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Wilmot Cancer Institute,
Department of Biomedical Genetics,
Genomics Research Center
John M. Ashton has not added Biography.
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Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.
Cell stem cell Sep, 2012 | Pubmed ID: 22863534
BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.
Cell stem cell Mar, 2013 | Pubmed ID: 23333149
Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia.
PloS one , 2015 | Pubmed ID: 26177509
Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.
Cell stem cell Jul, 2016 | Pubmed ID: 27374788
Evolution of acute myelogenous leukemia stem cell properties following treatment and progression.
Blood Jul, 2016 | Pubmed ID: 27421961
Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1.
Haematologica Jun, 2017 | Pubmed ID: 28280079
Developmental alcohol exposure impairs synaptic plasticity without overtly altering microglial function in mouse visual cortex.
Brain, behavior, and immunity Jan, 2018 | Pubmed ID: 28918081
Index case of acute myeloid leukemia in a family harboring a novel germ line mutation.
Blood advances Mar, 2017 | Pubmed ID: 29296967
T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy.
JCI insight Feb, 2018 | Pubmed ID: 29467329
Targeting the gut microbiome to treat the osteoarthritis of obesity.
JCI insight Apr, 2018 | Pubmed ID: 29669931
ARID1A, a SWI/SNF subunit, is critical to acinar cell homeostasis and regeneration and is a barrier to transformation and epithelial-mesenchymal transition in the pancreas.
Gut Jul, 2019 | Pubmed ID: 30228219
Decellularized Wharton jelly matrix: a biomimetic scaffold for ex vivo hematopoietic stem cell culture.
Blood advances Apr, 2019 | Pubmed ID: 30940636
A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups.
Journal of biomolecular techniques : JBT Apr, 2020 | Pubmed ID: 31969795
Scaffold-mediated CRISPR-Cas9 delivery system for acute myeloid leukemia therapy.
Science advances May, 2021 | Pubmed ID: 34138728
Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse.
Scientific reports Feb, 2022 | Pubmed ID: 35194136
Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors .
Journal of medicinal chemistry Apr, 2022 | Pubmed ID: 35404047
Comparative Analysis of Single-Cell RNA Sequencing Platforms and Methods.
Journal of biomolecular techniques : JBT Dec, 2021 | Pubmed ID: 35837267
University of Rochester Medical Center
Christina M. Kaszuba1,2,
Benjamin J. Rodems1,3,
Sonali Sharma1,3,
Edgardo I. Franco1,2,
John M. Ashton1,3,4,
Laura M. Calvi1,5,
Jeevisha Bajaj1,3
1Wilmot Cancer Institute, University of Rochester Medical Center,
2Department of Biomedical Engineering, University of Rochester,
3Department of Biomedical Genetics, University of Rochester Medical Center,
4Genomics Research Center, University of Rochester Medical Center,
5Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center
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