S'identifier

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling

6.5K Views

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08:34 min

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December 18th, 2017

DOI :

10.3791/56858-v

December 18th, 2017

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6,521 Views

Minjung Lee¹, Yubin Zhou², Yun Huang¹

¹Centre for Epigenetics and Disease Prevention, Department of Molecular and Cellular Medicine, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, ²Centre for Translational Cancer Research, Department of Medical Physiology, Institute of Biosciences and Technology, College of Medicine, Texas A&M University

Chapitres

Transcription

Résumé

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Split TET2

CiDER

DNA Hydroxymethylation

Epigenetic Remodeling

Chemical Induction

Rapamycin

Flow Cytometry

5 hydroxymethylcytosine 5hmC

Genomic DNA

Slot Blot Analysis

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