Katherine M. Kocan

Conservation of major surface protein 1 genes of Anaplasma marginale during cyclic transmission between ticks and cattle.

Infection of tick cells and bovine erythrocytes with one genotype of the intracellular ehrlichia Anaplasma marginale excludes infection with other genotypes.

Effect of tetracycline on development of Anaplasma marginale in cultured Ixodes scapularis cells.

Phylogeography of New World isolates of Anaplasma marginale based on major surface protein sequences.

Vaccination of cattle with Anaplasma marginale derived from tick cell culture and bovine erythrocytes followed by challenge-exposure with infected ticks.

Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cells.

Infection exclusion of the rickettsial pathogen anaplasma marginale in the tick vector Dermacentor variabilis.

Antibodies to Anaplasma marginale major surface proteins 1a and 1b inhibit infectivity for cultured tick cells.

Identification of protective antigens for the control of Ixodes scapularis infestations using cDNA expression library immunization.

Co-feeding studies of ticks infected with Anaplasma marginale.

Applications of a cell culture system for studying the interaction of Anaplasma marginale with tick cells.

Anaplasma marginale msp1alpha genotypes evolved under positive selection pressure but are not markers for geographic isolates.

Characterization of Anaplasma marginale isolated from North American bison.

Antigens and alternatives for control of Anaplasma marginale infection in cattle.

Adaptations of the tick-borne pathogen, Anaplasma marginale, for survival in cattle and ticks.

Advances in the identification and characterization of protective antigens for recombinant vaccines against tick infestations.

Mapping of B-cell epitopes in the N-terminal repeated peptides of Anaplasma marginale major surface protein 1a and characterization of the humoral immune response of cattle immunized with recombinant and whole organism antigens.

Differential expression of the msp1alpha gene of Anaplasma marginale occurs in bovine erythrocytes and tick cells.

Adhesion of outer membrane proteins containing tandem repeats of Anaplasma and Ehrlichia species (Rickettsiales: Anaplasmataceae) to tick cells.

Glycosylation of Anaplasma marginale major surface protein 1a and its putative role in adhesion to tick cells.

Genetic diversity and molecular phylogeny of Anaplasma marginale isolates from Minas Gerais, Brazil.

Anaplasma infection in free-ranging Iberian red deer in the region of Castilla-La Mancha, Spain.

Concurrent infections with vector-borne pathogens associated with fatal hemolytic anemia in a cattle herd in Switzerland.

Identification of a novel Anaplasma marginale appendage-associated protein that localizes with actin filaments during intraerythrocytic infection.

Recent studies on the characterization of Anaplasma marginale isolated from North American bison.

Characterization of genetic diversity in Dermacentor andersoni (Acari: Ixodidae) with body size and weight polymorphism.

Comparison of three oxytetracycline regimes for the treatment of persistent Anaplasma marginale infections in beef cattle.

Sequence analysis of the msp4 gene of Anaplasma phagocytophilum strains.

Gene expression profiling of human promyelocytic cells in response to infection with Anaplasma phagocytophilum.

Seroprevalence of anaplasmosis among cattle in Switzerland in 1998 and 2003: no evidence of an emerging disease.

RNA interference screening in ticks for identification of protective antigens.

bptA (bbe16) is essential for the persistence of the Lyme disease spirochete, Borrelia burgdorferi, in its natural tick vector.

Characterization of three Ixodes scapularis cDNAs protective against tick infestations.

Serologic and molecular characterization of Anaplasma species infection in farm animals and ticks from Sicily.

Vaccination with recombinant tick antigens for the control of Ixodes scapularis adult infestations.

Genetic diversity of anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development.

Capillary tube feeding system for studying tick-pathogen interactions of Dermacentor variabilis (Acari: Ixodidae) and Anaplasma marginale (Rickettsiales: Anaplasmataceae).

Potential vertebrate reservoir hosts and invertebrate vectors of Anaplasma marginale and A. phagocytophilum in central Spain.

Genes differentially expressed in oropharyngeal tonsils and mandibular lymph nodes of tuberculous and nontuberculous European wild boars naturally exposed to Mycobacterium bovis.

Synergistic effect of silencing the expression of tick protective antigens 4D8 and Rs86 in Rhipicephalus sanguineus by RNA interference.

The tick protective antigen, 4D8, is a conserved protein involved in modulation of tick blood ingestion and reproduction.

Autocidal control of ticks by silencing of a single gene by RNA interference.

Characterization of selected genes upregulated in non-tuberculous European wild boar as possible correlates of resistance to Mycobacterium bovis infection.

Reduction of tick infections with Anaplasma marginale and A. phagocytophilum by targeting the tick protective antigen subolesin.

Genetic characterization of Anaplasma ovis strains from bighorn sheep in Montana.

Molecular characterization of Anaplasma platys strains from dogs in Sicily, Italy.

Tick control: further thoughts on a research agenda.

Sequence analysis of the msp4 gene of Anaplasma ovis strains.

Analysis of world strains of Anaplasma marginale using major surface protein 1a repeat sequences.

Molecular epidemiology of human and bovine anaplasmosis in southern Europe.

Anaplasmosis: focusing on host-vector-pathogen interactions for vaccine development.

Proteomic and transcriptomic analyses of differential stress/inflammatory responses in mandibular lymph nodes and oropharyngeal tonsils of European wild boars naturally infected with Mycobacterium bovis.

Gene silencing of the tick protective antigens, Bm86, Bm91 and subolesin, in the one-host tick Boophilus microplus by RNA interference.

Comparison of the efficacy of enrofloxacin, imidocarb, and oxytetracycline for clearance of persistent Anaplasma marginale infections in cattle.

Transovarial silencing of the subolesin gene in three-host ixodid tick species after injection of replete females with subolesin dsRNA.

Differential expression of inflammatory and immune response genes in mesenteric lymph nodes of Iberian red deer (Cervus elaphus hispanicus) naturally infected with Mycobacterium bovis.

RNA interference for the study and genetic manipulation of ticks.

Comparison of the complement fixation test and competitive ELISA for serodiagnosis of Anaplasma marginale infection in experimentally infected steers.

A ten-year review of commercial vaccine performance for control of tick infestations on cattle.

Sp110 transcription is induced and required by Anaplasma phagocytophilum for infection of human promyelocytic cells.

Movement of Rhipicephalus sanguineus adults between co-housed dogs during active feeding.

Functional genomic studies of tick cells in response to infection with the cattle pathogen, Anaplasma marginale.

Experimental transmission of Anaplasma marginale by male Dermacentor reticulatus.

Expression of perilipin in human promyelocytic cells in response to Anaplasma phagocytophilum infection results in modified lipid metabolism.

Serologic and molecular characterization of tickborne pathogens in lions (Panthera leo) from the Fasano Safari Park, Italy.

Overview: Ticks as vectors of pathogens that cause disease in humans and animals.

Targeting the tick-pathogen interface for novel control strategies.

Advances toward understanding the molecular biology of the Anaplasma-tick interface.

Silencing expression of the defensin, varisin, in male Dermacentor variabilis by RNA interference results in reduced Anaplasma marginale infections.

Observations on Antricola ticks: small nymphs feed on mammalian hosts and have a salivary gland structure similar to ixodid ticks.

Differential expression of inflammatory and immune response genes in sheep infected with Anaplasma phagocytophilum.

Evidence of the role of tick subolesin in gene expression.

The impact of RNA interference of the subolesin and voraxin genes in male Amblyomma hebraeum (Acari: Ixodidae) on female engorgement and oviposition.

Inoculation of white-tailed deer (Odocoileus virginianus) with Ap-V1 Or NY-18 strains of Anaplasma phagocytophilum and microscopic demonstration of Ap-V1 In Ixodes scapularis adults that acquired infection from deer as nymphs.

Tick subolesin is an ortholog of the akirins described in insects and vertebrates.

Ultrastructural and fluorochromatic changes of Anaplasma marginale exposed to oxytetracycline, imidocarb and enrofloxacin in short-term erythrocyte cultures.

Differential expression of inflammatory and immune response genes in rams experimentally infected with a rough virulent strain of Brucella ovis.

Differential expression of the tick protective antigen subolesin in anaplasma marginale- and A. phagocytophilum-infected host cells.

Defining the role of subolesin in tick cell culture by use of RNA interference.

Gene expression profiles of European wild boar naturally infected with Mycobacterium bovis.

Transmission of Cytauxzoon felis to a domestic cat by Amblyomma americanum.

Conservation and immunogenicity of the mosquito ortholog of the tick-protective antigen, subolesin.

Genetic diversity of Anaplasma marginale in Argentina.

Characterization of possible correlates of protective response against Brucella ovis infection in rams immunized with the B. melitensis Rev 1 vaccine.

Silencing of genes involved in Anaplasma marginale-tick interactions affects the pathogen developmental cycle in Dermacentor variabilis.

Light and transmission electron microscopic characteristics of a novel Hepatozoon spp. in naturally infected cotton rats (Sigmodon hispidus).

Anaplasma phagocytophilum and Anaplasma marginale elicit different gene expression responses in cultured tick cells.

Phylogeographic analysis reveals association of tick-borne pathogen, Anaplasma marginale, MSP1a sequences with ecological traits affecting tick vector performance.

The natural history of Anaplasma marginale.

Functional genomics and evolution of tick-Anaplasma interactions and vaccine development.

Identification of protective antigens by RNA interference for control of the lone star tick, Amblyomma americanum.

Subolesin expression in response to pathogen infection in ticks.

Differential expression of genes in salivary glands of male Rhipicephalus (Boophilus)microplus in response to infection with Anaplasma marginale.

Characterization of Anaplasma phagocytophilum and A. ovis infection in a naturally infected sheep flock with poor health condition.

Characterization of pathogen-specific expression of host immune response genes in Anaplasma and Mycobacterium species infected ruminants.

Control of Rhipicephalus (Boophilus) microplus infestations by the combination of subolesin vaccination and tick autocidal control after subolesin gene knockdown in ticks fed on cattle.

The relevance of tick bites to the production of IgE antibodies to the mammalian oligosaccharide galactose-α-1,3-galactose.

Targeting arthropod subolesin/akirin for the development of a universal vaccine for control of vector infestations and pathogen transmission.

Expression of Heat Shock and Other Stress Response Proteins in Ticks and Cultured Tick Cells in Response to Anaplasma spp. Infection and Heat Shock.