Joseph L. DeRisi

DNA microarrays for malaria.

Mnd1p: an evolutionarily conserved protein required for meiotic recombination.

The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae.

Microarray-based detection and genotyping of viral pathogens.

Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray.

Characterization of a novel coronavirus associated with severe acute respiratory syndrome.

The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum.

Viral discovery and sequence recovery using DNA microarrays.

Parallel synthesis and antimalarial screening of a 4-aminoquinoline library.

The kinetochore is an enhancer of pericentric cohesin binding.

Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae.

Pernicious plans revealed: Plasmodium falciparum genome wide expression analysis.

Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae.

Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities.

Genome-wide identification of genes upregulated at the onset of gametocytogenesis in Plasmodium falciparum.

E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns.

Parallel synthesis of 9-aminoacridines and their evaluation against chloroquine-resistant Plasmodium falciparum.

Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae.

Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant.

Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains.

Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant.

Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise.

Incorporation of an intramolecular hydrogen-bonding motif in the side chain of 4-aminoquinolines enhances activity against drug-resistant P. falciparum.

Searching for new antimalarial therapeutics amongst known drugs.

Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum.

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult.

Rapid DNA mapping by fluorescent single molecule detection.

An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors.

Cis-acting determinants of asymmetric, cytoplasmic RNA transport.

Genome-wide diversity and selective pressure in the human rhinovirus.

Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray.

Whole-genome analysis of mRNA decay in Plasmodium falciparum reveals a global lengthening of mRNA half-life during the intra-erythrocytic development cycle.

Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity.

N-terminal processing of proteins exported by malaria parasites.

Utility of DNA microarrays for detection of viruses in acute respiratory tract infections in children.

Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: identification of a candidate etiologic agent.

Identification of cardioviruses related to Theiler's murine encephalomyelitis virus in human infections.

Experimental malaria infection triggers early expansion of natural killer cells.

The long march: a sample preparation technique that enhances contig length and coverage by high-throughput short-read sequencing.

The complete genome of klassevirus - a novel picornavirus in pediatric stool.

Experimental induction of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) inoculated with brain homogenates containing avian bornavirus 4.

Inhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamers.

Antiparasitic activities of novel, orally available fumagillin analogs.

An enhanced single base extension technique for the analysis of complex viral populations.

Analysis of naturally occurring avian bornavirus infection and transmission during an outbreak of proventricular dilatation disease among captive psittacine birds.

Improved methods for magnetic purification of malaria parasites and haemozoin.

VersaCount: customizable manual tally software for cell counting.

Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models.

Chemical genetics of Plasmodium falciparum.

Human enterovirus 109: a novel interspecies recombinant enterovirus isolated from a case of acute pediatric respiratory illness in Nicaragua.

Avian bornavirus is present in many tissues of psittacine birds with histopathologic evidence of proventricular dilatation disease.

Serological evidence of human klassevirus infection.

De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis.

HMMSplicer: a tool for efficient and sensitive discovery of known and novel splice junctions in RNA-Seq data.

Evaluation of Diarylureas for Activity Against Plasmodium falciparum.

RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts.

NK cells and immune "memory".

Transcriptome sequencing demonstrates that human papillomavirus is not active in cutaneous squamous cell carcinoma.

Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia.

Validation of a diagnostic microarray for human papillomavirus: coverage of 102 genotypes.

Synthesis and evaluation of 7-substituted 4-aminoquinoline analogues for antimalarial activity.

Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum.

Assemblathon 1: a competitive assessment of de novo short read assembly methods.

Optimization of propafenone analogues as antimalarial leads.

ReCombine: a suite of programs for detection and analysis of meiotic recombination in whole-genome datasets.

Plate-based transfection and culturing technique for genetic manipulation of Plasmodium falciparum.

The 3A protein from multiple picornaviruses utilizes the Golgi Adaptor Protein ACBD3 to Recruit PI4KIIIβ