James N. Sleigh

In vivo imaging of axonal transport in murine motor and sensory neurons.

Vascular Defects and Spinal Cord Hypoxia in Spinal Muscular Atrophy.

A simple, step-by-step dissection protocol for the rapid isolation of mouse dorsal root ganglia.

Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy.

Methodological advances in imaging intravital axonal transport.

Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by mutations.

Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis.

Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis.

Aligned electrospun fibers for neural patterning.

Antisense oligonucleotides and other genetic therapies made simple.

Plexin-Semaphorin Signaling Modifies Neuromuscular Defects in a Model of Peripheral Neuropathy.

UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy.

Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition.

Axonal transport and neurological disease.

Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.

The evolution of the axonal transport toolkit.

Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy.

Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes.

In Vivo Imaging of Anterograde and Retrograde Axonal Transport in Rodent Peripheral Nerves.

Morphological variability is greater at developing than mature mouse neuromuscular junctions.

A video protocol for rapid dissection of mouse dorsal root ganglia from defined spinal levels.

Developmental demands contribute to early neuromuscular degeneration in CMT2D mice.

Intramuscular Delivery of Gene Therapy for Targeting the Nervous System.

Altered Sensory Neuron Development in CMT2D Mice Is Site-Specific and Linked to Increased GlyRS Levels.

NMJ-Analyser identifies subtle early changes in mouse models of neuromuscular disease.

Dissection, in vivo imaging and analysis of the mouse epitrochleoanconeus muscle.