Giampietro Schiavo

The journey of tetanus and botulinum neurotoxins in neurons.

Phosphatidylinositol 3-kinase C2alpha is essential for ATP-dependent priming of neurosecretory granule exocytosis.

Large-scale pathways-based association study in amyotrophic lateral sclerosis.

Deficits in axonal transport precede ALS symptoms in vivo.

A motor-driven mechanism for cell-length sensing.

Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane.

Synthetic self-assembling clostridial chimera for modulation of sensory functions.

Cytoplasmic dynein heavy chain: the servant of many masters.

Signalling endosomes in axonal transport: travel updates on the molecular highway.

TiME for TMEM106B.

Rabies virus envelope glycoprotein targets lentiviral vectors to the axonal retrograde pathway in motor neurons.

DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy.

siRNA screen of ES cell-derived motor neurons identifies novel regulators of tetanus toxin and neurotrophin receptor trafficking.

Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors.

Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease.

Tetanus toxin entry. Nidogens are therapeutic targets for the prevention of tetanus.

Novel Kidins220/ARMS Splice Isoforms: Potential Specific Regulators of Neuronal and Cardiovascular Development.

Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model.

Regulation of Axonal Transport by Protein Kinases.

In vivo imaging of axonal transport in murine motor and sensory neurons.

Mon1-Ccz1 activates Rab7 only on late endosomes and dissociates from the lysosome in mammalian cells.

Analysis of Signaling Endosome Composition and Dynamics Using SILAC in Embryonic Stem Cell-Derived Neurons.

A simple, step-by-step dissection protocol for the rapid isolation of mouse dorsal root ganglia.

Targeting protein homeostasis in sporadic inclusion body myositis.

The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1.

Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity.

Neuronal retrograde transport of Borna disease virus occurs in signalling endosomes.

Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system.

Methodological advances in imaging intravital axonal transport.

Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by mutations.

Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis.

The travel diaries of tetanus and botulinum neurotoxins.

A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models.

Compartmentalized Signaling in Neurons: From Cell Biology to Neuroscience.

Functional imaging in microfluidic chambers reveals sensory neuron sensitivity is differentially regulated between neuronal regions.

Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS.

The many disguises of the signalling endosome.

UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy.

Retrograde transport of Akt by a neuronal Rab5-APPL1 endosome.

Toxins 2017 conference in Madrid.

Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.

Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition.

Differential regulation of Kidins220 isoforms in Huntington's disease.

Axonal transport and neurological disease.

TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering.

The evolution of the axonal transport toolkit.

Travelling Together: A Unifying Pathomechanism for ALS.

IGF1R regulates retrograde axonal transport of signalling endosomes in motor neurons.

PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors.

DYNLRB1 is essential for dynein mediated transport and neuronal survival.

Duplication of clostridial binding domains for enhanced macromolecular delivery into neurons.

Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy.

Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes.

FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.

In Vivo Imaging of Anterograde and Retrograde Axonal Transport in Rodent Peripheral Nerves.

Morphological variability is greater at developing than mature mouse neuromuscular junctions.

A video protocol for rapid dissection of mouse dorsal root ganglia from defined spinal levels.

Developmental demands contribute to early neuromuscular degeneration in CMT2D mice.

Knockin' on heaven's door: Molecular mechanisms of neuronal tau uptake.

Altered Sensory Neuron Development in CMT2D Mice Is Site-Specific and Linked to Increased GlyRS Levels.

Potential human transmission of amyloid β pathology: surveillance and risks.

Walking the line: mechanisms underlying directional mRNA transport and localisation in neurons and beyond.

Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation.

NMJ-Analyser identifies subtle early changes in mouse models of neuromuscular disease.

Dissection, in vivo imaging and analysis of the mouse epitrochleoanconeus muscle.

FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.

Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.