Department of Neurosurgery,
Marlene and Stewart Greenebaum Comprehensive Cancer Center
Graeme F. Woodworth has not added Biography.
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Histopathological correlates with survival in reoperated glioblastomas.
Journal of neuro-oncology Jul, 2013 | Pubmed ID: 23666202
Surgical outcomes using a medial-to-lateral endonasal endoscopic approach to pituitary adenomas invading the cavernous sinus.
Journal of neurosurgery May, 2014 | Pubmed ID: 24527820
Emerging insights into barriers to effective brain tumor therapeutics.
Frontiers in oncology , 2014 | Pubmed ID: 25101239
Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma.
Journal of materials chemistry. B, Materials for biology and medicine Dec, 2014 | Pubmed ID: 25485114
Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells.
Biomaterials Feb, 2015 | Pubmed ID: 25542792
Preservation of the greater occipital nerve during suboccipital craniectomy results in a paradoxical increase in postoperative headaches.
Neurosurgery Apr, 2015 | Pubmed ID: 25599212
Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain.
Advanced healthcare materials May, 2015 | Pubmed ID: 25761435
The TWEAK receptor Fn14 is a potential cell surface portal for targeted delivery of glioblastoma therapeutics.
Oncogene 04, 2016 | Pubmed ID: 26300004
Surface plasmon resonance as a high throughput method to evaluate specific and non-specific binding of nanotherapeutics.
Journal of controlled release : official journal of the Controlled Release Society Dec, 2015 | Pubmed ID: 26415854
Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier.
Current pharmaceutical design , 2016 | Pubmed ID: 26685681
Pathologic deposition of non-amyloid immunoglobulin in the brain leading to mass effect and neurological deficits.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia Aug, 2016 | Pubmed ID: 26954763
Pulsed ultrasound expands the extracellular and perivascular spaces of the brain.
Brain research Sep, 2016 | Pubmed ID: 27369449
Non-specific binding and steric hindrance thresholds for penetration of particulate drug carriers within tumor tissue.
Journal of controlled release : official journal of the Controlled Release Society Sep, 2016 | Pubmed ID: 27460683
Emerging Applications of Therapeutic Ultrasound in Neuro-oncology: Moving Beyond Tumor Ablation.
Neurosurgery Nov, 2016 | Pubmed ID: 27552589
Repurposing platinum-based chemotherapies for multi-modal treatment of glioblastoma.
Oncoimmunology , 2016 | Pubmed ID: 27757301
Tumor-targeted nanotherapeutics: overcoming treatment barriers for glioblastoma.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology Nov, 2016 | Pubmed ID: 27813323
Genetically engineered rat gliomas: PDGF-driven tumor initiation and progression in tv-a transgenic rats recreate key features of human brain cancer.
PloS one , 2017 | Pubmed ID: 28358926
Decreased non-specific adhesivity, receptor targeted (DART) nanoparticles exhibit improved dispersion, cellular uptake, and tumor retention in invasive gliomas.
Journal of controlled release : official journal of the Controlled Release Society Dec, 2017 | Pubmed ID: 28887134
Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma.
Scientific reports 01, 2018 | Pubmed ID: 29352201
MR-guided transcranial focused ultrasound safely enhances interstitial dispersion of large polymeric nanoparticles in the living brain.
PloS one , 2018 | Pubmed ID: 29415084
Differential expression of the TWEAK receptor Fn14 in IDH1 wild-type and mutant gliomas.
Journal of neuro-oncology Jun, 2018 | Pubmed ID: 29453678
The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance.
Neuro-oncology 09, 2018 | Pubmed ID: 29897522
Oxaliplatin disrupts pathological features of glioma cells and associated macrophages independent of apoptosis induction.
Journal of neuro-oncology Dec, 2018 | Pubmed ID: 30132163
Prognostic models for patients with brain metastases after stereotactic radiosurgery with or without whole brain radiotherapy: a validation study.
Journal of neuro-oncology Nov, 2018 | Pubmed ID: 30132164
Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma.
Frontiers in oncology , 2018 | Pubmed ID: 30406029
Leveraging Surface Plasmon Resonance to Dissect the Interfacial Properties of Nanoparticles: Implications for Tissue Binding and Tumor Penetration.
Nanomedicine : nanotechnology, biology, and medicine 08, 2019 | Pubmed ID: 31176045
Radiosensitization of high-grade gliomas through induced hyperthermia: Review of clinical experience and the potential role of MR-guided focused ultrasound.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 01, 2020 | Pubmed ID: 31431370
Systematic Evaluation of Light-Activatable Biohybrids for Anti-Glioma Photodynamic Therapy.
Journal of clinical medicine Aug, 2019 | Pubmed ID: 31438568
Predictors and Limitations of the Penetration Depth of Photodynamic Effects in the Rodent Brain.
Photochemistry and photobiology 03, 2020 | Pubmed ID: 31441057
Decreased nonspecific adhesivity, receptor-targeted therapeutic nanoparticles for primary and metastatic breast cancer.
Science advances 01, 2020 | Pubmed ID: 31998833
MCT4 regulates de novo pyrimidine biosynthesis in GBM in a lactate-independent manner.
Neuro-oncology advances Jan-Dec, 2020 | Pubmed ID: 32002519
A multi-center analysis of single-fraction versus hypofractionated stereotactic radiosurgery for the treatment of brain metastasis.
Radiation oncology (London, England) May, 2020 | Pubmed ID: 32466775
Bone Flap Resorption in Pediatric Patients Following Autologous Cranioplasty.
Operative neurosurgery (Hagerstown, Md.) 04, 2021 | Pubmed ID: 33469664
Leveraging the replication-competent avian-like sarcoma virus/tumor virus receptor-A system for modeling human gliomas.
Glia 09, 2021 | Pubmed ID: 33638562
Elevated fibroblast growth factor-inducible 14 expression transforms proneural-like gliomas into more aggressive and lethal brain cancer.
Glia 09, 2021 | Pubmed ID: 33991013
Localized blood-brain barrier opening in infiltrating gliomas with MRI-guided acoustic emissions-controlled focused ultrasound.
Proceedings of the National Academy of Sciences of the United States of America 09, 2021 | Pubmed ID: 34504017
Harnessing nanomedicine for enhanced immunotherapy for breast cancer brain metastases.
Drug delivery and translational research 12, 2021 | Pubmed ID: 34716900
Towards controlled drug delivery in brain tumors with microbubble-enhanced focused ultrasound.
Advanced drug delivery reviews 01, 2022 | Pubmed ID: 34801617
Pediatric glioblastoma: mechanisms of immune evasion and potential therapeutic opportunities.
Cancer immunology, immunotherapy : CII Jan, 2022 | Pubmed ID: 35020009
The roles of thermal and mechanical stress in focused ultrasound-mediated immunomodulation and immunotherapy for central nervous system tumors.
Journal of neuro-oncology Apr, 2022 | Pubmed ID: 35235137
Safwan Alomari1,
Jayanidhi Kedda1,
Adarsha P. Malla2,3,
Victor Pacis1,
Pavlos Anastasiadis2,3,
Su Xu4,
Emylee McFarland2,3,
Lilia Sukhon1,
Bruno Gallo5,
Jordina Rincon-Torroella1,
Netanel Ben-Shalom1,
Heather M. Ames3,6,
Henry Brem1,7,
Graeme F. Woodworth2,3,
Betty Tyler1
1Department of Neurosurgery, Johns Hopkins University School of Medicine,
2Department of Neurosurgery, University of Maryland School of Medicine,
3Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine,
4Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine,
5, Pontifical Catholic University of Parana,
6Department of Pathology, University of Maryland School of Medicine,
7Departments of Ophthalmology, Oncology and Biomedical Engineering, Johns Hopkins University School of Medicine