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School of Biomedical Sciences
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Biochemical and biophysical characterization of a novel plant protein disulfide isomerase.
Biopolymers , 2009 | Pubmed ID: 18985675
Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors.
Current pharmaceutical design , 2010 | Pubmed ID: 20687879
Discovery of defense- and neuropeptides in social ants by genome-mining.
PloS one , 2012 | Pubmed ID: 22448224
Exploring bioactive peptides from natural sources for oxytocin and vasopressin drug discovery.
Future medicinal chemistry Sep, 2012 | Pubmed ID: 23043476
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.
Natural product reports Nov, 2012 | Pubmed ID: 23165928
Cyclotides Suppress Human T-Lymphocyte Proliferation by an Interleukin 2-Dependent Mechanism.
PloS one , 2013 | Pubmed ID: 23840803
Physiology of invertebrate oxytocin and vasopressin neuropeptides.
Experimental physiology Jan, 2014 | Pubmed ID: 23955310
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2013 | Pubmed ID: 24248349
Immunosuppressive peptides and their therapeutic applications.
Drug discovery today May, 2014 | Pubmed ID: 24333193
Ribifolin, an orbitide from Jatropha ribifolia, and its potential antimalarial activity.
Journal of natural products Mar, 2015 | Pubmed ID: 25699574
Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum.
Journal of natural products May, 2015 | Pubmed ID: 25894999
Peptidomics of Circular Cysteine-Rich Plant Peptides: Analysis of the Diversity of Cyclotides from Viola tricolor by Transcriptome and Proteome Mining.
Journal of proteome research Nov, 2015 | Pubmed ID: 26399495
Ethnobotanical survey of Rinorea dentata (Violaceae) used in South-Western Nigerian ethnomedicine and detection of cyclotides.
Journal of ethnopharmacology Feb, 2016 | Pubmed ID: 26721222
MALDI TOF/TOF-Based Approach for the Identification of d- Amino Acids in Biologically Active Peptides and Proteins.
Journal of proteome research 05, 2016 | Pubmed ID: 26985971
Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2016 | Pubmed ID: 27035952
Global map of oxytocin/vasopressin-like neuropeptide signalling in insects.
Scientific reports Dec, 2016 | Pubmed ID: 27958372
Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide.
Scientific reports Feb, 2017 | Pubmed ID: 28145450
Cyclotides Isolated from an Ipecac Root Extract Antagonize the Corticotropin Releasing Factor Type 1 Receptor.
Frontiers in pharmacology , 2017 | Pubmed ID: 29033832
Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.
Science signaling Dec, 2017 | Pubmed ID: 29208680
The University of Queensland
Medical University of Vienna
Sarah Arrowsmith*,1,
Peter Keov2,
Markus Muttenthaler3,4,
Christian W. Gruber*,2,5
1Harris-Wellbeing Preterm Birth Research Centre, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool,
2School of Biomedical Sciences, The University of Queensland,
3Faculty of Chemistry, Institute of Biological Chemistry, University of Vienna,
4Institute for Molecular Bioscience, University of Queensland,
5Center for Physiology and Pharmacology, Medical University of Vienna
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