Jean-Philippe Julien

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.

Origins of a Vaccine-Induced, Human Anti-HIV-1 Antibody.

Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens.

EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis.

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.

Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming.

Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

Molecular basis of human CD22 function and therapeutic targeting.

Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.

Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.

Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments.

Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11.

Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies.

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.