School of Biomedical Engineering and Department of Medical Genetics
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Latest developments and in vivo use of the Tet system: ex vivo and in vivo delivery of tetracycline-regulated genes.
Current opinion in biotechnology Oct, 2002 | Pubmed ID: 12459336
Contribution of hematopoietic stem cells to skeletal muscle.
Nature medicine Dec, 2003 | Pubmed ID: 14625543
Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1.
Nature immunology Jun, 2005 | Pubmed ID: 15880112
Strategies of conditional gene expression in myocardium: an overview.
Methods in molecular medicine , 2005 | Pubmed ID: 16010014
Methods for examining stem cells in post-ischemic and transplanted hearts.
Methods in molecular medicine , 2005 | Pubmed ID: 16010020
Circulating myogenic progenitors and muscle repair.
Seminars in cell & developmental biology Aug-Oct, 2005 | Pubmed ID: 16087371
Bone marrow-derived recipient cells in murine transplanted hearts: potential roles and the effect of immunosuppression.
Laboratory investigation; a journal of technical methods and pathology Aug, 2005 | Pubmed ID: 16205656
Ex vivo expansion of rat bone marrow mesenchymal stromal cells on microcarrier beads in spin culture.
Biomaterials Jul, 2007 | Pubmed ID: 17433434
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.
Nature neuroscience Dec, 2007 | Pubmed ID: 18026097
Effects of granulocyte-colony stimulating factor on bone marrow-derived progenitor cells in murine cardiac transplantation.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology Jan-Feb, 2010 | Pubmed ID: 19144547
Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25.
The Journal of experimental medicine Apr, 2009 | Pubmed ID: 19289576
Silencing inhibits Cre-mediated recombination of the Z/AP and Z/EG reporters in adult cells.
PloS one , 2009 | Pubmed ID: 19415111
Depot-specific differences in adipogenic progenitor abundance and proliferative response to high-fat diet.
Stem cells (Dayton, Ohio) Oct, 2009 | Pubmed ID: 19658193
Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis.
Nature cell biology Feb, 2010 | Pubmed ID: 20081841
Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function.
The Journal of experimental medicine May, 2010 | Pubmed ID: 20421388
Periodontal regeneration using engineered bone marrow mesenchymal stromal cells.
Biomaterials Nov, 2010 | Pubmed ID: 20832109
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool.
Nature neuroscience Sep, 2011 | Pubmed ID: 21804537
p53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice.
Molecular cell Aug, 2011 | Pubmed ID: 21855805
CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration.
Stem cells (Dayton, Ohio) Dec, 2011 | Pubmed ID: 21997891
Targeted cell fusion facilitates stable heterokaryon generation in vitro and in vivo.
PloS one , 2011 | Pubmed ID: 22039476
Functionally convergent white adipogenic progenitors of different lineages participate in a diffused system supporting tissue regeneration.
Stem cells (Dayton, Ohio) Jun, 2012 | Pubmed ID: 22415977
Role of stem/progenitor cells in reparative disorders.
Fibrogenesis & tissue repair , 2012 | Pubmed ID: 23270300
Control of the hippo pathway by Set7-dependent methylation of Yap.
Developmental cell Jul, 2013 | Pubmed ID: 23850191
Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation.
The Journal of clinical investigation May, 2014 | Pubmed ID: 24667637
In vivo characterization of neural crest-derived fibro/adipogenic progenitor cells as a likely cellular substrate for craniofacial fibrofatty infiltrating disorders.
Biochemical and biophysical research communications Aug, 2014 | Pubmed ID: 25073114
The role of microglia in human disease: therapeutic tool or target?
Acta neuropathologica Sep, 2014 | Pubmed ID: 25107477
(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2014 | Pubmed ID: 25136132
Submyeloablative conditioning with busulfan permits bone marrow-derived cell accumulation in a murine model of Alzheimer's disease.
Neuroscience letters Jan, 2015 | Pubmed ID: 25582787
Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors.
Nature medicine Jul, 2015 | Pubmed ID: 26053624
Skeletal muscle-resident MSCs and bone formation.
Bone Nov, 2015 | Pubmed ID: 26103092
SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling.
Developmental cell Apr, 2016 | Pubmed ID: 27046831
Origin, fate and dynamics of macrophages at central nervous system interfaces.
Nature immunology Jul, 2016 | Pubmed ID: 27135602
The lysine methyltransferase Ehmt2/G9a is dispensable for skeletal muscle development and regeneration.
Skeletal muscle , 2016 | Pubmed ID: 27239264
Pharmacological blockage of fibro/adipogenic progenitor expansion and suppression of regenerative fibrogenesis is associated with impaired skeletal muscle regeneration.
Stem cell research Jul, 2016 | Pubmed ID: 27376715
Fibro/Adipogenic Progenitors (FAPs): Isolation by FACS and Culture.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28247350
Increased plasma lipid levels exacerbate muscle pathology in the mdx mouse model of Duchenne muscular dystrophy.
Skeletal muscle Sep, 2017 | Pubmed ID: 28899419
Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential.
Cell stem cell Feb, 2018 | Pubmed ID: 29395054
Microglia's heretical self-renewal.
Nature neuroscience Apr, 2018 | Pubmed ID: 29593318
The origins and non-canonical functions of macrophages in development and regeneration.
Development (Cambridge, England) May, 2019 | Pubmed ID: 31048317
Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration.
Cell stem cell Dec, 2019 | Pubmed ID: 31809738
Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors.
Cell stem cell Feb, 2020 | Pubmed ID: 31978365
Closing gaps, opening doors: an experimental collaboration in stem cell intervention.
Molecular biology reports May, 2020 | Pubmed ID: 32372173
Towards stem cell therapies for skeletal muscle repair.
NPJ Regenerative medicine , 2020 | Pubmed ID: 32411395
TGF-β-driven downregulation of the transcription factor TCF7L2 affects Wnt/β-catenin signaling in PDGFRα fibroblasts.
Journal of cell science Jun, 2020 | Pubmed ID: 32434871
Cardiac fibroblast diversity in health and disease.
Matrix biology : journal of the International Society for Matrix Biology Sep, 2020 | Pubmed ID: 32446910
Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing.
Cell stem cell Sep, 2020 | Pubmed ID: 32755548
Systemic hypoxia mimicry enhances axonal regeneration and functional recovery following peripheral nerve injury.
Experimental neurology Dec, 2020 | Pubmed ID: 32814068
Evolving Roles of Muscle-Resident Fibro-Adipogenic Progenitors in Health, Regeneration, Neuromuscular Disorders, and Aging.
Frontiers in physiology , 2021 | Pubmed ID: 33959042
Fibroblast and Myofibroblast Subtypes: Single Cell Sequencing.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 34028734
Adipocyte death triggers a pro-inflammatory response and induces metabolic activation of resident macrophages.
Cell death & disease Jun, 2021 | Pubmed ID: 34091595
Origins, potency, and heterogeneity of skeletal muscle fibro-adipogenic progenitors-time for new definitions.
Skeletal muscle Jul, 2021 | Pubmed ID: 34210364
Macrophages in Skeletal Muscle Dystrophies, An Entangled Partner.
Journal of neuromuscular diseases , 2022 | Pubmed ID: 34542080
Multipotent stromal cells: One name, multiple identities.
Cell stem cell Oct, 2021 | Pubmed ID: 34624231
Human skeletal muscle CD90 fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients.
Cell metabolism Nov, 2021 | Pubmed ID: 34678202
Emerging skeletal muscle stromal cell diversity: Functional divergence in fibro/adipogenic progenitor and mural cell populations.
Experimental cell research Jan, 2022 | Pubmed ID: 34822813
Pleiotropic activation of endothelial function by angiotensin II receptor blockers is crucial to their protective anti-vascular remodeling effects.
Scientific reports 06, 2022 | Pubmed ID: 35697767
Methylation of the Hippo effector YAP by the methyltransferase SETD7 drives myocardial ischaemic injury: a translational study.
Cardiovascular research Jan, 2023 | Pubmed ID: 35709329
Metabolic reprogramming of skeletal muscle by resident macrophages points to CSF1R inhibitors as muscular dystrophy therapeutics.
Science translational medicine Jun, 2022 | Pubmed ID: 35767650
Thermoneutral Housing and a Western Diet Combination Exacerbates Dysferlin-Deficient Muscular Dystrophy.
Muscle & nerve Oct, 2022 | Pubmed ID: 35859452
TNFα and IFNγ cooperate for efficient pro- to anti-inflammatory transition of macrophages during muscle regeneration.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2022 | Pubmed ID: 36279473
Spatial compartmentalization of signaling imparts source-specific functions on secreted factors.
Cell reports Feb, 2023 | Pubmed ID: 36729831
Activation of β-catenin in mesenchymal progenitors leads to muscle mass loss.
Developmental cell Mar, 2023 | Pubmed ID: 36898377
Protocol for generation of a time-resolved cellular interactome during tissue remodeling in adult mice.
STAR protocols Dec, 2023 | Pubmed ID: 37831606
DPPIV fibro-adipogenic progenitors form the niche of adult skeletal muscle self-renewing resident macrophages.
Nature communications Dec, 2023 | Pubmed ID: 38092736
Spatiotemporal signaling underlies progressive vascular rarefaction in myocardial infarction.
Nature communications Dec, 2023 | Pubmed ID: 38129410
Cellular activation patterns of CD10+ fibro-adipogenic progenitors across acquired disease states in human skeletal muscle biopsies.
Free neuropathology Jan, 2024 | Pubmed ID: 38357523
Origins and functions of eosinophils in two non-mucosal tissues.
Frontiers in immunology , 2024 | Pubmed ID: 38585275
Fibroblast and myofibroblast activation in normal tissue repair and fibrosis.
Nature reviews. Molecular cell biology Aug, 2024 | Pubmed ID: 38589640
Rebuilding and rebooting immunity with stem cells.
Cell stem cell May, 2024 | Pubmed ID: 38593798
Author Correction: Fibroblast and myofibroblast activation in normal tissue repair and fibrosis.
Nature reviews. Molecular cell biology Aug, 2024 | Pubmed ID: 38740927
Sex-biased human thymic architecture guides T cell development through spatially defined niches.
Developmental cell Oct, 2024 | Pubmed ID: 39383865