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Harrington Laboratory for Molecular Orthopedics,
Department of Orthopedic Surgery,
Harrington Laboratory for Molecular Orthopedics, Department of Orthopedic Surgery
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Transcription factor Nfat1 deficiency causes osteoarthritis through dysfunction of adult articular chondrocytes.
The Journal of pathology Oct, 2009 | Pubmed ID: 19526482
Nfat1 regulates adult articular chondrocyte function through its age-dependent expression mediated by epigenetic histone methylation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Aug, 2011 | Pubmed ID: 21452283
Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage.
The international journal of biochemistry & cell biology Mar, 2016 | Pubmed ID: 26806292
Epigenetically mediated spontaneous reduction of NFAT1 expression causes imbalanced metabolic activities of articular chondrocytes in aged mice.
Osteoarthritis and cartilage 07, 2016 | Pubmed ID: 26903200
Harnessing the Noncovalent Interactions of DNA Backbone with 2D Silicate Nanodisks To Fabricate Injectable Therapeutic Hydrogels.
ACS nano 10, 2018 | Pubmed ID: 30189128
Spontaneous Facet Joint Osteoarthritis in NFAT1-Mutant Mice: Age-Dependent Histopathologic Characteristics and Molecular Mechanisms.
The Journal of bone and joint surgery. American volume Feb, 2022 | Pubmed ID: 35167509
University of Kansas Medical Center
Xiangliang Liu*,1,
Michael A. Pitner*,1,
Patrick P. Baki1,
Qinghua Lu1,
John P. Schroeppel2,
Jinxi Wang1,3
1Harrington Laboratory for Molecular Orthopedics, Department of Orthopedic Surgery, University of Kansas Medical Center,
2Division of Sports Medicine, Department of Orthopedic Surgery, University of Kansas Medical Center,
3Department of Biochemistry & Molecular Biology, University of Kansas Medical Center
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