Department of Translational Molecular Pathology
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Validation of multiplex immunofluorescence panels using multispectral microscopy for immune-profiling of formalin-fixed and paraffin-embedded human tumor tissues.
Scientific reports Oct, 2017 | Pubmed ID: 29042640
Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches.
Journal for immunotherapy of cancer Jun, 2018 | Pubmed ID: 29871672
A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms.
Cancer informatics , 2018 | Pubmed ID: 30013304
Acute myeloid leukemia with a novel CPSF6-RARG variant is sensitive to homoharringtonine and cytarabine chemotherapy.
American journal of hematology Feb, 2020 | Pubmed ID: 31769058
Procedural Requirements and Recommendations for Multiplex Immunofluorescence Tyramide Signal Amplification Assays to Support Translational Oncology Studies.
Cancers Jan, 2020 | Pubmed ID: 31972974
Variants in Epithelial-Mesenchymal Transition and Immune Checkpoint Genes Are Associated With Immune Cell Profiles and Predict Survival in Non-Small Cell Lung Cancer.
Archives of pathology & laboratory medicine 10, 2020 | Pubmed ID: 32150457
A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel, and Nintedanib for Resectable Non-Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Jul, 2020 | Pubmed ID: 32193228
TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Apr, 2021 | Pubmed ID: 33011748
Identification of distinct immune landscapes using an automated nine-color multiplex immunofluorescence staining panel and image analysis in paraffin tumor tissues.
Scientific reports 02, 2021 | Pubmed ID: 33633208
Immuno-profiling and cellular spatial analysis using five immune oncology multiplex immunofluorescence panels for paraffin tumor tissue.
Scientific reports 04, 2021 | Pubmed ID: 33875760
Multi-institutional TSA-amplified Multiplexed Immunofluorescence Reproducibility Evaluation (MITRE) Study.
Journal for immunotherapy of cancer Jul, 2021 | Pubmed ID: 34266881
Effector memory cytotoxic CD3/CD8/CD45RO T cells are predictive of good survival and a lower risk of recurrence in triple-negative breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Nov, 2021 | Pubmed ID: 34839351
Accounting for EGFR Mutations in Epidemiologic Analyses of Non-Small Cell Lung Cancers: Examples Based on the International Lung Cancer Consortium Data.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Mar, 2022 | Pubmed ID: 35027437
Analysis of Immune Intratumor Heterogeneity Highlights Immunoregulatory and Coinhibitory Lymphocytes as Hallmarks of Recurrence in Stage I Non-Small Cell Lung Cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Jan, 2023 | Pubmed ID: 36788067
Abnormally localized DLK1 interacts with NCOR1 in non-small cell lung cancer cell nuclear.
Bioscience reports Dec, 2019 | Pubmed ID: 31661545
p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer.
Signal transduction and targeted therapy May, 2020 | Pubmed ID: 32457342
3-Methyladenine Alleviates Experimental Subretinal Fibrosis by Inhibiting Macrophages and M2 Polarization Through the PI3K/Akt Pathway.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Oct, 2020 | Pubmed ID: 32552228
Systematic Investigation of mRNA -Methyladenosine Machinery in Primary Prostate Cancer.
Disease markers , 2020 | Pubmed ID: 33273988
SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 33681224
Improvement of human embryonic stem cell-derived retinal pigment epithelium cell adhesion, maturation, and function through coating with truncated recombinant human vitronectin.
International journal of ophthalmology , 2021 | Pubmed ID: 34414078
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Cell death & disease Oct, 2021 | Pubmed ID: 34628463
Determining the optimal stage for cryopreservation of human embryonic stem cell-derived retinal pigment epithelial cells.
Stem cell research & therapy Sep, 2022 | Pubmed ID: 36064625
Bifidobacterium promotes retinal ganglion cell survival by regulating the balance of retinal glial cells.
CNS neuroscience & therapeutics Jun, 2023 | Pubmed ID: 36924268
METTL3-mediated m6A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial-mesenchymal transition.
Journal of molecular cell biology Aug, 2023 | Pubmed ID: 36945110
The University of Texas MD Anderson Cancer Center
Shanghai Jiao Tong University School of Medicine
National Clinical Research Center for Eye Diseases
Shanghai Clinical Research Center for Eye Diseases
Shanghai Key Clinical Specialty
Shanghai Key Laboratory of Ocular Fundus Diseases
Shanghai Engineering Center for Visual Science and Photomedicine
Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases
Xinyue Bai*,1,2,3,4,5,6,7,
Ting Zhang*,1,2,3,4,5,6,7,
Xinyue Zhu1,2,3,4,5,6,7,
Xianyu Huang1,2,3,4,5,6,7,
Haiyun Liu1,2,3,4,5,6,7,
Xiaoyan Ding8,
Mei Jiang1,2,3,4,5,6,7,
Xiaodong Sun1,2,3,4,5,6,7
1Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine,
2, National Clinical Research Center for Eye Diseases,
3, Shanghai Clinical Research Center for Eye Diseases,
4, Shanghai Key Clinical Specialty,
5, Shanghai Key Laboratory of Ocular Fundus Diseases,
6, Shanghai Engineering Center for Visual Science and Photomedicine,
7, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases,
8Stem Cell Core Facility, CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences