Randal Halfmann

Chaperone-dependent amyloid assembly protects cells from prion toxicity.

A systematic survey identifies prions and illuminates sequence features of prionogenic proteins.

Prions, protein homeostasis, and phenotypic diversity.

Biochemical, cell biological, and genetic assays to analyze amyloid and prion aggregation in yeast.

Epigenetics in the extreme: prions and the inheritance of environmentally acquired traits.

A method for probing the mutational landscape of amyloid structure.

Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins.

Prions are a common mechanism for phenotypic inheritance in wild yeasts.

A glass menagerie of low complexity sequences.

A self-perpetuating repressive state of a viral replication protein blocks superinfection by the same virus.

Quantifying Nucleation In Vivo Reveals the Physical Basis of Prion-like Phase Behavior.

Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation.