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Science for Life Laboratory,
Department of Oncology-Pathology,
Science for Life Laboratory, Department of Oncology-Pathology
Sean G. Rudd has not added Biography.
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PrimPol-A new polymerase on the block.
Molecular & cellular oncology Apr-Jun, 2014 | Pubmed ID: 27308331
Pathways controlling dNTP pools to maintain genome stability.
DNA repair 08, 2016 | Pubmed ID: 27311542
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
Nature medicine Feb, 2017 | Pubmed ID: 28067901
SAMHD1 is a barrier to antimetabolite-based cancer therapies.
Molecular & cellular oncology , 2017 | Pubmed ID: 28401188
SAMHD1 protects cancer cells from various nucleoside-based antimetabolites.
Cell cycle (Georgetown, Tex.) Jun, 2017 | Pubmed ID: 28436707
With me or against me: Tumor suppressor and drug resistance activities of SAMHD1.
Experimental hematology 08, 2017 | Pubmed ID: 28502830
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Nature communications 01, 2018 | Pubmed ID: 29343827
Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism.
Cancers Jul, 2018 | Pubmed ID: 30041457
Low-level expression of SAMHD1 in acute myeloid leukemia (AML) blasts correlates with improved outcome upon consolidation chemotherapy with high-dose cytarabine-based regimens.
Blood cancer journal 10, 2018 | Pubmed ID: 30341277
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Nature communications Nov, 2019 | Pubmed ID: 31676755
Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy.
EMBO molecular medicine 03, 2020 | Pubmed ID: 31950591
Cell Cycle Profiling Reveals Protein Oscillation, Phosphorylation, and Localization Dynamics.
Molecular & cellular proteomics : MCP 04, 2020 | Pubmed ID: 32051232
MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG.
Cancer research 09, 2020 | Pubmed ID: 32312836
Development of a chemical probe against NUDT15.
Nature chemical biology 10, 2020 | Pubmed ID: 32690945
Drug synergy scoring using minimal dose response matrices.
BMC research notes Jan, 2021 | Pubmed ID: 33468238
Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity.
The Journal of biological chemistry Mar, 2021 | Pubmed ID: 33753169
Karolinska Institutet
Miriam Yagüe-Capilla1,
Sean G. Rudd1
1Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet
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