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S'identifier
Laboratory of Molecular and Physiopathological Bases of Osteochondrodysplasia,
Imagine Institute,
Laboratory of Molecular and Physiopathological Bases of Osteochondrodysplasia, Imagine Institute
Laurence Legeai-Mallet has not added Biography.
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Key challenges in the treatment of rare pediatric skeletal genetic disorders: from bench to bedside.
Drug discovery today Jul, 2015 | Pubmed ID: 25943098
Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible.
Human molecular genetics Jul, 2016 | Pubmed ID: 27260401
Animal models of craniosynostosis.
Neuro-Chirurgie Nov, 2019 | Pubmed ID: 31563616
Novel therapeutic approaches for the treatment of achondroplasia.
Bone Dec, 2020 | Pubmed ID: 32795681
Tyrosine kinases regulate chondrocyte hypertrophy: promising drug targets for Osteoarthritis.
Osteoarthritis and cartilage Oct, 2021 | Pubmed ID: 34284112
Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia.
Bone research Jan, 2022 | Pubmed ID: 35078974
Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralization in mice.
JCI insight Jun, 2023 | Pubmed ID: 37345656
Embryonic cranial cartilage defects in the Fgfr3 mouse model of achondroplasia.
Anatomical record (Hoboken, N.J. : 2007) Sep, 2023 | Pubmed ID: 37747411
Low-dose infigratinib increases bone growth and corrects growth plate abnormalities in an achondroplasia mouse model.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jul, 2024 | Pubmed ID: 38590263
Université de Paris Cité
Anne Morice1,
Emilie Panafieu2,
Amélie De la Seiglière1,
Laurence Legeai-Mallet1
1Laboratory of Molecular and Physiopathological Bases of Osteochondrodysplasia, Imagine Institute, Université de Paris Cité,
2SFR Necker INSERM, LEAT antenne Imagine
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