S'identifier

Sarah Arrowsmith

Harris-Wellbeing Preterm Birth Research Centre,
Department of Cellular and Molecular Physiology,
Institute of Translational Medicine,
Harris-Wellbeing Preterm Birth Research Centre, Department of Cellular and Molecular Physiology, Institute of Translational Medicine

University of Liverpool

BIOGRAPHY

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PUBLICATIONS

Poor spontaneous and oxytocin-stimulated contractility in human myometrium from postdates pregnancies.

PloS one , 2012 | Pubmed ID: 22590608

What do we know about what happens to myometrial function as women age?

Journal of muscle research and cell motility Aug, 2012 | Pubmed ID: 22644420

A comparison of the contractile properties of myometrium from singleton and twin pregnancies.

PloS one , 2013 | Pubmed ID: 23671701

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.

Proceedings of the National Academy of Sciences of the United States of America Dec, 2013 | Pubmed ID: 24248349

Myometrial physiology--time to translate?

Experimental physiology Mar, 2014 | Pubmed ID: 24317408

Hypoxia-induced force increase (HIFI) is a novel mechanism underlying the strengthening of labor contractions, produced by hypoxic stresses.

Proceedings of the National Academy of Sciences of the United States of America Aug, 2015 | Pubmed ID: 26195731

Differing In Vitro Potencies of Tocolytics and Progesterone in Myometrium From Singleton and Twin Pregnancies.

Reproductive sciences (Thousand Oaks, Calif.) Jan, 2016 | Pubmed ID: 26239389

Ethnobotanical survey of Rinorea dentata (Violaceae) used in South-Western Nigerian ethnomedicine and detection of cyclotides.

Journal of ethnopharmacology Feb, 2016 | Pubmed ID: 26721222

The combination tocolytic effect of magnesium sulfate and an oxytocin receptor antagonist in myometrium from singleton and twin pregnancies.

American journal of obstetrics and gynecology Dec, 2016 | Pubmed ID: 27555315

Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide.

Scientific reports Feb, 2017 | Pubmed ID: 28145450

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.

Science signaling Dec, 2017 | Pubmed ID: 29208680

INSTITUTIONS

University of Liverpool

JOVE ARTICLES

Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development

Sarah Arrowsmith^*,1,

Peter Keov²,

Markus Muttenthaler^3,4,

Christian W. Gruber^*,2,5

¹Harris-Wellbeing Preterm Birth Research Centre, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool,

²School of Biomedical Sciences, The University of Queensland,

³Faculty of Chemistry, Institute of Biological Chemistry, University of Vienna,

⁴Institute for Molecular Bioscience, University of Queensland,

⁵Center for Physiology and Pharmacology, Medical University of Vienna

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