Simon Melov has not added Biography.
If you are Simon Melov and would like to personalize this page please email our Author Liaison for assistance.
'...and C is for Clioquinol' - the AbetaCs of Alzheimer's disease.
Trends in neurosciences Mar, 2002 | Pubmed ID: 11852134
Applied proteomics: mitochondrial proteins and effect on function.
Circulation research Mar, 2002 | Pubmed ID: 11884366
Therapeutics against mitochondrial oxidative stress in animal models of aging.
Annals of the New York Academy of Sciences Apr, 2002 | Pubmed ID: 11976207
Animal models of oxidative stress, aging, and therapeutic antioxidant interventions.
The international journal of biochemistry & cell biology Nov, 2002 | Pubmed ID: 12200034
Microarray workshop on aging.
Mechanisms of ageing and development Jan, 2003 | Pubmed ID: 12618016
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts.
Nature cell biology Aug, 2003 | Pubmed ID: 12855956
Oxidative stress and aging: beyond correlation.
Aging cell Dec, 2002 | Pubmed ID: 12882341
Spotlight on nematode mitochondria in RNAi mega-screen.
Science of aging knowledge environment : SAGE KE Nov, 2002 | Pubmed ID: 14603016
Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice.
Journal of neurochemistry Feb, 2004 | Pubmed ID: 14720215
Microarray analysis of gene expression with age in individual nematodes.
Aging cell Jun, 2004 | Pubmed ID: 15153179
Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples.
Electrophoresis Aug, 2004 | Pubmed ID: 15300776
Modeling mitochondrial function in aging neurons.
Trends in neurosciences Oct, 2004 | Pubmed ID: 15374671
Proteomic analysis of mitochondrial proteins.
International review of neurobiology , 2004 | Pubmed ID: 15482810
Microarrays as a tool to investigate the biology of aging: a retrospective and a look to the future.
Science of aging knowledge environment : SAGE KE Oct, 2004 | Pubmed ID: 15498758
Mice transgenic for Alzheimer disease beta-amyloid develop lens cataracts that are rescued by antioxidant treatment.
Free radical biology & medicine Jan, 2005 | Pubmed ID: 15607908
Pharmacogenomic profiling of an oxidative stress-mediated spongiform encephalopathy.
Free radical biology & medicine Jul, 2005 | Pubmed ID: 15964507
Hyperplasia, reduced E-cadherin expression, and developmental arrest in mammary glands oxidatively stressed by loss of mitochondrial superoxide dismutase.
Breast (Edinburgh, Scotland) Aug, 2005 | Pubmed ID: 16085231
Gene expression profiling in mitochondrial disease: assessment of microarray accuracy by high-throughput Q-PCR.
Mitochondrion Sep, 2004 | Pubmed ID: 16120406
Alzheimer disease beta-amyloid activity mimics cholesterol oxidase.
The Journal of clinical investigation Sep, 2005 | Pubmed ID: 16127459
Biomarker discovery and analysis platform: application to Alzheimer's disease.
BioTechniques Oct, 2005 | Pubmed ID: 16235574
Science fact and the SENS agenda. What can we reasonably expect from ageing research?
EMBO reports Nov, 2005 | Pubmed ID: 16264422
Mitochondrial reactive oxygen species in mice lacking superoxide dismutase 2: attenuation via antioxidant treatment.
The Journal of biological chemistry Feb, 2006 | Pubmed ID: 16326710
Pol II-expressed shRNA knocks down Sod2 gene expression and causes phenotypes of the gene knockout in mice.
PLoS genetics Jan, 2006 | Pubmed ID: 16450009
Nigrostriatal dopaminergic neurodegeneration in the weaver mouse is mediated via neuroinflammation and alleviated by minocycline administration.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2006 | Pubmed ID: 17093086
Dramatic age-related changes in nuclear and genome copy number in the nematode Caenorhabditis elegans.
Aging cell Apr, 2007 | Pubmed ID: 17286610
Resistance exercise reverses aging in human skeletal muscle.
PloS one , 2007 | Pubmed ID: 17520024
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
PloS one , 2007 | Pubmed ID: 17579710
Global and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementation.
Physiological genomics Jan, 2008 | Pubmed ID: 17957000
Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans.
The Journal of biological chemistry Jan, 2008 | Pubmed ID: 17959600
Gene expression changes associated with aging in C. elegans.
WormBook : the online review of C. elegans biology , 2007 | Pubmed ID: 18050504
Age-related behaviors have distinct transcriptional profiles in Caenorhabditis elegans.
Aging cell Dec, 2008 | Pubmed ID: 18778409
Increase in mitochondrial biogenesis, oxidative stress, and glycolysis in murine lymphomas.
Free radical biology & medicine Feb, 2009 | Pubmed ID: 19038329
A human protein interaction network shows conservation of aging processes between human and invertebrate species.
PLoS genetics Mar, 2009 | Pubmed ID: 19293945
Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women.
PloS one , 2009 | Pubmed ID: 19654872
Eccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways not affected by hormone changes.
PloS one , 2010 | Pubmed ID: 20502695
Insulin-like signaling determines survival during stress via posttranscriptional mechanisms in C. elegans.
Cell metabolism Sep, 2010 | Pubmed ID: 20816092
Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.
Free radical biology & medicine Apr, 2011 | Pubmed ID: 21215798
The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation.
Experimental gerontology Jun, 2011 | Pubmed ID: 21296648
Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2011 | Pubmed ID: 21368114
Loss of intestinal nuclei and intestinal integrity in aging C. elegans.
Aging cell Aug, 2011 | Pubmed ID: 21501374
Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans.
Cell metabolism Jul, 2011 | Pubmed ID: 21723504
Cellular senescence: a link between cancer and age-related degenerative disease?
Seminars in cancer biology Dec, 2011 | Pubmed ID: 21925603
On the programmed/non-programmed nature of ageing within the life history.
Current biology : CB Sep, 2011 | Pubmed ID: 21959160
Human embryonic stem cells express elevated levels of multiple pro-apoptotic BCL-2 family members.
PloS one , 2011 | Pubmed ID: 22174832
Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin.
Aging Jan, 2012 | Pubmed ID: 22278880
Massage therapy attenuates inflammatory signaling after exercise-induced muscle damage.
Science translational medicine Feb, 2012 | Pubmed ID: 22301554