Laurence Legeai-Mallet

Key challenges in the treatment of rare pediatric skeletal genetic disorders: from bench to bedside.

Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible.

Animal models of craniosynostosis.

Novel therapeutic approaches for the treatment of achondroplasia.

Tyrosine kinases regulate chondrocyte hypertrophy: promising drug targets for Osteoarthritis.

Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia.

Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralization in mice.

Embryonic cranial cartilage defects in the Fgfr3 mouse model of achondroplasia.

Low-dose infigratinib increases bone growth and corrects growth plate abnormalities in an achondroplasia mouse model.