Technology Advancement and Commercialization
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Back to the future: inhaled drug products.
Journal of pharmaceutical sciences Apr, 2013 | Pubmed ID: 23381932
New mechanisms to explain the effects of added lactose fines on the dispersion performance of adhesive mixtures for inhalation.
PloS one , 2014 | Pubmed ID: 24489969
Lipid-based carriers for pulmonary products: preclinical development and case studies in humans.
Advanced drug delivery reviews Aug, 2014 | Pubmed ID: 24819218
Controlled delivery of inhaled therapeutic agents.
Journal of controlled release : official journal of the Controlled Release Society Sep, 2014 | Pubmed ID: 24907604
Scale of health: indices of safety and efficacy in the evolving environment of large biological datasets.
Pharmaceutical research Sep, 2014 | Pubmed ID: 24919930
The role of particle physico-chemical properties in pulmonary drug delivery for tuberculosis therapy.
Journal of microencapsulation , 2014 | Pubmed ID: 25090595
Targeting inhaled therapy beyond the lungs.
Respiration; international review of thoracic diseases , 2014 | Pubmed ID: 25277464
In vitro dry powder inhaler formulation performance considerations.
Journal of controlled release : official journal of the Controlled Release Society Feb, 2015 | Pubmed ID: 25497311
Inhaled drug treatment for tuberculosis: Past progress and future prospects.
Journal of controlled release : official journal of the Controlled Release Society Oct, 2016 | Pubmed ID: 26596254
Real-Time Investigation of Tuberculosis Transmission: Developing the Respiratory Aerosol Sampling Chamber (RASC).
PloS one , 2016 | Pubmed ID: 26807816
A dry powder combination of pyrazinoic acid and its n-propyl ester for aerosol administration to animals.
International journal of pharmaceutics Dec, 2016 | Pubmed ID: 27130363
Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis.
Pharmaceutical research Oct, 2016 | Pubmed ID: 27351427
Nanomaterial Drug Products: Manufacturing and Analytical Perspectives.
The AAPS journal Jan, 2017 | Pubmed ID: 27822601
Systems biology for organotypic cell cultures.
ALTEX Nov, 2016 | Pubmed ID: 27846345
Influence of Formulation Factors on the Aerosol Performance of Suspension and Solution Metered Dose Inhalers: A Systematic Approach.
The AAPS journal Sep, 2017 | Pubmed ID: 28593514
Density and Shape Factor Terms in Stokes' Equation for Aerodynamic Behavior of Aerosols.
Journal of pharmaceutical sciences Mar, 2018 | Pubmed ID: 29154770
Reproducibility, sharing and progress in nanomaterial databases.
Nature nanotechnology Dec, 2017 | Pubmed ID: 29209007
Co-suspension delivery technology in pressurized metered-dose inhalers for multi-drug dosing in the treatment of respiratory diseases.
Respiratory medicine Jan, 2018 | Pubmed ID: 29413503
Effects of Formulation Variables on Lung Dosimetry of Albuterol Sulfate Suspension and Beclomethasone Dipropionate Solution Metered Dose Inhalers.
AAPS PharmSciTech Jul, 2018 | Pubmed ID: 29858973
Pharmacokinetics and pharmacodynamics of high doses of inhaled dry powder drugs.
International journal of pharmaceutics Oct, 2018 | Pubmed ID: 30077761
Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis.
PloS one , 2018 | Pubmed ID: 30261007
Exploiting machine learning for end-to-end drug discovery and development.
Nature materials May, 2019 | Pubmed ID: 31000803
A Spray-Dried Combination of Capreomycin and CPZEN-45 for Inhaled Tuberculosis Therapy.
Journal of pharmaceutical sciences Oct, 2019 | Pubmed ID: 31152746
Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599.
Pharmaceutical research Jul, 2019 | Pubmed ID: 31321552
Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies.
Tuberculosis (Edinburgh, Scotland) Jul, 2019 | Pubmed ID: 31378268
Why Wait? The Case for Treating Tuberculosis with Inhaled Drugs.
Pharmaceutical research Oct, 2019 | Pubmed ID: 31650321
Emerging trends in inhaled drug delivery.
Advanced drug delivery reviews , 2020 | Pubmed ID: 32663488
Synergistic drug combinations and machine learning for drug repurposing in chordoma.
Scientific reports Jul, 2020 | Pubmed ID: 32737414
Designing inhalable metal organic frameworks for pulmonary tuberculosis treatment and theragnostics via spray drying.
Chemical communications (Cambridge, England) Nov, 2020 | Pubmed ID: 33025961
A mechanism-based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID-19 treatment in humans.
CPT: pharmacometrics & systems pharmacology 02, 2021 | Pubmed ID: 33296558
User-life of ICS/LABA inhaler devices should be considered when prescribed as relievers.
The European respiratory journal Jan, 2021 | Pubmed ID: 33446577
Microfluidic and Organ-on-a-Chip Approaches to Investigate Cellular and Microenvironmental Contributions to Cardiovascular Function and Pathology.
Frontiers in bioengineering and biotechnology , 2021 | Pubmed ID: 33614613
Inhaled antibodies: Quality and performance considerations.
Human vaccines & immunotherapeutics Apr, 2022 | Pubmed ID: 34191682
A technology evaluation of CVT-301 (Inbrija): an inhalable therapy for treatment of Parkinson's disease.
Expert opinion on drug delivery Nov, 2021 | Pubmed ID: 34311641
Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis.
ACS infectious diseases Oct, 2021 | Pubmed ID: 34546724
In vitro-in vivo correlation of pharmaceutical aerosols.
Advanced drug delivery reviews Dec, 2021 | Pubmed ID: 34710531
COVID-19 symptoms are reduced by targeted hydration of the nose, larynx and trachea.
Scientific reports Mar, 2022 | Pubmed ID: 35351914
Nanoformulated Remdesivir with Extremely Low Content of Poly(2-oxazoline)-Based Stabilizer for Aerosol Treatment of COVID-19.
Macromolecular bioscience Aug, 2022 | Pubmed ID: 35526106
Efficacy of inhaled CPZEN-45 in treating tuberculosis in the guinea pig.
Tuberculosis (Edinburgh, Scotland) Jul, 2022 | Pubmed ID: 35588549
Optimization and Scale Up of Spray Dried CPZEN-45 Aerosol Powders for Inhaled Tuberculosis Treatment.
Pharmaceutical research Dec, 2022 | Pubmed ID: 36114362
Multiple approaches to repurposing drugs for neuroblastoma.
Bioorganic & medicinal chemistry Nov, 2022 | Pubmed ID: 36208544
Stable nebulization and muco-trapping properties of regdanvimab/IN-006 support its development as a potent, dose-saving inhaled therapy for COVID-19.
Bioengineering & translational medicine Aug, 2022 | Pubmed ID: 36248234
Spray dried tigecycline dry powder aerosols for the treatment of Nontuberculous mycobacterial pulmonary infections.
Tuberculosis (Edinburgh, Scotland) Mar, 2023 | Pubmed ID: 36716525
Characterization of spectinamide 1599 efficacy against different mycobacterial phenotypes.
Tuberculosis (Edinburgh, Scotland) May, 2023 | Pubmed ID: 37120915
Preparation Strategies of the Anti-Mycobacterial Drug Bedaquiline for Intrapulmonary Routes of Administration.
Pharmaceuticals (Basel, Switzerland) May, 2023 | Pubmed ID: 37242512
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics.
Pharmaceutics Jun, 2023 | Pubmed ID: 37376207
Pharmacokinetic Considerations for Optimizing Inhaled Spray-Dried Pyrazinoic Acid Formulations.
Molecular pharmaceutics Aug, 2023 | Pubmed ID: 37590399