S'identifier

Yun Huang

Centre for Epigenetics and Disease Prevention,
Department of Molecular and Cellular Medicine,
Institute of Biosciences and Technology,
College of Medicine,
Centre for Epigenetics and Disease Prevention, Department of Molecular and Cellular Medicine, Institute of Biosciences and Technology, College of Medicine

Texas A&M University

BIOGRAPHY

Yunlong Huang is presently a PhD candidate at Tsinghua University, Beijing, China. He has been trained in Linguistics since undergraduate and is now majoring in Linguistics and Applied Linguistics.

His research interests include the cognitive mechanism and neural basis of sentence comprehension, and computational cognitive modeling of language understanding. Presently, he is interested in the brain’s processing of both semantic and syntactic information, their interplay with each other and with some more general cognitive systems such as memory in Chinese sentence comprehension, and establishing computational cognitive models of Chinese semantic and syntactic information processing. He mainly uses ERP and fMRI techniques to explore the language information processing of normal human participants.

PUBLICATIONS

Connections between TET proteins and aberrant DNA modification in cancer.

Trends in genetics : TIG Oct, 2014 | Pubmed ID: 25132561

Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca²⁺ influx.

Nature cell biology Oct, 2015 | Pubmed ID: 26322679

Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.

eLife Dec, 2015 | Pubmed ID: 26646180

A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways.

Genome biology Mar, 2016 | Pubmed ID: 26975309

Optogenetic toolkit for precise control of calcium signaling.

Cell calcium Jun, 2017 | Pubmed ID: 28104276

Engineered Split-TET2 Enzyme for Inducible Epigenetic Remodeling.

Journal of the American Chemical Society Apr, 2017 | Pubmed ID: 28294608

Elevated Adenosine Induces Placental DNA Hypomethylation Independent of A2B Receptor Signaling in Preeclampsia.

Hypertension (Dallas, Tex. : 1979) Jul, 2017 | Pubmed ID: 28507174

Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.

The Journal of clinical investigation Aug, 2017 | Pubmed ID: 28691928

The STIM-Orai Pathway: Light-Operated Ca2+ Entry Through Engineered CRAC Channels.

Advances in experimental medicine and biology , 2017 | Pubmed ID: 28900912

Optical control of membrane tethering and interorganellar communication at nanoscales.

Chemical science Aug, 2017 | Pubmed ID: 28959426

CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation.

Nature communications Oct, 2017 | Pubmed ID: 29079782

Bioluminescence probe for γ-glutamyl transpeptidase detection in vivo.

Bioorganic & medicinal chemistry Nov, 2017 | Pubmed ID: 29174510

Prolonged bioluminescence imaging in living cells and mice using novel pro-substrates for Renilla luciferase.

Organic & biomolecular chemistry Nov, 2017 | Pubmed ID: 29177293

INSTITUTIONS

Texas A&M University

JOVE ARTICLES

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling

Minjung Lee¹,

Yubin Zhou²,

Yun Huang¹

¹Centre for Epigenetics and Disease Prevention, Department of Molecular and Cellular Medicine, Institute of Biosciences and Technology, College of Medicine, Texas A&M University,

²Centre for Translational Cancer Research, Department of Medical Physiology, Institute of Biosciences and Technology, College of Medicine, Texas A&M University

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