 21817664
Integrated sieving microstructures on microchannels for biological cell trapping and droplet formation.
Lab on a chip Oct, 2011 | Pubmed ID: 21853193
Multienzyme-nanoparticles amplification for sensitive virus genotyping in microfluidic microbeads array using Au nanoparticle probes and quantum dots as labels.
Biosensors & bioelectronics Nov, 2011 | Pubmed ID: 21872460
Danshen-Gegen decoction exerts proliferative effect on rat cardiac myoblasts H9c2 via MAPK and insulin pathways.
Journal of ethnopharmacology Oct, 2011 | Pubmed ID: 21907783
Transcriptional profiling of human skin fibroblast cell line Hs27 induced by herbal formula Astragali Radix and Rehmanniae Radix.
Journal of ethnopharmacology Dec, 2011 | Pubmed ID: 22075453
The effects of Ce on the proliferation, osteogenic differentiation and mineralization function of MC3T3-E1 cells in vitro.
Biological trace element research Nov, 2012 | Pubmed ID: 22528784
Imipramine inhibits adipogenic differentiation in both 3T3-L1 preadipocytes and mouse marrow stromal cells.
Journal of genetics and genomics = Yi chuan xue bao Apr, 2012 | Pubmed ID: 22546539
Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosis.
Biochimie Dec, 2012 | Pubmed ID: 22796380
The dual-effects of LaCl₃ on the proliferation, osteogenic differentiation, and mineralization of MC3T3-E1 cells.
Biological trace element research Dec, 2012 | Pubmed ID: 22886987
Herbal formula Astragali Radix and Rehmanniae Radix exerted wound healing effect on human skin fibroblast cell line Hs27 via the activation of transformation growth factor (TGF-β) pathway and promoting extracellular matrix (ECM) deposition.
Phytomedicine : international journal of phytotherapy and phytopharmacology Dec, 2012 | Pubmed ID: 23083814
Screen printing of solder resist as master substrates for fabrication of multi-level microfluidic channels and flask-shaped microstructures for cell-based applications.
Biosensors & bioelectronics Mar, 2013 | Pubmed ID: 23122749
Microfluidics study of intracellular calcium response to mechanical stimulation on single suspension cells.
Lab on a chip Mar, 2013 | Pubmed ID: 23403699
Detection of cancer biomarkers by piezoelectric biosensor using PZT ceramic resonator as the transducer.
Biosensors & bioelectronics Aug, 2013 | Pubmed ID: 23542085
Peptide-bridged assembly of hybrid nanomaterial and its application for caspase-3 detection.
ACS applied materials & interfaces Jul, 2013 | Pubmed ID: 23806127
Coupling gold nanoparticles to silica nanoparticles through disulfide bonds for glutathione detection.
Nanotechnology Sep, 2013 | Pubmed ID: 23974169
On-site formation of emulsions by controlled air plugs.
Small (Weinheim an der Bergstrasse, Germany) Feb, 2014 | Pubmed ID: 24030982
Nanoparticle-based signal generation and amplification in microfluidic devices for bioanalysis.
The Analyst Nov, 2013 | Pubmed ID: 24067742
Label-free detection of endocrine disrupting chemicals by integrating a competitive binding assay with a piezoelectric ceramic resonator.
Biosensors & bioelectronics Mar, 2014 | Pubmed ID: 24201004
Single layer linear array of microbeads for multiplexed analysis of DNA and proteins.
Biosensors & bioelectronics Apr, 2014 | Pubmed ID: 24287420
Reorganization of cytoskeleton and transient activation of Ca2+ channels in mesenchymal stem cells cultured on silicon nanowire arrays.
ACS applied materials & interfaces Dec, 2013 | Pubmed ID: 24308382
A dual-mode nanosensor based on carbon quantum dots and gold nanoparticles for discriminative detection of glutathione in human plasma.
Biosensors & bioelectronics Jun, 2014 | Pubmed ID: 24462829
Activation of multiple signaling pathways during the differentiation of mesenchymal stem cells cultured in a silicon nanowire microenvironment.
Nanomedicine : nanotechnology, biology, and medicine Aug, 2014 | Pubmed ID: 24566272
Gold nanoparticles stimulate differentiation and mineralization of primary osteoblasts through the ERK/MAPK signaling pathway.
Materials science & engineering. C, Materials for biological applications Sep, 2014 | Pubmed ID: 25063094
A microfluidic linear node array for the study of protein-ligand interactions.
Lab on a chip Oct, 2014 | Pubmed ID: 25140880
Synthesis, characterization and biomedical application of multifunctional luminomagnetic core-shell nanoparticles.
Materials science & engineering. C, Materials for biological applications Jan, 2015 | Pubmed ID: 25491957
Microfluidic Platform for Studying Chemotaxis of Adhesive Cells Revealed a Gradient-Dependent Migration and Acceleration of Cancer Stem Cells.
Analytical chemistry Jul, 2015 | Pubmed ID: 26087892
Gene expression analysis of human promyelocytic leukemia HL-60 cell differentiation and cytotoxicity induced by natural and synthetic retinoids.
Life sciences Apr, 2009 | Pubmed ID: 26324987
Flavonoids of Herba Epimedii stimulate osteogenic differentiation and suppress adipogenic differentiation of primary mesenchymal stem cells via estrogen receptor pathway.
Pharmaceutical biology Oct, 2015 | Pubmed ID: 26453492
Two chiroptical modes of silver nanospirals.
Nanotechnology Mar, 2016 | Pubmed ID: 26876361
Au Nanoparticles Decorated TiO2 Nanotube Arrays as a Recyclable Sensor for Photoenhanced Electrochemical Detection of Bisphenol A.
Environmental science & technology Apr, 2016 | Pubmed ID: 27002339
Monitoring the intracellular calcium response to a dynamic hypertonic environment.
Scientific reports Mar, 2016 | Pubmed ID: 27004604
Icariin Stimulates Differentiation and Suppresses Adipocytic Transdifferentiation of Primary Osteoblasts Through Estrogen Receptor-Mediated Pathway.
Calcified tissue international Aug, 2016 | Pubmed ID: 27061090
High sensitivity plasmonic biosensor based on nanoimprinted quasi 3D nanosquares for cell detection.
Nanotechnology Jul, 2016 | Pubmed ID: 27275952
Cell migration microfluidics for electrotaxis-based heterogeneity study of lung cancer cells.
Biosensors & bioelectronics Mar, 2017 | Pubmed ID: 27816579
Chemoresistant lung cancer stem cells display high DNA repair capability to remove cisplatin-induced DNA damage.
British journal of pharmacology Feb, 2017 | Pubmed ID: 27933604
Effects of direct current electric fields on lung cancer cell electrotaxis in a PMMA-based microfluidic device.
Analytical and bioanalytical chemistry Jan, 2017 | Pubmed ID: 28078410
Shan-Shan Li*,1,
Carman K. M. Ip*,1,
Matthew Y. H. Tang*,2,
Samuel K. H. Sy2,
Susan Yung3,
Tak-Mao Chan3,
Mengsu Yang4,
Ho Cheung Shum2,
Alice S.T. Wong1
1School of Biological Sciences, University of Hong Kong,
2Department of Mechanical Engineering, University of Hong Kong,
3Department of Medicine, University of Hong Kong,
4Department of Biomedical Sciences, Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institutes of City University of Hong Kong
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