Nicholas School of the Environment
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Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): heritability of altered expression and relationship to survival in contaminated sediments.
Toxicological sciences : an official journal of the Society of Toxicology Jul, 2002 | Pubmed ID: 12075112
Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories.
Environmental toxicology and chemistry Oct, 2003 | Pubmed ID: 14551997
Antioxidant defenses in killifish (Fundulus heteroclitus) exposed to contaminated sediments and model prooxidants: short-term and heritable responses.
Aquatic toxicology (Amsterdam, Netherlands) Dec, 2003 | Pubmed ID: 14568353
Differential display of hepatic mRNA from killifish (Fundulus heteroclitus) inhabiting a Superfund estuary.
Aquatic toxicology (Amsterdam, Netherlands) Jul, 2005 | Pubmed ID: 15916819
Analysis of CpG methylation in the killifish CYP1A promoter.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP Aug, 2005 | Pubmed ID: 16257583
Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics.
Comparative biochemistry and physiology. Part D, Genomics & proteomics Dec, 2007 | Pubmed ID: 18071578
Nonadditive effects of PAHs on Early Vertebrate Development: mechanisms and implications for risk assessment.
Toxicological sciences : an official journal of the Society of Toxicology Sep, 2008 | Pubmed ID: 18156145
Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology.
Toxicological sciences : an official journal of the Society of Toxicology Nov, 2008 | Pubmed ID: 18566021
The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP Mar, 2009 | Pubmed ID: 18706522
UV disinfection of adenoviruses: molecular indications of DNA damage efficiency.
Applied and environmental microbiology Jan, 2009 | Pubmed ID: 18978087
Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure.
Mutation research Jan, 2010 | Pubmed ID: 19879883
QPCR: a tool for analysis of mitochondrial and nuclear DNA damage in ecotoxicology.
Ecotoxicology (London, England) Apr, 2010 | Pubmed ID: 20049526
Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology.
PLoS genetics Jan, 2010 | Pubmed ID: 20090835
The QPCR assay for analysis of mitochondrial DNA damage, repair, and relative copy number.
Methods (San Diego, Calif.) Aug, 2010 | Pubmed ID: 20123023
Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity.
PloS one May, 2010 | Pubmed ID: 20463971
Comparative biological effects and potency of 17α- and 17β-estradiol in fathead minnows.
Aquatic toxicology (Amsterdam, Netherlands) Oct, 2010 | Pubmed ID: 20692052
Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans.
Aquatic toxicology (Amsterdam, Netherlands) Oct, 2010 | Pubmed ID: 20708279
Caenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B1 but not benzo[a]pyrene in vivo.
Toxicological sciences : an official journal of the Society of Toxicology Dec, 2010 | Pubmed ID: 20864627
Mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans.
Environmental science & technology Jan, 2012 | Pubmed ID: 22148238
Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers.
The Journal of biological chemistry Mar, 2012 | Pubmed ID: 22194617
Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans.
Nucleic acids research Sep, 2012 | Pubmed ID: 22718972
Mitochondrial DNA-depleted A549 cells are resistant to bleomycin.
American journal of physiology. Lung cellular and molecular physiology Sep, 2012 | Pubmed ID: 22773697
Involvement of autophagy and mitochondrial dynamics in determining the fate and effects of irreparable mitochondrial DNA damage.
Autophagy Dec, 2012 | Pubmed ID: 22929123
Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22941600
In vivo repair of alkylating and oxidative DNA damage in the mitochondrial and nuclear genomes of wild-type and glycosylase-deficient Caenorhabditis elegans.
DNA repair Nov, 2012 | Pubmed ID: 22959841
UVC-induced mitochondrial degradation via autophagy correlates with mtDNA damage removal in primary human fibroblasts.
Journal of biochemical and molecular toxicology Jan, 2013 | Pubmed ID: 23132756
Effects of early life exposure to ultraviolet C radiation on mitochondrial DNA content, transcription, ATP production, and oxygen consumption in developing Caenorhabditis elegans.
BMC pharmacology & toxicology Feb, 2013 | Pubmed ID: 23374645
A call for fuller reporting of toxicity test data.
Integrated environmental assessment and management Apr, 2013 | Pubmed ID: 23529809
Mitochondria as a Target of Environmental Toxicants.
Toxicological sciences : an official journal of the Society of Toxicology May, 2013 | Pubmed ID: 23629515
The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces mitochondrial and nuclear DNA damage in Caenorhabditis elegans.
Environmental and molecular mutagenesis Jan, 2014 | Pubmed ID: 24014178
Effects of mutations in mitochondrial dynamics-related genes on the mitochondrial response to ultraviolet C radiation in developing Caenorhabditis elegans.
Worm Jan, 2013 | Pubmed ID: 24058863
Assessing different mechanisms of toxicity in mountaintop removal/valley fill coal mining-affected watershed samples using Caenorhabditis elegans.
PloS one , 2013 | Pubmed ID: 24066176
Sulfidation of Silver Nanoparticles: Natural antidote to their toxicity.
Environmental science & technology Nov, 2013 | Pubmed ID: 24180218
Silver nanoparticle behavior, uptake, and toxicity in Caenorhabditis elegans: effects of natural organic matter.
Environmental science & technology Mar, 2014 | Pubmed ID: 24568198
Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans.
Experimental gerontology Aug, 2014 | Pubmed ID: 24704715
Comparative toxicity of silver nanoparticles on oxidative stress and DNA damage in the nematode, Caenorhabditis elegans.
Chemosphere Aug, 2014 | Pubmed ID: 24726479
Developmental toxicity and DNA damage from exposure to parking lot runoff retention pond samples in the Japanese medaka (Oryzias latipes).
Marine environmental research Aug, 2014 | Pubmed ID: 24816191
DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis.
Nature cell biology Aug, 2014 | Pubmed ID: 25064737
Mitochondria, energetics, epigenetics, and cellular responses to stress.
Environmental health perspectives Dec, 2014 | Pubmed ID: 25127496
PCR based determination of mitochondrial DNA copy number in multiple species.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 25308485
Silver nanoparticle toxicity to Atlantic killifish (Fundulus heteroclitus) and Caenorhabditis elegans: a comparison of mesocosm, microcosm, and conventional laboratory studies.
Environmental toxicology and chemistry Feb, 2015 | Pubmed ID: 25393776
AHR2-Mediated transcriptomic responses underlying the synergistic cardiac developmental toxicity of PAHs.
Toxicological sciences : an official journal of the Society of Toxicology Feb, 2015 | Pubmed ID: 25412620
Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans.
PloS one , 2014 | Pubmed ID: 25486066
Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes.
PloS one , 2015 | Pubmed ID: 26106885
Reducing Environmental Toxicity of Silver Nanoparticles through Shape Control.
Environmental science & technology Aug, 2015 | Pubmed ID: 26146787
Caenorhabditis elegans as a Model for Toxic Effects of Nanoparticles: Lethality, Growth, and Reproduction.
Current protocols in toxicology Nov, 2015 | Pubmed ID: 26523472
Seahorse Xfe 24 Extracellular Flux Analyzer-Based Analysis of Cellular Respiration in Caenorhabditis elegans.
Current protocols in toxicology Nov, 2015 | Pubmed ID: 26523474
Intracellular trafficking pathways in silver nanoparticle uptake and toxicity in Caenorhabditis elegans.
Nanotoxicology 09, 2016 | Pubmed ID: 26559224
Mitochondrial DNA damage induced autophagy, cell death, and disease.
Frontiers in bioscience (Landmark edition) Jan, 2016 | Pubmed ID: 26709760
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy Jan, 2016 | Pubmed ID: 26799652
PCR-Based Analysis of Mitochondrial DNA Copy Number, Mitochondrial DNA Damage, and Nuclear DNA Damage.
Current protocols in toxicology Feb, 2016 | Pubmed ID: 26828332
Antagonistic Growth Effects of Mercury and Selenium in Caenorhabditis elegans Are Chemical-Species-Dependent and Do Not Depend on Internal Hg/Se Ratios.
Environmental science & technology Mar, 2016 | Pubmed ID: 26938845
From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans.
Toxicological sciences : an official journal of the Society of Toxicology 08, 2016 | Pubmed ID: 27208080
Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest.
Redox biology 10, 2016 | Pubmed ID: 27479053
In Vivo Determination of Mitochondrial Function Using Luciferase-Expressing Caenorhabditis elegans: Contribution of Oxidative Phosphorylation, Glycolysis, and Fatty Acid Oxidation to Toxicant-Induced Dysfunction.
Current protocols in toxicology 08, 2016 | Pubmed ID: 27479364
Effects of reduced mitochondrial DNA content on secondary mitochondrial toxicant exposure in Caenorhabditis elegans.
Mitochondrion 09, 2016 | Pubmed ID: 27566481
Biogas Stoves Reduce Firewood Use, Household Air Pollution, and Hospital Visits in Odisha, India.
Environmental science & technology 01, 2017 | Pubmed ID: 27785914
Effects of methyl and inorganic mercury exposure on genome homeostasis and mitochondrial function in Caenorhabditis elegans.
DNA repair 04, 2017 | Pubmed ID: 28242054
Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds among recently pregnant rural Guatemalan women cooking and heating with solid fuels.
International journal of hygiene and environmental health 06, 2017 | Pubmed ID: 28320639
Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability.
Toxicology 07, 2017 | Pubmed ID: 28602540
Sources, mechanisms, and consequences of chemical-induced mitochondrial toxicity.
Toxicology 11, 2017 | Pubmed ID: 28627407
Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like.
Environmental toxicology and pharmacology Sep, 2017 | Pubmed ID: 28728133
Mitochondrial fusion, fission, and mitochondrial toxicity.
Toxicology 11, 2017 | Pubmed ID: 28789970
Role of mitochondrial DNA damage and dysfunction in veterans with Gulf War Illness.
PloS one , 2017 | Pubmed ID: 28910366
Toxicological Implications of Mitochondrial Localization of CYP2E1.
Toxicology research , 2017 | Pubmed ID: 28989700
Materials and toxicological approaches to study metal and metal-oxide nanoparticles in the model organism .
Materials horizons Sep, 2017 | Pubmed ID: 29057078
The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells.
Toxicology 01, 2018 | Pubmed ID: 29127035
Mitochondrial Toxicity.
Toxicological sciences : an official journal of the Society of Toxicology 03, 2018 | Pubmed ID: 29340618
Swimming Exercise and Transient Food Deprivation in Caenorhabditis elegans Promote Mitochondrial Maintenance and Protect Against Chemical-Induced Mitotoxicity.
Scientific reports 05, 2018 | Pubmed ID: 29844465
Newly Revised Quantitative PCR-Based Assay for Mitochondrial and Nuclear DNA Damage.
Current protocols in toxicology 05, 2018 | Pubmed ID: 30040241
Caenorhabditis elegans as an emerging model system in environmental epigenetics.
Environmental and molecular mutagenesis 08, 2018 | Pubmed ID: 30091255
Nonselective autophagy reduces mitochondrial content during starvation in Caenorhabditis elegans.
American journal of physiology. Cell physiology 12, 2018 | Pubmed ID: 30133321
Predictors of mitochondrial DNA copy number and damage in a mercury-exposed rural Peruvian population near artisanal and small-scale gold mining: An exploratory study.
Environmental and molecular mutagenesis 03, 2019 | Pubmed ID: 30289587
Blinded Visual Scoring of Images Using the Freely-available Software Blinder.
Bio-protocol Dec, 2018 | Pubmed ID: 30761327
Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans.
Lab on a chip 03, 2019 | Pubmed ID: 30768117
Linking Mitochondrial Dysfunction to Organismal and Population Health in the Context of Environmental Pollutants: Progress and Considerations for Mitochondrial Adverse Outcome Pathways.
Environmental toxicology and chemistry 08, 2019 | Pubmed ID: 31034624
MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa.
European journal of cell biology Dec, 2019 | Pubmed ID: 31138438
Open source acoustofluidics.
Lab on a chip 07, 2019 | Pubmed ID: 31240285
Genetic Defects in Mitochondrial Dynamics in Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration.
International journal of molecular sciences Jun, 2019 | Pubmed ID: 31261893
Mitochondria as a target of organophosphate and carbamate pesticides: Revisiting common mechanisms of action with new approach methodologies.
Reproductive toxicology (Elmsford, N.Y.) 10, 2019 | Pubmed ID: 31315019
Strengths and limitations of morphological and behavioral analyses in detecting dopaminergic deficiency in Caenorhabditis elegans.
Neurotoxicology 09, 2019 | Pubmed ID: 31323240
Mitochondrial bioenergetic changes during development as an indicator of health-span.
Aging 08, 2019 | Pubmed ID: 31454791
Caveats to the use of MTT, neutral red, Hoechst and Resazurin to measure silver nanoparticle cytotoxicity.
Chemico-biological interactions Jan, 2020 | Pubmed ID: 31669321
Swim exercise in extends neuromuscular and gut healthspan, enhances learning ability, and protects against neurodegeneration.
Proceedings of the National Academy of Sciences of the United States of America 11, 2019 | Pubmed ID: 31685639
Effects of Immunosuppressive Medications on Mitochondrial Function.
The Journal of surgical research 05, 2020 | Pubmed ID: 31918330
Fluorescence-based sorting of Caenorhabditis elegans via acoustofluidics.
Lab on a chip 05, 2020 | Pubmed ID: 32292982
Resveratrol Protects Against Hydroquinone-Induced Oxidative Threat in Retinal Pigment Epithelial Cells.
Investigative ophthalmology & visual science 04, 2020 | Pubmed ID: 32334435
Zebrafish CYP1A expression in transgenic Caenorhabditis elegans protects from exposures to benzo[a]pyrene and a complex polycyclic aromatic hydrocarbon mixture.
Toxicology 07, 2020 | Pubmed ID: 32360973
strain sensitivity to sodium arsenite exposure is varied based on age and outcome measured.
microPublication biology Oct, 2019 | Pubmed ID: 32550437
Risuteganib Protects against Hydroquinone-induced Injury in Human RPE Cells.
Investigative ophthalmology & visual science 08, 2020 | Pubmed ID: 32818234
Evaluation of Peruvian Government Interventions to Reduce Childhood Anemia.
Annals of global health 08, 2020 | Pubmed ID: 32864350
Multiple metabolic changes mediate the response of Caenorhabditis elegans to the complex I inhibitor rotenone.
Toxicology 01, 2021 | Pubmed ID: 33188857
Xenobiotic metabolism and transport in .
Journal of toxicology and environmental health. Part B, Critical reviews Feb, 2021 | Pubmed ID: 33616007
Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans.
Redox biology 07, 2021 | Pubmed ID: 33993056
PCR-Based Determination of Mitochondrial DNA Copy Number in Multiple Species.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 34096001
Lack of Detectable Direct Effects of Silver and Silver Nanoparticles on Mitochondria in Mouse Hepatocytes.
Environmental science & technology Aug, 2021 | Pubmed ID: 34346225
Direct comparisons of bisulfite pyrosequencing versus targeted bisulfite sequencing.
microPublication biology , 2021 | Pubmed ID: 34423283
Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells.
Frontiers in immunology , 2021 | Pubmed ID: 34712241
Mitochondrial DNA Mutagenesis: Feature of and Biomarker for Environmental Exposures and Aging.
Current environmental health reports Nov, 2021 | Pubmed ID: 34761353