Babu L. Tekwani

A physiochemical mechanism of hemozoin (beta-hematin) synthesis by malaria parasite.

Peripheral blood leucocytes ornithine decarboxylase activity in chronic myeloid leukemia patients: prognostic and therapeutic implications.

Haem polymerase as a novel target of antimalarial action of cyproheptadine.

Synthesis and biological evaluation of new imidazo[1,2-a]pyridine derivatives designed as mefloquine analogues.

A novel active DNA topoisomerase I in Leishmania donovani.

Antimicrobial and antiparasitic (+)-trans-hexahydrodibenzopyrans and analogues from Machaerium multiflorum.

New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge.

Flow cytometric analysis of aneuploidy and S-phase fraction in chronic myeloid leukemia patients: role in early detection of accelerated phase.

Antiparasitic alkaloids from Psychotria klugii.

Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.

Molecular and functional characterization of adenylate kinase 2 gene from Leishmania donovani.

Spectrophotometric determination of de novo hemozoin/beta-hematin formation in an in vitro assay.

Antimalarial and antileishmanial activities of aroyl-pyrrolyl-hydroxyamides, a new class of histone deacetylase inhibitors.

A new antimalarial quassinoid from Simaba orinocensis.

Piperazine-linked bisbenzamidines: a novel class of antileishmanial agents.

An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme.

Three new manzamine alkaloids from a common Indonesian sponge and their activity against infectious and tropical parasitic diseases.

Antimicrobial and antileishmanial activities of hypocrellins A and B.

Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay.

Bisnortriterpenes from Salacia madagascariensis.

Synthesis, antimalarial, antileishmanial, and antimicrobial activities of some 8-quinolinamine analogues.

Polyamine transport in parasites: a potential target for new antiparasitic drug development.

Biomimetic synthesis, antimicrobial, antileishmanial and antimalarial activities of euglobals and their analogues.

Aromatic constituents of Uvaria grandiflora.

Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases.

Anti-plasmodial and anti-leishmanial activity of conformationally restricted pentamidine congeners.

Antiprotozoal and antimicrobial activities of O-alkylated and formylated acylphloroglucinols.

8-Aminoquinolines: future role as antiprotozoal drugs.

Synthesis, antimalarial, antileishmanial, antimicrobial, cytotoxicity, and methemoglobin (MetHB) formation activities of new 8-quinolinamines.

A new library of C-16 modified artemisinin analogs and evaluation of their anti-parasitic activities.

Synthesis of isoquinuclidine analogs of chloroquine: antimalarial and antileishmanial activity.

Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors.

Antileishmanial, antiplasmodial and cytotoxic activities of 12,16-dideoxy aegyptinone B from Zhumeria majdae Rech.f. & Wendelbo.

S-Euglobals: biomimetic synthesis, antileishmanial, antimalarial, and antimicrobial activities.

Growth, drug susceptibility, and gene expression profiling of Plasmodium falciparum cultured in medium supplemented with human serum or lipid-rich bovine serum albumin [corrected].

Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy.

Novel bisbenzimidazoles with antileishmanial effectiveness.

Probing the structures of leishmanial farnesyl pyrophosphate synthases: homology modeling and docking studies.

Structural analysis of farnesyl pyrophosphate synthase from parasitic protozoa, a potential chemotherapeutic target.

Infectious disorders drug targets--an arsenal of knowledge on pathogen targets.

Antileishmanial activity screening of 5-nitro-2-heterocyclic benzylidene hydrazides.

Kinetic studies and bioactivity of potential manzamine prodrugs.

Current antiparasitic drug targets and a paradigm shift in discovery of new antiparasitic drugs and vaccines.

Plasmodium falciparum serine/threonine phoshoprotein phosphatases (PPP): from housekeeper to the 'holy grail'.

Antiparasitic, nematicidal and antifouling constituents from Juniperus berries.

Indolizidine, antiinfective and antiparasitic compounds from Prosopis glandulosa var. glandulosa.

Synthesis and antimalarial activities of cyclen 4-aminoquinoline analogs.

Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants.

Bioactive (+)-manzamine A and (+)-8-hydroxymanzamine A tertiary bases and salts from Acanthostrongylophora ingens and their preparations.

Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.

Antimicrobial, antiparasitic and cytotoxic spermine alkaloids from Albizia schimperiana.

Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket.

Structure-activity relationship studies of manzamine A: amidation of positions 6 and 8 of the beta-carboline moiety.

Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers.

Banisteriopsis caapi, a unique combination of MAO inhibitory and antioxidative constituents for the activities relevant to neurodegenerative disorders and Parkinson's disease.

Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.

Biologically active tetranorditerpenoids from the fungus Sclerotinia homoeocarpa causal agent of dollar spot in turfgrass.

Cytochrome P450-dependent toxicity of dapsone in human erythrocytes.

Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections.

Composition, standardization and chemical profiling of Banisteriopsis caapi, a plant for the treatment of neurodegenerative disorders relevant to Parkinson's disease.

Anti-infective discorhabdins from a deep-water alaskan sponge of the genus Latrunculia.

A structure-activity relationship study of the antimalarial and antileishmanial activities of nonpeptide macrocyclic histone deacetylase inhibitors.

Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum.

Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton.

The antiplasmodial activity of norcantharidin analogs.

Analysis of primaquine and its metabolite carboxyprimaquine in biological samples: enantiomeric separation, method validation and quantification.

Synthesis, antiprotozoal, antimicrobial, β-hematin inhibition, cytotoxicity and methemoglobin (MetHb) formation activities of bis(8-aminoquinolines).

Antiparasitic and antimicrobial indolizidines from the leaves of Prosopis glandulosa var. glandulosa.

Identification of novel malarial cysteine protease inhibitors using structure-based virtual screening of a focused cysteine protease inhibitor library.

An entry to curcuphenol/elvirol core structures via a retro-Aldol reaction.

Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi.

Synthesis and antikinetoplastid activity of a series of N,N'-substituted diamines.

Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.

Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway.

Amino acid, dipeptide and pseudodipeptide conjugates of ring-substituted 8-aminoquinolines: synthesis and evaluation of anti-infective, β-haematin inhibition and cytotoxic activities.

Antiprotozoal and antimicrobial compounds from the plant pathogen Septoria pistaciarum.

Synthesis and biological evaluation of tricyclic guanidine analogues of batzelladine K for antimalarial, antileishmanial, antibacterial, antifungal and anti-HIV activities.

Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B.

Pentacyclic ingamine alkaloids, a new antiplasmodial pharmacophore from the marine sponge Petrosid Ng5 Sp5.

Synthesis and Structure-Activity Relationships of Lansine Analogues as Antileishmanial Agents.

Antimicrobial and antiprotozoal activities of secondary metabolites from the fungus Eurotium repens.

Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus.